Diagnostic role of mean platelet volume in cases presenting with thrombocytopenia in a tertiary health care setting of Puducherry

2019 ◽  
Vol 10 (3) ◽  
pp. 190-194
Author(s):  
J Jeya Shambavi ◽  
Thyroid ◽  
2020 ◽  
Vol 30 (9) ◽  
pp. 1280-1287 ◽  
Author(s):  
Tanya Chen ◽  
Brian M. Gilfix ◽  
Juan Rivera ◽  
Nader Sadeghi ◽  
Keith Richardson ◽  
...  

2020 ◽  
pp. 10-13
Author(s):  
◽  

Introduction: The aim of this study was to investigate the diagnostic role of mean platelet volume (MPV) for acute appendicitis. Methods: Patient files were retrospectively observed. MPV of 311 patients with pathological diagnosis of acute appendicitis were compared with the MPV of 314 healthy children (blood samples were taken for elective operations). SPSS (IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corp.) was used to evaluate the results. Results: 188 of acute appendicitis were male (%60.5). Mean age of acute appendicitis group was 10.22±3.83. MPV of children with the diagnosis of acute appendicitis (8.37±0.83fL) and the control group (10.55±0.83fL). MPV values were statistically different between the acute appendicitis and control group (p<0,001). Conclusion: MPV may be used as a marker for the diagnosis of acute appendicitis, but it is not a specific biomarker for appendicitis.


Author(s):  
Cláudia Febra ◽  
Ana Macedo

Background: Acute pulmonary embolism (PE) is the third most fatal cardiovascular disease. PE is frequently misdiagnosed due to its clinical presentation’s heterogeneity and the inexistence of biomarkers for its immediate diagnosis. Mean platelet volume (MPV) has shown a potential role as a biomarker in acute PE. In this analysis, we aimed to systematically compare the MPV in patients with and without definite diagnosis of PE, in emergency departments. Methods: Embase, PubMed and Medline were searched for relevant publications, in English. The main inclusion criteria were studies which compared MPV in patients with acute PEA versus a control group. Results: Thirteen studies consisting of a total number of 2428 participants were included. Of the participants included, 1316 were patients with confirmed acute PE, and 1112 were assigned to the control group. MPV was significantly higher in patients with acute PE than in controls (RR: 0.84, 95% CI: 0.76 – 0.92; P < .00001). There was a significant heterogeneity in the data. Conclusions: This analysis showed higher MPV to be associated with acute PE immediate diagnosis. These data show promise for the use of MPV as a readily available biomarker for the diagnosis of acute PE at the emergency department.


2017 ◽  
Vol 32 (6) ◽  
pp. 1075-1081 ◽  
Author(s):  
Şefika Elmas Bozdemir ◽  
Yasemin Ay Altıntop ◽  
Salih Uytun ◽  
Humeyra Aslaner ◽  
Yasemin Altuner Torun

2018 ◽  
Vol 132 (7) ◽  
pp. 615-618
Author(s):  
Y Nakao ◽  
T Tanigawa ◽  
F Kano ◽  
H Tanaka ◽  
N Katahira ◽  
...  

AbstractObjectiveTo assess the diagnostic role of mean platelet volume in tonsillitis with and without peritonsillar abscess.MethodsMean platelet volume and other laboratory data were retrospectively investigated.ResultsMean platelet volume was significantly lower in the tonsillitis group (7.8 per cent ± 0.7 per cent) than in the control group (8.7 per cent ± 0.6 per cent; p < 0.0001), and it was significantly lower in the abscess group (7.5 per cent ± 0.6 per cent) than in the no abscess group (8.0 per cent ± 0.7 per cent; p = 0.0277). White blood cell counts and C-reactive protein levels were not significantly different between patients with an abscess and those without. The mean platelet volume cut-off values for the diagnosis of tonsillitis and peritonsillar abscess were 7.95 fl and 7.75 fl, respectively.ConclusionOur results suggest that a decreased mean platelet volume is associated with the development and severity of tonsillitis. This finding provides useful diagnostic information for physicians treating patients with tonsillitis.


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