Sodium hypochlorite (NaOCl) is a strong antiseptic agent that is usually used
as endodontic irrigant for dissolving organic parts of pulp and dentin and
neutralizing toxic products. However, the use of sodium hypochlorite may
cause destruction of blood vessels, soft tissues and bone necrosis if
extruded into the periapical region. Urgent treatment of the NaOCl accident
should be oriented on pain relief, infection control and recovery. This
paper shows a case of periradicular tissue necrosis after accidental
extrusion on NaOCl through fausse route of right maxillary canine, and
complete tissue regeneration after surgical debridement and bone
augmentation with addition of platelet rich fibrin (PRF) that occurred in a
53-year old patient at the dental clinic of Faculty of Dentistry in Pancevo.
Application of platelet rich fibrin in the treatment of ingival and bone necrosis following the use of paraformaldehyde containing devitalizing paste
