scholarly journals The association of arterial hypertension and ischemic heart disease is the main problem in modern cardiology practice

2015 ◽  
Vol 12 (1) ◽  
pp. 70-75
Author(s):  
O D Ostroumova ◽  
V A Dudaev ◽  
V M Fomina
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Fixed Combination ◽  
Antihypertensive Drugs ◽  
Ischemic Heart ◽  
Actual Clinical Practice ◽  
Basic Characteristics

This article deals with the epidemiological datashowing higher frequency of arterial hypertension (AH) in patients with ischemic heart disease (IHD). We discussed the basic characteristics of modern domestic and foreign recommendations for treating patients with combination of AH and IHD. We showed the target of blood pressure (BP) in this category of patients. This article deals with the priority groups of antihypertensive drugs, which have the advantages in the combination usage in patients with association of these diseases. We fixed special attention to the problem of BP variability (BPV) as a new risk factor for the development of coronary complications in patients with AH. We showed the possibility of fixed combination of perindopril and amlodipine in reducing interand intervisit BPV in patients with AH and IHD in actual clinical practice.

scholarly journals Effect of Perindopril / Amlodipine Fixed Combination on Ultrasound Characteristics of Ventricles of the Heart in Patients with Ischemic Heart Disease and Arterial Hypertension

Kardiologiia ◽  
2019 ◽  
Vol 59 (1) ◽  
pp. 22-27 ◽  
Author(s):  
N. V. Drobotya ◽  
S. S. Torosyan ◽  
E. Sh. Guseynova ◽  
M. N. Morgunov
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Fixed Combination ◽  
Ischemic Heart ◽  
Fixed Dose ◽  
Significant Positive Effect ◽  
Dose Combination ◽  
Left And Right ◽  
Positive Effect

In a group of 32 patients with combined ischemic heart disease (IHD) and arterial hypertension (AH) we studied dynamics of parameters of blood pressure and ECG 24-hour monitoring, as well as ultrasound structural and functional parameters of left and right ventricles during 3-month therapy with fixed dose combination of perindopril arginine (10.0 mg) and amlodipine (5.0 mg). The obtained results demonstrated significant positive effect of this combination on the geometry, structure and diastolic function of both left and right ventricles, as well as confirmed its high antiischemic and antihypertensive effects.

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