COMMON VARIABLE IMMUNODEFICIENCY, DEPENDENT COSTIMULATION B CELLS MOLECULES AND AUTOIMMUNE HEMATOLOGICAL DISEASES IN ADULTS.

Mapping Intimacies ◽

10.26226/morressier.57bc1755d462b80290b4d8b2 ◽

2016 ◽

Author(s):

Patricia O Farrill

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Hematological Diseases ◽

Common Variable

Download Full-text

Faculty Opinions recommendation of Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1166205.627133 ◽

2009 ◽

Author(s):

Francisco A Bonilla

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Common Variable

Download Full-text

Failure of B cells in common variable immunodeficiency to transit from proliferation to differentiation is associated with altered B cell surface-molecule display

Journal of Allergy and Clinical Immunology ◽

10.1016/0091-6749(89)90177-2 ◽

1989 ◽

Vol 84 (1) ◽

pp. 44-55 ◽

Author(s):

A SAXON ◽

J GIORGI ◽

E SHERR ◽

J KAGAN

Keyword(s):

B Cells ◽

Cell Surface ◽

B Cell ◽

Common Variable Immunodeficiency ◽

Surface Molecule ◽

Cell Surface Molecule ◽

Common Variable

Download Full-text

Phenotypic Comparison of B cells in Discordant Identical Twins with Common Variable Immunodeficiency and Recurrent Sino-Pulmonary Infection Patients

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2011.12.350 ◽

2012 ◽

Vol 129 (2) ◽

pp. AB157

Author(s):

T.A. Hwangpo ◽

E. Szymanska ◽

C.R. Liu ◽

M.G. Brand ◽

E.E. Brown ◽

...

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Pulmonary Infection ◽

Identical Twins ◽

Common Variable

Download Full-text

Common Variable Immunodeficiency / Cvid

Journal of Clinical Review & Case Reports ◽

10.33140/jcrc/03/02/00001 ◽

2018 ◽

Vol 3 (2) ◽

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Autoimmune Disorders ◽

Common Variable

“Variable” refers to the heterogeneousclinicalmanifestations of thisdisorder, which can include: recurrentinfections, chroniclungdisease, autoimmune disorders, also involve varioussegments of the gastrointestinaltract and a heightenedsusceptibility to lymphoma. Itis a primaryimmunodeficiencythataffects 1 in 50,000 peopleworldwide. Itischaracterized by reducedimmunoglobulinserumlevels and absent or impairedantibody production. The pathogenic of CVID isnotknown; however, therehavebeennumerousassociatedlaboratoryfindingsincludingnumerousmutations in the genesresult in dysfunctional B cells. The mostfrequentmutationsoccur in the TNFRSF13B gene. Genesthathavebeenimplicated in monogenic CVID include ICOS, TNFRSF13B (TACI), TNFRSF13C (BAFF-R), TNFSF12 (TWEAK), CD19, CD81, CR2 (CD21), MS4A1 (CD20), TNFRSF7 (CD27), IL21, IL21R, LRBA, CTLA4, PRKCD, PLCG2, NFKB1, NFKB2, PIK3CD, PIK3R1, VAV1, RAC2, BLK, IKZF1 (IKAROS) and IRF2BP2 [1]. In addition, thereisevidence of complexinheritanceratherthan a monogenic CVID.

Download Full-text

Low percentages of regulatory T cells in common variable immunodeficiency (CVID) patients with autoimmune diseases and its association with increased numbers of CD4+CD45RO+ T and CD21low B cells

Allergologia et Immunopathologia ◽

10.1016/j.aller.2019.01.003 ◽

2019 ◽

Vol 47 (5) ◽

pp. 457-466 ◽

Author(s):

G. López-Herrera ◽

N.H. Segura-Méndez ◽

P. O’Farril-Romanillos ◽

M.E. Nuñez-Nuñez ◽

M.C. Zarate-Hernández ◽

...

Keyword(s):

T Cells ◽

B Cells ◽

Regulatory T Cells ◽

Autoimmune Diseases ◽

Common Variable Immunodeficiency ◽

Common Variable

Download Full-text

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0901984106 ◽

2009 ◽

Vol 106 (32) ◽

pp. 13451-13456 ◽

Author(s):

M. Rakhmanov ◽

B. Keller ◽

S. Gutenberger ◽

C. Foerster ◽

M. Hoenig ◽

...

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Common Variable

Download Full-text

Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency

Clinical Immunology ◽

10.1016/j.clim.2016.09.009 ◽

2017 ◽

Vol 175 ◽

pp. 124-132 ◽

Author(s):

Reza Yazdani ◽

Mazdak Ganjalikhani-Hakemi ◽

Mohammad Esmaeili ◽

Hassan Abolhassani ◽

Shahram Vaeli ◽

...

Keyword(s):

B Cells ◽

Common Variable Immunodeficiency ◽

Akt Phosphorylation ◽

Common Variable

Download Full-text

Chemical chaperones reverse early suppression of regulatory circuits during unfolded protein response in B cells from common variable immunodeficiency patients

Clinical & Experimental Immunology ◽

10.1111/cei.13410 ◽

2020 ◽

Vol 200 (1) ◽

pp. 73-86 ◽

Author(s):

D. Bhatt ◽

R. C. Stan ◽

R. Pinhata ◽

M. Machado ◽

S. Maity ◽

...

Keyword(s):

B Cells ◽

Unfolded Protein Response ◽

Common Variable Immunodeficiency ◽

Chemical Chaperones ◽

Unfolded Protein ◽

Regulatory Circuits ◽

Protein Response ◽

Common Variable

Download Full-text

604 Phenotypic and Functional Analysis of B Cells in Patients with Common Variable Immunodeficiency

World Allergy Organization Journal ◽

10.1097/01.wox.0000411719.78493.55 ◽

2012 ◽

Vol 5 ◽

pp. S191

Author(s):

Laura Berrón-Ruiz ◽

Dolores Mogica Martínez ◽

Leopoldo Santos-Argumedo ◽

Gabriela López Herrera ◽

Francisco Espinosa-Rosales ◽

...

Keyword(s):

Functional Analysis ◽

B Cells ◽

Common Variable Immunodeficiency ◽

Common Variable

Download Full-text

F.85. Differences After Heterologous T Cell Dependent Costimulation in B Cells from Common Variable Immunodeficiency (CVID) Patients and Healthy Controls

Clinical Immunology ◽

10.1016/j.clim.2008.03.197 ◽

2008 ◽

Vol 127 ◽

pp. S71

Author(s):

Alejandra Vélez-Ortega ◽

Luisa Cardona ◽

Marcela Moncada ◽

José Franco

Keyword(s):

T Cell ◽

B Cells ◽

Common Variable Immunodeficiency ◽

Healthy Controls ◽

Common Variable

Download Full-text