scholarly journals Patient specific instrumentation influences hemoglobin decrease after total knee replacement.

10.29007/f8h2 ◽  
2018 ◽  
Author(s):  
Davide Cucchi ◽  
Beatrice Zanini ◽  
Paolo Ferrua ◽  
Riccardo Compagnoni ◽  
Alessandra Menon ◽  
...  
Keyword(s):  
Blood Loss ◽  
Total Knee Replacement ◽  
Knee Replacement ◽  
Medullary Canal ◽  
Patient Specific ◽  
Reduce Blood Loss ◽  
Patient Specific Instrumentation ◽  
Significant Difference ◽  
Conventional Instrumentation ◽  
Total Knee

Patient Specific Instrumentation (PSI) may contribute to reduce blood loss after total knee replacement (TKR) by avoiding violation of the medullary canal. The purpose of the study was to compare the hemoglobin (Hb) decrease in two groups of patients undergoing TKR with PSI and conventional instrumentation.Pre- and post-operative blood samples were collected for twenty-two patients randomly assigned to receive a PSI-assisted or conventional TKR. Post- to preoperative Hb difference was calculated.A significant difference in Hb reduction in favor of the PSI group was registered on the last day of stay but not on the previous post-operative days: these promising results suggest a beneficial effect of PSI in blood loss reduction. PSI may hence be considered among the strategies available to control and reduce blood loss related to TKR.

Patient-Specific Instrumentation Affects Perioperative Blood Loss in Total Knee Arthroplasty

2018 ◽  
Vol 32 (06) ◽  
pp. 483-489 ◽  
Author(s):  
Davide Cucchi ◽  
Alessandra Menon ◽  
Beatrice Zanini ◽  
Riccardo Compagnoni ◽  
Paolo Ferrua ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Blood Loss ◽  
Knee Arthroplasty ◽  
Patient Specific ◽  
Significant Treatment ◽  
Longitudinal Measurements ◽  
Patient Specific Instrumentation ◽  
Significant Difference ◽  
Conventional Instrumentation ◽  
Total Knee

AbstractPatient-specific instrumentation (PSI) may contribute to reduced blood loss related to total knee arthroplasty (TKA). The purpose of this study was to compare the estimated hemoglobin (Hb) and red blood cell volume (RBC) losses in two groups of patients undergoing TKA with PSI and conventional instrumentation. Pre- and postoperative blood samples were collected from 22 patients randomly assigned to receive a PSI-assisted or conventional TKA. Post- to preoperative Hb difference was calculated and RBC loss was estimated according to Sehat et al. A significant difference in Hb reduction in favor of the PSI group was registered on the last day of stay (p = 0.0084) and significant treatment effect (p = 0.027) on Hb reduction after intervention was found with a regression model for longitudinal measurements. This study demonstrated that PSI leads to a significant trend in earlier Hb regain. These promising results suggest a beneficial effect of PSI in blood loss reduction.

Intra- and post-operative accuracy assessments of two different patient-specific instrumentation systems for total knee replacement

2013 ◽  
Vol 22 (3) ◽  
pp. 621-629 ◽  
Author(s):  
Andrea Ensini ◽  
Antonio Timoncini ◽  
Francesco Cenni ◽  
Claudio Belvedere ◽  
Francesca Fusai ◽  
...  
Keyword(s):  
Total Knee Replacement ◽  
Knee Replacement ◽  
Patient Specific ◽  
Patient Specific Instrumentation ◽  
Total Knee ◽  
Accuracy Assessments

scholarly journals The surgeon plays an important role in size planning with patient specific instrumentation for total knee replacement.

10.29007/g13b ◽  
2018 ◽  
Author(s):  
Davide Cucchi ◽  
Riccardo Compagnoni ◽  
Paolo Ferrua ◽  
Alessandra Menon ◽  
Pietro Randelli
Keyword(s):  
Total Knee Replacement ◽  
Knee Replacement ◽  
Patient Specific ◽  
Component Position ◽  
Careful Evaluation ◽  
Tibial Tray ◽  
Component Size ◽  
Patient Specific Instrumentation ◽  
Total Knee

Component position and sizing in total knee replacement (TKR) could be improved by patient specific instrumentation (PSI). The purpose of the study was to evaluate the reliability of the manufacturer plan in predicting final component sizes for TKR.Forty-five TKRs were prospectively enrolled and data on component size were recorded from the initial manufacturer’s proposal, the final plan modified after surgeon’s and from the actually implanted prostheses.Pre-operative modifications were required in more than 50% of the cases, with the tibial tray size requiring more frequent changes. The surgeon’s planning showed a significantly higher accuracy than the manufacturer’s one regarding tibial tray size (p < 0.05) but not femoral components size (p: n.s.). Careful evaluation by an experienced knee surgeon is recommended when planning TKR with PSI.

scholarly journals Evaluation of tranexamic acid in reducing blood loss and transfusions in total knee replacement

2019 ◽  
Vol 5 (5) ◽  
pp. 899
Author(s):  
Mirza Atif Baig ◽  
Srujith Kommera
Keyword(s):  
Blood Loss ◽  
Total Knee Replacement ◽  
Tranexamic Acid ◽  
Knee Replacement ◽  
Acid Group ◽  
Control Group ◽  
Blood Transfusions ◽  
Reduce Blood Loss ◽  
Transfusion Requirements ◽  
Total Knee

<p class="abstract"><strong>Background:</strong> Total knee replacement (TKR) is associated with substantial blood loss and thus the need for blood transfusions. Risks and costs of allogenic blood transfusions requires strategies to reduce blood loss in surgery. The objective of this study was to assess the efficacy of tranexamic acid treatment in reducing blood loss and blood transfusion requirements during TKR.</p><p class="abstract"><strong>Methods:</strong> A randomized controlled trial was conducted on 60 patients who were operated for unilateral TKR from January 2016 to January 2019 in Shadan Institute of Medical Sciences. 30 patients were in each control and study groups. In study group 12 mg/kg bolus of tranexamic acid was given as a slow IV dose, 40 minutes before deflation of tourniquet followed by 1.2 mg/kg/hr infusion for 12 hours with standard treatment of hospital and compared to the control group. Later blood loss was compared both intra and post operatively. Fall in haemoglobin after surgery was also compared.<strong></strong></p><p class="abstract"><strong>Results:</strong> Total blood loss in tranexamic acid group was 543.3±184.85<strong> </strong>ml (control group 685.83±176.74 ml) which is statistically significant (p&lt;0.05). Blood loss was markedly decreased in tranexamic acid group (379.16±174 ml in tranexamic acid vs. 513.33±143.89 ml in control group) statistically significant (p&lt;0.05).</p><p class="abstract"><strong>Conclusions:</strong> Tranexamic acid is an effective strategy to reduce blood loss in patients undergoing total knee replacement and thus minimizing the need for blood transfusions.</p>

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