Skip hemilaminectomy for the treatment of holospinal epidural abscess: A single-center experience

Background: Holospinal epidural abscesses (HEAs) are rare with potentially devastating consequences. Urgent bony decompression and abscess evacuation with long-term antibiotic therapy are typically the treatment of choice. Methods: We reviewed cases of holospinal HEAs operated on between 2009 and 2018. Variables studied included preoperative laboratories, CT/MR studies plus clinical and radiographic follow-up for between 34 and 60 postoperative months. Results: We utilized skip hemilaminectomies to minimize the risks of segmental instability. Targeted antibiotic therapy was also started immediately and maintained for 6 postoperative weeks. MR/CT studies documented full radiographic and neurological recovery between 6 and 12-months later. Conclusion: HEAs may be treated utilizing multilevel skip hemilaminectomies to help maintain spinal stability while offering adequate abscess decompression/resolution.

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Outcome following decompressive craniectomy in children with severe traumatic brain injury: a 10-year single-center experience with long-term follow up

Yearbook of Neurology and Neurosurgery ◽

10.1016/s0513-5117(08)79125-7 ◽

2008 ◽

Vol 2008 ◽

pp. 295-296

Author(s):

A.B. Valadka

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Decompressive Craniectomy ◽

Severe Traumatic Brain Injury ◽

Single Center ◽

Single Center Experience ◽

Long Term Follow Up

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MANAGEMENT OF ENDOSCOPICALLY RESECTED PT1 COLORECTAL CANCER. SURGERY OR FOLLOW UP? SINGLE CENTER EXPERIENCE, LONG TERM FOLLOW UP AND COST ANALYSIS

10.1055/s-0038-1637557 ◽

2018 ◽

Author(s):

G Antonelli ◽

G Berardi ◽

GL Rampioni Vinciguerra ◽

V Domenico Corleto ◽

E Pilozzi ◽

...

Keyword(s):

Colorectal Cancer ◽

Cost Analysis ◽

Cancer Surgery ◽

Single Center ◽

Colorectal Cancer Surgery ◽

Single Center Experience ◽

Long Term Follow Up

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Long-term follow-up of late chronic phase chronic myeloid leukemia patients treated with imatinib after interferon failure: a single center experience

Leukemia & Lymphoma ◽

10.1080/10428194.2021.1901094 ◽

2021 ◽

pp. 1-6

Author(s):

Sara Pepe ◽

Emilia Scalzulli ◽

Gioia Colafigli ◽

Alessio Di Prima ◽

Marco Mancini ◽

...

Keyword(s):

Chronic Myeloid Leukemia ◽

Myeloid Leukemia ◽

Chronic Phase ◽

Single Center ◽

Single Center Experience ◽

Long Term Follow Up

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Long term follow-up of patients with prolactinomas and outcome of dopamine agonist withdrawal: a single center experience

Pituitary ◽

10.1007/s11102-011-0303-6 ◽

2011 ◽

Vol 15 (1) ◽

pp. 25-29 ◽

Cited By ~ 32

Author(s):

Panagiotis Anagnostis ◽

Fotini Adamidou ◽

Stergios A. Polyzos ◽

Zoe Efstathiadou ◽

Eleni Karathanassi ◽

...

Keyword(s):

Dopamine Agonist ◽

Single Center ◽

Single Center Experience ◽

Long Term Follow Up

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The quality of life in extracorporeal life support survivors: single-center experience of a long-term follow-up

Child s Nervous System ◽

10.1007/s00381-018-3999-z ◽

2018 ◽

Vol 35 (2) ◽

pp. 227-235 ◽

Cited By ~ 2

Author(s):

Valentina Di Leo ◽

Paolo Biban ◽

Federico Mercolini ◽

Francesco Martinolli ◽

Andrea Pettenazzo ◽

...

Keyword(s):

Quality Of Life ◽

Life Support ◽

Extracorporeal Life Support ◽

Single Center ◽

Single Center Experience ◽

Long Term Follow Up

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568 Single Center Experience in Paravalvular Leak Closure: Procedural Success and Long-Term Follow-Up

Canadian Journal of Cardiology ◽

10.1016/j.cjca.2012.07.516 ◽

2012 ◽

Vol 28 (5) ◽

pp. S311

Author(s):

R. Ibrahim ◽

S. Noble ◽

A. Basmadjian ◽

M. Jolicoeur ◽

S. Levesque ◽

...

Keyword(s):

Paravalvular Leak ◽

Single Center ◽

Single Center Experience ◽

Long Term Follow Up ◽

Procedural Success

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P.09.6 LONG TERM FOLLOW-UP OF RECURRENT/RESIDUAL COLORECTAL ADENOMAS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION: A SINGLE CENTER EXPERIENCE

Digestive and Liver Disease ◽

10.1016/s1590-8658(16)30255-9 ◽

2016 ◽

Vol 48 ◽

pp. e173-e174

Author(s):

G. Fiori ◽

C. Genco ◽

D. Ravizza ◽

I. Bravi ◽

G. De Roberto ◽

...

Keyword(s):

Endoscopic Submucosal Dissection ◽

Colorectal Adenomas ◽

Single Center ◽

Submucosal Dissection ◽

Single Center Experience ◽

Long Term Follow Up

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MO291RITUXIMAB IS EFFECTIVE AND SAFE IN ADULTS WITH STEROID-DEPENDENT NEPHROTIC SYNDROME: A LONG-TERM, SINGLE-CENTER EXPERIENCE

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab104.0049 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Gemma Patella ◽

Alessandro Comi ◽

Giuseppe Coppolino ◽

Nicolino Comi ◽

Giorgio Fuiano ◽

...

Keyword(s):

Nephrotic Syndrome ◽

Case Series ◽

Adult Patients ◽

Single Center ◽

Single Center Experience ◽

Steroid Dependent ◽

The Mean ◽

Steroid Dependent Nephrotic Syndrome

Abstract Background and Aims Steroid-dependent nephrotic syndrome (SDNS) may require a prolonged multi-drug therapy with risk of drug toxicity and renal failure. Rituximab (RTX) treatment has been found to be helpful in reducing the steroid dosage and the need for immunosuppressants (ISs), but little data are currently available regarding very long-term outcomes in adults. We herein describe a long-term, single-center experience of RTX use in a large series of adults with SDNS. Method We studied 23 adult patients with SDNS (mean age 54.2±17.1 y; 65% male; BMI 28.5±4.7), mostly consequent to membranous (47.8%) or focal glomerulonephritis (30.2 %) who were eligible to start a RTX regimen. Before entering the RTX protocol, proteinuria and eGFR were 7.06±3.87 g/24h and 65.9±28.2 ml/min/1.73 m2, respectively; albumin and CD19/CD20 ratio were 2.9±0.9 g/L and 0.99±0.01 respectively; the mean number of ISs was 2.39±0.89 and the mean annual rate of relapses was 2.2±0.9. Results Patients were followed over a mean follow-up of 64 months (range: 12-144). After RTX (mean dose: 1202.1±372.4 mg) the rate of relapses was virtually nullified (p<0.001). eGFR remained roughly stable (62.1±19.8 ml/min/1.73 m2, p=NS), while proteinuria, albumin, CD19/CD20 and BMI all significantly improved (p ranging from 0.01 to 0.001). The mean number of additional ISs was also reduced (0.44±0.12; p<0.001) and RTX enabled discontinuation of steroids in 13/23 (56.5%) patients. No major adverse events related to therapy were recorded. Conclusion Findings from this large case-series with a remarkable very long follow-up reinforce the role of RTX as an efficient and safe weapon to improve outcomes in adult patients suffering from SDNS.

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