Emerging Non-Canonical Small-Molecule Inhibitors of Androgen Receptor (AR) and AR Interactome Partners for the Treatment of Castrate-Resistant Prostate Cancer

Inhibition of the Androgen Receptor Amino-Terminal Domain by a Small Molecule as Treatment for Castrate-Resistant Prostate Cancer

10.21236/ada590496 ◽

2013 ◽

Author(s):

Stephen R. Plymate

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Amino Terminal ◽

Terminal Domain ◽

Castrate Resistant ◽

Amino Terminal Domain

Abstract 1575: Novel small molecule inhibitors of p300/CBP down-regulate AR and c-Myc for the treatment of castrate resistant prostate cancer

10.1158/1538-7445.am2017-1575 ◽

2017 ◽

Cited By ~ 1

Author(s):

Nigel Brooks ◽

Neil Pegg ◽

Jenny Worthington ◽

Barbara Young ◽

Amy Prosser ◽

...

Keyword(s):

Prostate Cancer ◽

Small Molecule ◽

Abstract B091: Small-molecule inhibitors targeting a specific metabolic pathway for precision therapy of advanced castrate-resistant prostate cancer

10.1158/1538-7445.prca2017-b091 ◽

2018 ◽

Author(s):

Hirak Basu ◽

Nathaniel Wilganowski ◽

Jessica Lieblich ◽

Grace Wu ◽

Izabela Fokt ◽

...

Keyword(s):

Prostate Cancer ◽

Small Molecule ◽

Metabolic Pathway ◽

Precision Therapy ◽

Inhibition of the Androgen Receptor Amino-Terminal Domain by a Small Molecule as Treatment for Castrate-Resistant Prostate Cancer

10.21236/ada609928 ◽

2014 ◽

Author(s):

Stephen R. Plymate

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Amino Terminal ◽

Terminal Domain ◽

Castrate Resistant ◽

Amino Terminal Domain

Small-molecule inhibitors of the Serum Response Factor in combination with enzalutamide: New strategy to treat castrate-resistant prostate cancer

European Urology Open Science ◽

10.1016/s2666-1683(21)01196-4 ◽

2021 ◽

Vol 32 ◽

pp. O10

Author(s):

H. Azam ◽

S. Maher ◽

S. Marcone ◽

M. Prencipe

Keyword(s):

Prostate Cancer ◽

Small Molecule ◽

Serum Response Factor ◽

Response Factor ◽

New Strategy ◽

Castrate Resistant ◽

Serum Response

Inhibition of the Androgen Receptor Amino-Terminal Domain by a Small Molecule as Treatment for Castrate-Resistant Prostate Cancer

10.21236/ada566784 ◽

2012 ◽

Author(s):

Stephen R. Plymate

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Amino Terminal ◽

Terminal Domain ◽

Castrate Resistant ◽

Amino Terminal Domain

Clinical pharmacology profile of an oral selective androgen receptor down-regulator, AZD3514: Implications on the design of ongoing castrate-resistant prostate cancer clinical studies

Cancer Research Frontiers ◽

10.17980/2016.330 ◽

2016 ◽

Vol 2 (3) ◽

pp. 330-351

Author(s):

Angela Dymond ◽

◽

Marc-Antoine Fabre ◽

Gareth James ◽

Masako Hirata ◽

...

Keyword(s):

Prostate Cancer ◽

Clinical Pharmacology ◽

Androgen Receptor ◽

Clinical Studies ◽

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance ◽

Development of novel androgen receptor inhibitors to overcome castrate-resistant prostate cancer

10.1016/b978-0-12-821310-0.00007-3 ◽

2021 ◽

pp. 23-46

Author(s):

Hilal Saraç ◽

Artem Cherkasov ◽

Nathan A. Lack

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Abstract 148: Glucocorticoid receptor-mediated cell survival following androgen receptor blockade in castrate-resistant prostate cancer

10.1158/1538-7445.am2012-148 ◽

2012 ◽

Cited By ~ 1

Author(s):

Kristen Otto ◽

Don Vander Griend ◽

Suzanne Conzen ◽

Russell Szmulewitz

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Glucocorticoid Receptor ◽

Cell Survival ◽

Receptor Blockade ◽

Abstract 2924: Constitutively active androgen receptor splice variants function independently of full-length androgen receptor in a cell-based model of castrate-resistant prostate cancer

10.1158/1538-7445.am2012-2924 ◽

2012 ◽

Cited By ~ 10

Author(s):

Peter E. Lonergan ◽

Lucas P. Nacusi ◽

Lucy J. Schmidt ◽

Kevin M. Regan ◽

Furkan U. Ertem ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variants ◽

Full Length ◽

A Cell ◽

Castrate Resistant ◽

Androgen Receptor Splice Variants ◽

Constitutively Active