scholarly journals Relationship between Hemoglobin A1c and Fractional Flow Reserve Lesion Severity in Non-diabetic Patients

2022 ◽  
Vol 32 (1) ◽  
pp. 4-8
Keyword(s):  
Fractional Flow Reserve ◽  
Hemoglobin A1c ◽  
Diabetic Patients ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Lesion Severity

scholarly journals The relationship between coronary stenosis morphology and fractional flow reserve: a computational fluid dynamics modelling study

2021 ◽  
Author(s):  
Roberto T F Newcombe ◽  
Rebecca C Gosling ◽  
Vignesh Rammohan ◽  
Patricia V Lawford ◽  
D Rodney Hose ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Fractional Flow Reserve ◽  
Computational Modelling ◽  
Fractional Flow ◽  
Cfd Modelling ◽  
Flow Reserve ◽  
The Relationship ◽  
Lesion Severity

Abstract Background International guidelines mandate the use of fractional flow reserve (FFR) and/or non-hyperaemic pressure ratios to assess the physiological significance of moderate coronary artery lesions to guide revascularisation decisions. However, they remain underused such that visual estimation of lesion severity continues to be the predominant decision-making tool. It would be pragmatic to have an improved understanding of the relationship between lesion morphology and haemodynamics. Aims To compute virtual FFR (vFFR) in idealised coronary artery geometries with a variety of stenosis and vessel characteristics Methods Coronary artery geometries were modelled, based upon physiologically realistic branched arteries. Common stenosis characteristics were studied, including % narrowing, length, eccentricity, shape, number, position relative to branch, and distal (myocardial) resistance. Computational fluid dynamics (CFD) modelling was used to calculate vFFRs using the VIRTUheartTM system. Results Percentage lesion severity had the greatest effect upon FFR. Any ≥80% diameter stenosis in two views (i.e. concentric) was physiologically significant (FFR ≤ 0.80), irrespective of length, shape or vessel diameter. Almost all eccentric stenoses and all 50% concentric stenoses were physiologically non-significant, whilst 70% uniform concentric stenoses about 10mm long straddled the ischaemic threshold (FFR 0.80). A low microvascular resistance (MVR) reduced FFR on average by 0.05, and a high MVR increased it by 0.03. Conclusions Using computational modelling, we have produced an analysis of virtual FFR that relates stenosis characteristics to haemodynamic significance. The strongest predictor of a positive virtual FFR was a concentric, ≥80% diameter stenosis. The importance of MVR was quantified. Other lesion characteristics have a limited impact.

The delta fractional flow reserve can predict lesion severity and long-term prognosis

2009 ◽  
Vol 203 (1) ◽  
pp. 178-184 ◽  
Author(s):  
Sinan Altan Kocaman ◽  
Asife Sahinarslan ◽  
Uğur Arslan ◽  
Timur Timurkaynak
Keyword(s):  
Fractional Flow Reserve ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Long Term Prognosis ◽  
Lesion Severity

Clinical Outcomes of Deferred Revascularisation Using Fractional Flow Reserve in Diabetic Patients

2020 ◽  
Vol 21 (7) ◽  
pp. 897-902 ◽  
Author(s):  
Mohammad Alkhalil ◽  
Claire McCune ◽  
Lisa McClenaghan ◽  
Jonathan Mailey ◽  
Patrick Collins ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Fractional Flow Reserve ◽  
Diabetic Patients ◽  
Fractional Flow ◽  
Flow Reserve

scholarly journals TCT-385 Diagnostic Performance of Noninvasive Fractional Flow Reserve derived from Computed Tomography in Diabetic Patients

2018 ◽  
Vol 72 (13) ◽  
pp. B155-B156
Author(s):  
Shinichiro Sakurai ◽  
Hiroaki Takashima ◽  
Akihiro Suzuki ◽  
HIroaki Sawada ◽  
Hirohiko Ando ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Fractional Flow Reserve ◽  
Diagnostic Performance ◽  
Diabetic Patients ◽  
Fractional Flow ◽  
Flow Reserve

scholarly journals Recent myocardial infarction does not limit the utility of fractional flow reserve for the physiologic assessment of lesion severity

2003 ◽  
Vol 41 (6) ◽  
pp. 61 ◽  
Author(s):  
John C. McClish ◽  
Michael Ragosta ◽  
Eric R. Powers ◽  
Gregory A. Bishop ◽  
Joshua Fischer ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Fractional Flow Reserve ◽  
Fractional Flow ◽  
Recent Myocardial Infarction ◽  
Flow Reserve ◽  
Lesion Severity

scholarly journals 1120-64 High left ventricular mass does not limit the utility of fractional flow reserve for the physiologic assessment of lesion severity

2004 ◽  
Vol 43 (5) ◽  
pp. A76
Author(s):  
Adnan K Chhatriwalla ◽  
Kurt G Barringhaus ◽  
Michael Ragosta ◽  
Eric R Powers ◽  
J.Christopher McClish ◽  
...  
Keyword(s):  
Left Ventricular Mass ◽  
Fractional Flow Reserve ◽  
Left Ventricular ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Ventricular Mass ◽  
Lesion Severity
Sign in / Sign up

Export Citation Format

Share Document