Electrolyte Changes Associated with Pre-Infusion Washing of Bank Blood with The Hemonetics Cell Saver VÂ® During Liver Transplantation

PURPOSE: The aim of this study was to analyse the changes in transfusion requirements, in patients submitted to orthotopic liver transpantation from cadaveric donors, with the use of intraoperative red blood cell salvage (Cell Saver). METHODS: Data from 41 transplants were analysed. Intraoperative blood loss was calculated from the cell salvage, suction and the swabs. The autologous and heterologous transfusions were recorded The red blood salvage was performed using the Cell Saver 5 System (Haemonetics).. For analysis the patients were divided in two groups: one that used the Cell Saver and another that didn't. RESULTS: The median age of the patients was 50 years and the main indication for liver transplantation was cirrhosis (35 cases - 85.3%). The median blood loss was 8362 + 3994 ml (with the Cell Saver) and 10824 + 7002 ml (without the Cell Saver) and the median transfusion of heterologous packed red blood cells was 9,6 + 8 units (with the Cell Saver) compared to 22,3 + 21 units (without the Cell Saver). CONCLUSIONS: The Cells Saver has the potential to reduce the need for heterologous blood transfusion reducing the risks of transmissible diseases.

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Exchange Autotransfusion Using the Cell Saver during Liver Transplantation

Anesthesiology ◽

10.1097/00000542-198901000-00046 ◽

1989 ◽

Vol 70 (1) ◽

pp. 168-168 ◽

Cited By ~ 5

Author(s):

MARC R. BROWN ◽

MICHAEL A. E. RAMSAY ◽

THOMAS H. SWYGERT

Keyword(s):

Liver Transplantation ◽

Cell Saver

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Use of the Cell Saver during Elective Abdominal Aortic Aneurysm Surgery — Influence on Transfusion with Bank Blood. A Retrospective Survey

Anaesthesia and Intensive Care ◽

10.1177/0310057x9101900410 ◽

1991 ◽

Vol 19 (4) ◽

pp. 546-550 ◽

Cited By ~ 12

Author(s):

G. Brown ◽

M. Bookallil ◽

R. Herkes

Keyword(s):

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Aortic Surgery ◽

Operative Procedure ◽

Abdominal Aortic Aneurysm Repair ◽

Cell Saver ◽

Abdominal Aortic Surgery ◽

Abdominal Aortic ◽

Bank Blood ◽

Elective Abdominal Aortic Aneurysm

One hundred and two patients undergoing elective abdominal aortic aneurysm repair and admitted to ICU at RPAH in 1989/90 were studied. In forty patients a cell saver was used during the operative procedure (Group CS) while in the remaining sixty-two patients intraoperative blood loss was drained and discarded conventionally (Group NCS). Preoperative ASA grade and postoperative APACHE score were similar in these two groups. The amount of bank blood transfused intraoperatively was less in Group CS than in Group NCS (0.6 ±0.2 vs 3.3 ±0.3 units) (mean ± SEM) (P < 0.0001). The total amount of bank blood transfused during hospital admission was also less in Group CS (1.5 ± 0.4 vs 4.8 ± 0.4 units, P < 0.0001). Of Group CS, 22 patients (55%) received no bank blood compared to two patients (3%) in Group NCS. There was no difference between the groups with respect to postoperative haemoglobin and creatinine levels. ICU stay was similar in both groups. We conclude that use of the cell saver reduces perioperative bank blood transfusion in elective abdominal aortic surgery.

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Blood loss in orthotopic liver transplantation: a retrospective analysis of transfusion requirements and the effects of autotransfusion of cell saver blood in 164 consecutive patients

Blood Coagulation & Fibrinolysis ◽

10.1097/00001721-200004001-00017 ◽

2000 ◽

Vol 11 ◽

pp. S87-S93 ◽

Cited By ~ 52

Author(s):

H. G. D. Hendriks ◽

J. van der Meer ◽

I. J. Klompmaker ◽

N. Choudhury ◽

J. A. M. Hagenaars ◽

...

Keyword(s):

Liver Transplantation ◽

Blood Loss ◽

Retrospective Analysis ◽

Orthotopic Liver Transplantation ◽

Cell Saver ◽

Transfusion Requirements

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Role of spectrin in membrane fusion and in shape change of human erythrocyte ghost

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100082509 ◽

1978 ◽

Vol 36 (2) ◽

pp. 328-329

Author(s):

Hideo Hayashi ◽

Yoshikazu Hirai ◽

John T. Penniston

Keyword(s):

Conformational Changes ◽

Human Erythrocyte ◽

Shape Change ◽

Membrane Surface ◽

Slight Modification ◽

Active Role ◽

Main Role ◽

Bank Blood ◽

Human Erythrocyte Ghost

Spectrin is a membrane associated protein most of which properties have been tentatively elucidated. A main role of the protein has been assumed to give a supporting structure to inside of the membrane. As reported previously, however, the isolated spectrin molecule underwent self assemble to form such as fibrous, meshwork, dispersed or aggregated arrangements depending upon the buffer suspended and was suggested to play an active role in the membrane conformational changes. In this study, the role of spectrin and actin was examined in terms of the molecular arrangements on the erythrocyte membrane surface with correlation to the functional states of the ghosts.Human erythrocyte ghosts were prepared from either freshly drawn or stocked bank blood by the method of Dodge et al with a slight modification as described before. Anti-spectrin antibody was raised against rabbit by injection of purified spectrin and partially purified.

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