scholarly journals Solitary Langerhans Cell Histiocytosis of Skull: Case Report with One-year Follow-up

2021 ◽  
Vol 31 (08) ◽  
pp. 989-991
2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
E. Roos ◽  
M. Maas ◽  
S. J. M. Breugem ◽  
G. R. Schaap ◽  
J. A. M. Bramer

Nonbacterial osteitis is a rare autoinflammatory disease. Often it is mistaken for a tumor or osteomyelitis. We present a case of a twelve-year-old girl referred to our hospital because of a lesion of the right clavicle. The differential diagnoses were sarcoma, osteitis, and Langerhans cell histiocytosis. After biopsy the diagnosis nonbacterial osteitis (NBO) was established. Treatment of choice is a nonsteroidal anti-inflammatory drug. This case report gives a complete follow-up of the disease, showing the pitfalls of the diagnosis.


2014 ◽  
Vol 80 (4) ◽  
pp. 366-367 ◽  
Author(s):  
Emeline das Neves de Araújo Lima ◽  
Eliakim Medeiros Alves de Araújo ◽  
Patrícia Teixeira de Oliveira ◽  
Ana Miryam Costa de Medeiros

2019 ◽  
Vol 13 (1) ◽  
pp. 17
Author(s):  
Dinny Gustina Prihadi ◽  
Agung Firmansyah Sumantri ◽  
Hasyarati Agustina ◽  
Indra Wijaya

Background: Langerhans Cell Histiocytosis (LCH) is a disease characterized by proliferation and infiltration of histiocytes in various organs that is caused by local or systemic effects. LCH could affect bones, lungs, central nervous system, liver, thymus, skin, and lymph nodes. The diagnosis of LCH is difficult to enforce and rarely found in adults, namely 1-2 cases per million per year.Case Presentation: In Indonesia, there were very few cases of LCH in adults, one of which was found in women aged 56 years. LCH does not yet have standard treatments. The treatment is given based on location and severity, including intralesional corticosteroid injection, radiotherapy, surgical or excision curettage, and chemotherapy. Prednisone and vinblastine chemotherapy was one of chemotherapy that is given to LCH patients. Prognosis of LCH consists of various factors, one of which is the number of organs involved. This is a case report of LCH in an adult male patient with skin involvement who received chemotherapy for 6 weeks and experienced improvement.Conclusions: LCH is not only a disease of children; it is also reported in an adult. The prognosis is related to the number of organ involved and involvement of the risk organ. LCH can recur easily and accompany malignant tumors, so follow-up and long-term observations are still needed to be done.


2015 ◽  
Vol 17 (12) ◽  
Author(s):  
Hamidreza Haghighatkhah ◽  
Yousef Jafroodi ◽  
Morteza Sanei Taheri ◽  
Ramin Pourghorban ◽  
Afarin Sadeghian Dehkordy

2015 ◽  
Vol 8 (3) ◽  
pp. 426-431 ◽  
Author(s):  
Toru Udaka ◽  
Michiro Susa ◽  
Kazutaka Kikuta ◽  
Kazumasa Nishimoto ◽  
Keisuke Horiuchi ◽  
...  

Langerhans cell histiocytosis (LCH) usually occurs in children under the age of 10 years with a predilection for the skull, spine, rib and humerus. Solitary LCH occurring in an adult clavicle is uncommon with limited reports to date. The lesion in our patient was curetted with the intent to make a diagnosis, which subsequently lead to the remission of the symptom and the disease. At the final follow-up after 1 year, no local recurrence or metastasis is observed.


2016 ◽  
Vol 9 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Sung Hyun Kim ◽  
Moon Young Choi

Single-site, single-system Langerhans cell histiocytosis (LCH) of the rib is one of the rarest causes of bone tumor in adults. Herein, we report a case of a healthy 35-year-old male who presented with upper back pain that was attributed to a solitary osteolytic lesion at the posterolateral aspect of his sixth rib. For diagnostic confirmation and treatment, partial resection of the sixth rib was performed and pathologic finding was consistent with LCH. At the final follow-up after 2 years, no local recurrence or metastasis was observed.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110579
Author(s):  
Anne-Sophie Smilga ◽  
Mona Lavoie ◽  
Sungmi Jung ◽  
Ariane Schreiber

Necrobiotic xanthogranuloma is a rare non-Langerhans cell histiocytosis with a known association with monoclonal gammopathies and malignant conditions. There is a lack of consensus regarding the management of necrobiotic xanthogranuloma. In this case report, the patient is diagnosed with a long-standing necrobiotic xanthogranuloma limited to the skin. Although all initial investigations were reassuring, the patient remains at a higher risk of developing a malignant condition. The goal of the authors is to highlight the need for clearer investigation and follow-up guidelines.


2021 ◽  
pp. 112067212199767
Author(s):  
Iva Krolo ◽  
Aida Kasumović ◽  
Ivana Radman ◽  
Pavao Pavić

Purpose: Ocular features of Alport syndrome include anterior lenticonus, posterior polymorphous corneal dystrophy, and fleck-and-dot retinopathy in most cases. Keratoconus in such patients has been rarely mentioned in previous studies. To our knowledge, this is the first report of corneal cross-linking for halting the progression of keratoconus in a patient with Alport syndrome. Case report: A 22-year-old male was referred for his initial corneal topography, after he was already prescribed with rigid gas-permeable contact lenses. Alport syndrome was diagnosed in his infancy and gene COL4A5 mutation was confirmed. Ophthalmological evaluation confirmed keratoconus. One-year follow-up showed a progression on his right eye and standard corneal cross-linking was performed. Stabilization of the disease marked by normalization in visual function and corneal tomography values was noticed 1 year after the procedure. Conclusions: When diagnosing ocular clinical findings of Alport syndrome, keratoconus should be considered. Standard corneal cross-linking protocol can halt its progression.


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