AbstractAlzheimer’s disease is the most common form of dementia. The aim of this study was to determine thedependence between the quality of the caregiver-patient relationship and the psychological costs the caregiver bearsduring the caregiving period. This study encompassed 292 caregivers (104 partners, 117 children and 71 friends or otherspersons).The study indicated the greatest level of depression and caregiving-related burdens in the spouses group, and the leastin the friends/others group. The most important predictor of the level of burden in the caregiving role turned out to bethe nature of the caregiver-patient relationship; however, a varying set of the significance of individual elements of thisrelationship were indicated in different caregiver groups.