scholarly journals Lobomicose

2017 ◽  
Vol 75 (3) ◽  
Author(s):  
FRANCISCO RONALDO MOURA RONALDO
Keyword(s):  
Lacazia Loboi ◽  
Lacazia Loboï

Resumo: Lobomicose ou Doença de Jorge Lobo é uma infecção crônica e granulomatosa, causada pela implantação traumática do fungo Lacazia loboi, que se restringe à pele. Típico de regiões tropicais e subtropicais; acomete, frequentemente, homens adultos ativos na floresta, além de ter sido diagnosticada em golfinhos. As lesões afetam principalmente áreas expostas da pele, tais como as aurículas e os membros superiores e inferiores e são tipicamente apresentadas como lesões queloides. A remoção cirúrgica é o procedimento terapêutico de escolha nos casos iniciais, enquanto itraconazol e clofazimina, isolados ou em associação, podem ser empregados para lesões disseminadas. 

scholarly journals DNA damage in BALB/c mice infected with Lacazia loboi and its relation to nutritional status

2015 ◽  
Vol 21 (1) ◽  
Author(s):  
Adriana Sierra Assencio Almeida Barbosa ◽  
Larissa Ragozo Cardoso de Oliveira ◽  
Francilene Capel Tavares ◽  
Carlos Roberto Gonçalves de Lima ◽  
Suzana Madeira Diório ◽  
...  
Keyword(s):  
Dna Damage ◽  
Nutritional Status ◽  
Lacazia Loboi ◽  
Lacazia Loboï

scholarly journals THE RELEVANCE OF NUTRITIONAL STATUS AND HISTOPATHOLOGICAL FINDINGS ON THE INFECTIOUS PROCESS OF BALB/C MICE INOCULATED WITH Lacazia loboi

2015 ◽  
Vol 57 (5) ◽  
pp. 421-426 ◽  
Author(s):  
Adriana Sierra Assencio Almeida BARBOSA ◽  
Suzana Madeira DIÓRIO ◽  
Silvia Cristina Barboza PEDRINI ◽  
Adauto José Ferreira NUNES ◽  
Andréa de Faria Fernandes BELONE ◽  
...  
Keyword(s):  
Great Influence ◽  
Giant Cells ◽  
The Body ◽  
Histopathological Analysis ◽  
Restricted Diet ◽  
Regular Diet ◽  
Protein Calorie Malnutrition ◽  
Large Numbers ◽  
Lacazia Loboi ◽  
Lacazia Loboï

SUMMARY The aim of this study was to evaluate the effects of the protein-calorie malnutrition in BALB/c isogenic mice infected with Lacazia loboi, employing nutritional and histopathological parameters. Four groups were composed: G1: inoculated with restricted diet, G2: not inoculated with restricted diet, G3: inoculated with regular diet, G4: not inoculated with regular diet. Once malnutrition had been imposed, the animals were inoculated intradermally in the footpad and after four months, were sacrificed for the excision of the footpad, liver and spleen. The infection did not exert great influence on the body weight of the mice. The weight of the liver and spleen showed reduction in the undernourished groups when compared to the nourished groups. The macroscopic lesions, viability index and total number of fungi found in the footpads of the infected mice were increased in G3 when compared to G1. Regarding the histopathological analysis of the footpad, a global cellularity increase in the composition of the granuloma was observed in G3 when compared to G1, with large numbers of macrophages and multinucleated giant cells, discrete numbers of lymphocytes were present in G3 and an increase was observed in G1. The results suggest that there is considerable interaction between Jorge Lobo's disease and nutrition.

scholarly journals Inoculation of BALB/c mice with Lacazia loboi

2000 ◽  
Vol 42 (5) ◽  
pp. 239-243 ◽  
Author(s):  
Suzana MADEIRA ◽  
Diltor Vladimir Araújo OPROMOLLA ◽  
Andréa de Faria Fernandes BELONE
Keyword(s):  
Disease Patient ◽  
Giant Cells ◽  
Post Inoculation ◽  
Therapeutic Evaluation ◽  
Before And After ◽  
Hind Foot ◽  
Lacazia Loboi ◽  
One Year ◽  
Lacazia Loboï ◽  
Fungal Suspension

In a previous study, the authors inoculated Swiss mice with Lacazia loboi (L. loboi) and succeeded in maintaining a granulomatous infiltrate and viable fungal cells up to one year and six months after inoculation. Considering the experimental work on paracoccidioidomycosis, 0.03 ml of a fungal suspension obtained from a biopsy of a Jorge Lobo's Disease patient were inoculated into both hind foot pads of 32 six week-old BALB/c mice of both sexes. The animals were sacrificed 1, 4, 7 and 10 months post inoculation. The suspension contained 1.3 x 10(6) fungi/ml and presented 38% viability. Seven months after inoculation, most of the animals presented profuse infiltrates consisting of isolated histiocytes, foreign body and Langhans' giant cells and a large number of fungi, most of them viable. Emergence of macroscopic lesions was observed during the 8th month. Based on fungal count, viability index before and after inoculation, presence of macroscopic lesions and histopathological findings similar to the findings in humans, the authors believe that BALB/c mice may be a good experimental model to study Jorge Lobo's Disease, mainly regarding therapeutic evaluation.

Lacazia loboi and Rhinosporidium seeberi: a genomic perspective

2005 ◽  
Vol 22 (4) ◽  
pp. 213-216 ◽  
Author(s):  
Leonel Mendoza ◽  
Raquel Vilela ◽  
Patricia S. Rosa ◽  
Andrea Faria Fernandes Belone
Keyword(s):  
Rhinosporidium Seeberi ◽  
Lacazia Loboi ◽  
Lacazia Loboï

Disseminated infection with Lacazia loboi and immunopathology of the lesional spectrum

2015 ◽  
Vol 46 (2) ◽  
pp. 334-338 ◽  
Author(s):  
Francisca Regina Oliveira Carneiro ◽  
Thais Rodrigues da Cunha Fischer ◽  
Caroline Martins Brandão ◽  
Carla Pagliari ◽  
Maria Irma Seixas Duarte ◽  
...  
Keyword(s):  
Disseminated Infection ◽  
Lacazia Loboi ◽  
Lacazia Loboï

scholarly journals Lacaziose simulando hanseníase dimorfa tuberculóide

2008 ◽  
Vol 83 (3) ◽  
pp. 261-263 ◽  
Author(s):  
Liana Hortência Miranda Tubilla ◽  
Antônio Pedro Mendes Schettini ◽  
Josie da Costa Eiras ◽  
Claudia Zanardo Alves da Graça ◽  
Maria Zeli Moreira Frota
Keyword(s):  
Lacazia Loboi ◽  
Lacazia Loboï

Lacaziose é infecção crônica causada pelo fungo Lacazia loboi, originalmente descrita por Jorge Lobo (1931) em paciente oriundo da Amazônia brasileira. Manifesta-se, sobretudo, por lesões cutâneas queloidiformes. Relata-se o caso de paciente com placa eritêmato-violácea, cuja hipótese diagnóstica inicial foi de hanseníase dimorfa tuberculóide, doença também endêmica na região amazônica. Ressalta-se a importância da inclusão de formas paucibacilares de hanseníase no diagnóstico diferencial da lacaziose.

scholarly journals Lacaziosis: Micosis cutánea profunda, reporte de un caso

2015 ◽  
Vol 5 (3) ◽  
Author(s):  
Silvia Riggioni Víquez ◽  
Silvia Díaz Araya
Keyword(s):  
Lacazia Loboi ◽  
Lacazia Loboï

<p>La lacaziosis es una rara micosis cutánea y subcutánea, de evolución crónica, ocasionada por el hongo profundo Lacazia loboi. Ha sido descrita principalmente en regiones tropicales y subtropicales.Clínicamente se caracteriza por lesiones cutáneas de aspecto queloideano y progresión lenta. La enfermedad se presenta más frecuentemente en adultos varones que desempeñan actividades laborales en el campo. Se presenta el caso de un paciente masculino de 68 años, agricultor, con una dermatosis crónica localizada en el miembro superior derecho, caracterizada por una neoformación compuesta por múltiples lesiones nodulares de aspecto queloideano con una lesión satélite proximal. El diagnóstico histopatológico fue compatible con una lacaziosis</p>

scholarly journals Lobomicose

2010 ◽  
Vol 85 (2) ◽  
pp. 239-240 ◽  
Author(s):  
Carolina Talhari ◽  
Renata Rabelo ◽  
Lisiane Nogueira ◽  
Mônica Santos ◽  
Anette Chrusciak-Talhari ◽  
...  
Keyword(s):  
Lacazia Loboi ◽  
Lacazia Loboï

Caso de lobomicose em paciente procedente da região amazônica brasileira. Essa micose subcutânea, causada pela levedura Lacazia loboi, acomete, frequentemente, homens adultos e foi também diagnosticada em golfinhos. O tratamento depende da apresentação clínica: letrocoagulação, exérese cirúrgica e crioterapia são opções terapêuticas para as lesões localizadas, como a do paciente relatado, enquanto itraconazol e clofazimina, isolados ou em associação, podem ser empregados para lesões disseminadas. Até o presente, não há tratamento adequado para os casos com lesões disseminadas.

Comparative morphology of Lacazia loboi (syn. Loboa loboi) in dolphins and humans

2000 ◽  
Vol 38 (1) ◽  
pp. 9-14 ◽  
Author(s):  
E. M. Haubold ◽  
C. R. Cooper ◽  
J. W. Wen ◽  
M. R. McGinnis ◽  
D. F. Cowan
Keyword(s):  
Comparative Morphology ◽  
Lacazia Loboi ◽  
Lacazia Loboï
Sign in / Sign up

Export Citation Format

Share Document