A randomized, prospective, comparative study to evaluate the motor blockade properties of 3ml of 0.5% isobaric levobupivacaine and 3ml of 0.5% isobaric ropivacaine for spinal anaesthesia in patients undergoing elective lower limb orthopaedic surgeries

Background: This is comparative study to differentiate the effects of Dexmedetomidine and clonidine on duration of analgesia, motor and sensory blockade and the intraoperative hemodynamic profile when mixed with Bupivacaine.Methods: Patients aged 15-45 years having ASA 1 and ASA 2 scheduled for elective orthopedic surgeries under spinal anaesthesia were included and divided into 3 groups equally (50 patients each)’ i.e. Group B received only 3.0 ml of 0.5% Bupivacaine (Heavy); Group C received 3.0ml of 0.5% Bupivacaine (Heavy) mixed with Clonidine 30 µg; and Group D administered with 3.0 ml of 0.5% Bupivacaine (Heavy) mixed with 5µg Dexmedetomidine.Results: Majority of the cases enrolled in the study were knee disorders and the rest being fracture femur, tibia. At preoperative interval mean systolic blood pressure and diastolic blood pressure of Group B was slightly higher than Group C and Group D. At the time when spinal anaesthesia was given, a slight fall in DBP of patients was observed in all Group B, Group C and Group D. Mean heart rate of patients at preoperative interval in patients of Group B, Group C and Group D respectively, with Group C and Group D showing slightly lower mean heart rate as compared with that of the mean heart rate of Group B but the values were not statistically significant. There were no any significant changes in the hemodynamic status.Conclusions: Both of used combinations provide prolonged sensory and motor blockade, hemodynamic stability, minimal side effects, and excellent intraoperative and postoperative analgesia.

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A comparative study between isobaric levobupivacaine and isobaric levobupivacaine with fentanyl in patients posted for lower abdominal and lower limb surgeries under spinal anaesthesia

Indian Journal of Clinical Anaesthesia ◽

10.18231/j.ijca.2019.086 ◽

2019 ◽

Vol 6 (3) ◽

pp. 446-449

Author(s):

Suma K.V ◽

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Santhosh K. Gouroji ◽

Praveen Kumar Katlinge ◽

◽

...

Keyword(s):

Comparative Study ◽

Spinal Anaesthesia ◽

Lower Limb

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Comparative study of onset and total time required for sensory and motor blockade of epidural ropivacaine with clonidine and dexmedetomidine for lower limb surgeries

International Journal of Medical Science and Public Health ◽

10.5455/ijmsph.2016.05102015204 ◽

2016 ◽

Vol 5 (7) ◽

pp. 1369

Author(s):

Shrirang Bamne ◽

Shrikrishna Bamne ◽

Shrikant Bamne

Keyword(s):

Comparative Study ◽

Lower Limb ◽

Motor Blockade ◽

Time Required

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Levobupivacaine versus racemic bupivacaine: a comparative study on spinal anaesthesia in lower limb surgeries

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20174558 ◽

2017 ◽

Vol 5 (10) ◽

pp. 4360

Author(s):

Arshad Imam ◽

Sabir Hasnat

Keyword(s):

Comparative Study ◽

Spinal Anaesthesia ◽

Lower Limb ◽

Cardiovascular Parameters ◽

Anaesthetic Potency ◽

Lower Limb Surgery

Background: This study aims to compare the anaesthetic potency of intrathecally administered levobupivacaine with racemic bupivacaine in lower limb surgeries.Methods: 60 adult cases ranging in age from 18 to 60 years with ASA Grade I and II, presenting for elective lower limb surgery were randomly allocated into two groups containing 30 cases each. Cases in Group L received 3ml of 0.5% levobupivacaine and those in Group R received 3ml of 0.5% levobupivacaine.Results: Cases in both groups showed similarity and no statistically significant differences were observed. Cardiovascular parameters were stable and similar between both groups.Conclusions: Levobupivacaine and racemic bupivacaine show equally effective potencies for spinal anaesthesia in lower limb surgeries.

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