scholarly journals The Need for Societal Investment to Improve Cervical Cancer Outcomes in Nigeria: A commentary

2017 ◽  
Vol 21 (4) ◽  
pp. 17-23 ◽  
Author(s):  
Jonah Musa
Keyword(s):  
Cervical Cancer ◽  
Cancer Outcomes

scholarly journals EP-1777: Cervical cancer outcomes in the high-doserate brachytherapy era: A single institution experience

2017 ◽  
Vol 123 ◽  
pp. S977
Author(s):  
N. Alyamani ◽  
G. Bhattacharya ◽  
R. Samant ◽  
C. E ◽  
T. Le ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Outcomes ◽  
Single Institution

scholarly journals Distance from a Comprehensive Cancer Center: A proxy for poor cervical cancer outcomes?

2016 ◽  
Vol 143 (3) ◽  
pp. 617-621 ◽  
Author(s):  
David A. Barrington ◽  
Sarah E. Dilley ◽  
Emily E. Landers ◽  
Eric D. Thomas ◽  
Jonathon D. Boone ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Cancer Outcomes

Cervical cancer outcomes in true cut through simple hysterectomy compared to appropriately managed controls

2019 ◽  
Vol 154 ◽  
pp. 113
Author(s):  
T. Castellano ◽  
L. Driskill ◽  
A. Rodriguez ◽  
M.A. Gold ◽  
L.M. Landrum
Keyword(s):  
Cervical Cancer ◽  
Cancer Outcomes

scholarly journals Cervical Cancer Outcomes in Women Living With HIV in the Age of Anti-Retroviral Therapy

2020 ◽  
Vol 108 (3) ◽  
pp. e466
Author(s):  
A.K. Yoder ◽  
S. Wang ◽  
D. Roque ◽  
C.H. Son ◽  
M.S. Ludwig ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Outcomes ◽  
Women Living With Hiv ◽  
Living With Hiv

Primary chemoradiation therapy for locally advanced cervical cancer: Outcomes and disparities

2019 ◽  
Vol 154 (1) ◽  
pp. e31-e32
Author(s):  
T. Korenaga ◽  
W. Pierson ◽  
M. Swanson ◽  
J. Chapman ◽  
L. Chen
Keyword(s):  
Cervical Cancer ◽  
Locally Advanced ◽  
Chemoradiation Therapy ◽  
Advanced Cervical Cancer ◽  
Cancer Outcomes ◽  
Locally Advanced Cervical Cancer

Impact of hypoxia on cervical cancer outcomes

2021 ◽  
pp. ijgc-2021-002806
Author(s):  
Anubhav Datta ◽  
Catharine West ◽  
James P B O'Connor ◽  
Ananya Choudhury ◽  
Peter Hoskin
Keyword(s):  
Cervical Cancer ◽  
Developed Countries ◽  
Response Monitoring ◽  
Prevention Measures ◽  
Cancer Outcomes ◽  
Middle Income ◽  
Distant Relapse ◽  
Incidence And Mortality ◽  
New Treatment ◽  
Meta Analyses

The annual global incidence of cervical cancer is approximately 604 000 cases/342 000 deaths, making it the fourth most common cancer in women. Cervical cancer is a major healthcare problem in low and middle income countries where 85% of new cases and deaths occur. Secondary prevention measures have reduced incidence and mortality in developed countries over the past 30 years, but cervical cancer remains a major cause of cancer deaths in women. For women who present with Fédération Internationale de Gynécologie et d’Obstétrique (FIGO 2018) stages IB3 or upwards, chemoradiation is the established treatment. Despite high rates of local control, overall survival is less than 50%, largely due to distant relapse. Reducing the health burden of cervical cancer requires greater individualization of treatment, identifying those at risk of relapse and progression for modified or intensified treatment. Hypoxia is a well known feature of solid tumors and an established therapeutic target. Low tumorous oxygenation increases the risk of local invasion, metastasis and treatment failure. While meta-analyses show benefit, many individual trials targeting hypoxia failed in part due to not selecting patients most likely to benefit. This review summarizes the available hypoxia-targeted strategies and identifies further research and new treatment paradigms needed to improve patient outcomes. The applications and limitations of hypoxia biomarkers for treatment selection and response monitoring are discussed. Finally, areas of greatest unmet clinical need are identified to measure and target hypoxia and therefore improve cervical cancer outcomes.

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