XXY JOURNEY PROBLEMATIKA INDIVIDU INTERSEKS DALAM DRAWING DENGAN METODE AUTOETNOGRAFI

Chromosome Mosaicism ◽

Sex Development ◽

Bahasa Indonesia

Keberadaan individu interseks berikut segala isu yang terkait dengan eksistensi mereka bukanlah hal yang baru dalam masyarakat, eksistensi interseks adalah sebuah kasus nyata dan bukan hanya dongeng tentang hermaprodit yang berasal dari mitologi Yunani. Pada abad 8 M, catatan keputusan hukum Islam membahas individu-individu yang dikenal dalam bahasa Arab sebagai khuntha dan PBB menyatakan sekitar 1,7% penduduk dunia adalah interseks. Dalam istilah Bahasa Indonesia, seringkali digunakan istilah kerancuan kelamin atau kelamin ganda. Interseks atau saat ini disebut DSD (Disorders of Sex Development). Latar belakang penulis yang terlahir interseks dengan kromosom 47XXY chromosome mosaicism penulis terdorong untuk berbagi pengalaman, mengalami sebagai individu interseks memaparkan kompleksitas dan problematika individu interseks dari masa anak-anak hingga dewasa, dengan pendekatan yaitu metode autoetnografi dalam penciptaan karya drawing dengan visual self portrait, penerapan metode Autoethografi juga dilakukan untuk memahami diri sendiri (self-narative) melalui penciptaan karya drawingKata kunci: Interseks, Autoetnografi, drawing.

Psychosexual Aspects, Effects of Prenatal Androgen Exposure, and Gender Change in 46,XY Disorders of Sex Development

Yearbook of Paediatric Endocrinology ◽

10.1530/ey.16.6.8 ◽

2019 ◽

Author(s):

Loch Batista R ◽

Inacio M ◽

Prado Arnhold IJ ◽

Gomes NL ◽

Diniz Faria JA ◽

...

Keyword(s):

Sex Development ◽

Androgen Exposure ◽

Prenatal Androgen Exposure ◽

And Gender ◽

Prenatal Androgen ◽

Gender Change

Faculty Opinions recommendation of Disorders of sex development: diagnostic approaches and management options-an islamic perspective.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13414970.14789070 ◽

2011 ◽

Author(s):

Pierre Mouriquand

Keyword(s):

Management Options ◽

Islamic Perspective ◽

Sex Development ◽

Diagnostic Approaches

Faculty Opinions recommendation of Genital surgery for disorders of sex development: implementing a shared decision-making approach.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5019957.4952055 ◽

2010 ◽

Author(s):

David E Sandberg

Keyword(s):

Decision Making ◽

Shared Decision Making ◽

Shared Decision ◽

Genital Surgery ◽

Chromosome Abnormalities in Domestic Animals as Causes of Disorders of Sex Development or Impaired Fertility

Insights from Animal Reproduction ◽

10.5772/62053 ◽

2016 ◽

Cited By ~ 2

Author(s):

Izabela Szczerbal ◽

Marek Switonski

Keyword(s):

Domestic Animals ◽

Chromosome Abnormalities ◽

Molecular study and genotype–phenotype in Chinese female patients with 46, XY disorders of sex development

Gynecological Endocrinology ◽

10.1080/09513590.2021.1960307 ◽

2021 ◽

pp. 1-7

Author(s):

Junke Xia ◽

Jing Wu ◽

Chen Chen ◽

Zhenhua Zhao ◽

Yanchuan Xie ◽

...

Keyword(s):

Molecular Study ◽

Female Patients ◽

Comprehensive transcriptome analysis of hypothalamus reveals genes associated with disorders of sex development in pigs

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/j.jsbmb.2021.105875 ◽

2021 ◽

pp. 105875

Author(s):

Shuwen Tan ◽

Yi Zhou ◽

Haiquan Zhao ◽

Jinhua Wu ◽

Hui Yu ◽

...

Keyword(s):

Transcriptome Analysis ◽

Genome analyses and androgen quantification for an infant with 5α-reductase type 2 deficiency

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2020-0678 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Kazuhisa Akiba ◽

Keiko Aso ◽

Yukihiro Hasegawa ◽

Maki Fukami

Keyword(s):

Reference Value ◽

Ambiguous Genitalia ◽

Chinese Patients ◽

Sex Development ◽

Liquid Chromatography Tandem Mass ◽

Exon 1 ◽

Genome Analyses ◽

Immune Assays

Abstract Objectives 5α-reductase type 2 deficiency due to biallelic SRD5A2 variants is a common form of 46,XY disorders of sex development. Case presentation A Chinese neonate presented with ambiguous genitalia. He carried a homozygous likely_pathogenic SRD5A2 variant (c.650C>A, p.A217E). His apparently nonconsanguineous parents were heterozygotes for the variant. The variant has previously been identified in two Chinese patients. Our patient carried 14.2 Mb loss-of-heterogeneity regions distributed in the genome. The SRD5A2 variant in this family was invariably coupled with two polymorphisms in exon 1 and intron 1. In the patient, blood testosterone (T)/5α-dihydrotestosterone (5αDHT) ratios were elevated before and during mini puberty, and were higher when measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) than measured by conventional immune assays. Conclusions This study provides evidence for the founder effect of an SRD5A2 variant. Furthermore, our data indicate that there is a need to establish a new reference value for T/5αDHT ratios using LC-MS/MS.