scholarly journals Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer (Russian Translation of Cochrane Plain Language Summary – PLS)

2021 ◽  
Vol 23 (2) ◽  
pp. 250-250

This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Lambin P, Ramaekers BLT, van Mastrigt GAPG, Van den Ende P, de Jong J, De Ruysscher DKM, Pijls-Johannesma M. Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.: CD006158. DOI: 10.1002/14651858.CD006158.pub2

2019 ◽  
Vol 128 (5) ◽  
pp. 441-446 ◽  
Author(s):  
Blake S. Raggio ◽  
Ryan D. Winters

Objective: The aim of this study was to summarize the effectiveness of steroids in the prevention of osteoradionecrosis of the head and neck. Data Sources: PubMED, MEDLINE, Embase, Google Scholar, and Cochrane trial registries. Methods: A systematic review of these data sources was performed through September 2018 using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Included were English-language studies evaluating patients of all age groups diagnosed with head and neck cancer who underwent radiation therapy while receiving peritreatment steroids compared with those who did not receive steroids. Results: Two retrospective cohort studies were identified for qualitative review. On the basis of analysis of 25 328 participants (36-82 years of age) with head and neck cancer who underwent radiation therapy, the use of peritreatment steroids was associated with a significantly lower risk for osteoradionecrosis in both studies, with a hazard ratio of 0.74 (95% confidence interval, 0.59-0.94; P = .012) and a relative risk of 0.04 (95% confidence interval, 0.003-0.560; P = .017). Meta-analysis was precluded by clinical and statistical heterogeneity. Overall, the studies were of limited quality with high risk for bias and poor methodology. Conclusions: Limited retrospective data suggest that steroids are predictive of a reduced risk for osteoradionecrosis; however, no definitive conclusions can be made given the poor quality of the available literature. Well-designed, comparison-controlled trials are needed to clarify the promising role of steroids in the prevention of osteoradionecrosis of the head and neck.


2021 ◽  
Vol 23 (3) ◽  
pp. 455-456

This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Ream E, Hughes AE, Cox A, Skarparis K, Richardson A, Pedersen VH, Wiseman T, Forbes A, Bryant A. Telephone interventions for symptom management in adults with cancer. Cochrane Database of Systematic Reviews 2020, Issue 6. Art. No.: CD007568. DOI: 10.1002/14651858.CD007568.pub2


2021 ◽  
Vol 23 (2) ◽  
pp. 251-251

This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Bohlius J, Schmidlin K, Brillant C, Schwarzer G, Trelle S, Seidenfeld J, Zwahlen M, Clarke MJ, Weingart O, Kluge S, Piper M, Napoli M, Rades D, Steensma D, Djulbegovic B, Fey MF, Ray-Coquard I, Moebus V, Thomas G, Untch M, Schumacher M, Egger M, Engert A. Erythropoietin or Darbepoetin for patients with cancer meta-analysis based on individual patient data. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.: CD007303. DOI: 10.1002/14651858.CD007303.pub2


2020 ◽  
Vol 22 (4) ◽  
pp. 45-46

This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Kahale LA, Hakoum MB, Tsolakian IG, Matar CF, Barba M, Yosuico VED, Terrenato I, Sperati F, Schnemann H, Akl EA. Oral anticoagulation in people with cancer who have no therapeutic or prophylactic indication for anticoagulation. Cochrane Database of Systematic Reviews 2017, Issue 12. Art. No.: CD006466. DOI: 10.1002/14651858.CD006466.pub6


Author(s):  
Philippe Lambin ◽  
Bram LT Ramaekers ◽  
Ghislaine APG van Mastrigt ◽  
P Van den Ende ◽  
J de Jong ◽  
...  

2014 ◽  
Vol 110 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Gustavo Nader Marta ◽  
Valter Silva ◽  
Heloisa de Andrade Carvalho ◽  
Fernando Freire de Arruda ◽  
Samir Abdallah Hanna ◽  
...  

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