scholarly journals VENTRICULAR TACHYCARDIA

2007 ◽  
Vol 14 (04) ◽  
pp. 556-561
Author(s):  
MUHAMMAD SHAH GILANI ◽  
Abrar Ahmad Khan ◽  
ABDUL SATTAR ◽  
Arif Rahim Khan ◽  
QAISER MAHMOOD

Introduction: Frequent or complex patterns of ventricular ectopic activity,whether occurring during routine activity or induced by exercise, are often a marker for serious heart disease and aharbinger of sudden death. The detection of such arrhythmias is thus an important responsibility of the physician.Objective: To find the prevalence, associated characteristics and prognostic significance of exercise induced nonsustainedVT in a representative population. Material and Methods: Setting: Nishtar Hospital, Multan. Sample size:1000 patients. Duration: Two years. Study design: Descriptive, analytical study. Sampling Technique: Convenientprobability sampling done. Results: Ten subjects, 7 men and 3 women, with exercise induced VT were identified,representing 1.1% of those tested; only 1 was young than 65 years. All episodes of VT were asymptomatic and nonsustained.In 9 of 10 subjects, VT developed at or near peak exercise. The longest run of VT was 6 beats; multiple runsof VT were present in 4 subjects. Two subjects had exercise induced ST segment depression, but subsequent exercisethallium scintigraphic results were negative in each. Compared with a group of age and sex matched control subjects,those with asymptomatic, non-sustained VT displayed no difference in exercise duration, maximal heart rate, or theprevalence of coronary risk factors or exercise induced ischemia as measured by electrocardiography and thalliumscintigrahy. Over a mean follow period of 2 years, no subject has developed symptoms of heart disease or experiencedsyncope or sudden death. Thus, exercise induced VT in apparently healthy subjects occurs almost exclusively in theelderly, is limited to short, asymptomatic runs of 3 to 6 beats usually near peak exercise, and does not portendincreased cardiovascular morbidity or mortality rates over a 2 year period of observation. Conclusion: Exerciseinduced VT in apparently healthy subjects occurs almost exclusively in the elderly, is limited to short, asymptomaticruns of 3 to 6 beats usually near peak exercise, and does not show increased cardiovascular morbidity or mortalityrates over a 2 year period of observation.

Author(s):  
Rafel Cirer-Sastre ◽  
Francisco Corbi ◽  
Isaac López-Laval ◽  
Luis Enrique Carranza-García ◽  
Joaquín Reverter-Masià

To examine the exercise-induced release of cardiac troponin T (cTnT) in adolescent and adult swimmers. Thirty-two trained male (18 adolescents, 14 adults) swam at maximal pace in a 45 min distance trial, and blood samples were drawn before, immediately and 3 h after exercise for subsequent cTnT analysis and comparison. Having comparable training experience and baseline values of cTnT (p = 0.78 and p = 0.13), adults exercised at lower absolute and relative intensity (p < 0.001 and p < 0.001, respectively), but presented higher immediate cTnT after exercise than adolescents (p < 0.001). Despite that, peak concentrations were observed at 3 h post exercise and peak elevations were comparable between groups (p = 0.074). Fourteen (44%) apparently healthy subjects exceeded the cutoff value for myocardial infarction (MI). Adolescents presented a delayed elevation of cTnT compared with adults, but achieved similar peak values.


1994 ◽  
Vol 76 (1) ◽  
pp. 230-235 ◽  
Author(s):  
H. Perrault ◽  
B. Melin ◽  
C. Jimenez ◽  
G. Dureau ◽  
P. Dureau ◽  
...  

Orthotopic heart transplantation results in cardiac denervation that can disrupt the normal regulation of hydromineral balance. This study compared the exercise-induced variations in plasma osmolality; atrial natriuretic peptide (ANP), arginine vasopressin (AVP), norepinephrine (NE), epinephrine (E), and dopamine (DA) concentrations; and plasma renin activity (PRA) of six cardiac transplant recipients (HTX) and six healthy age-matched controls (C) submitted to graded upright maximal cycling. Venous blood samples were obtained at rest, at submaximal (70% O2 uptake) and peak exercise, and after 10 and 30 min of sitting recovery. Peak O2 uptake was not different between groups despite lower maximal heart rate in HTX (136 +/- 6 vs. 183 +/- 9 beats/min). Baseline plasma ANP and PRA were higher in HTX (203 +/- 55 pg/ml and 29.9 +/- 7.4 ng.ml-1 x h-1) than in C (71 +/- 17 pg/ml and 5.4 +/- 0.96 ng.ml-1 x h-1); AVP was lower in HTX than in C (1.1 +/- 0.3 vs. 3.2 +/- 0.8 pg/ml; P < 0.05); and circulating E, NE, and DA were not different between groups. Exercise resulted in more marked increases in HTX than in C for ANP (300 vs. 100%), AVP (2,000 vs. 300%), NE (860 vs. 500%), and DA (611 vs. 187%) but not for PRA and a higher E response in C than in HTX (455 vs. 1,258%). These observations confirm that the potential for ANP release to central volume loading is independent of intact cardiac innervation. The exaggerated AVP response in HTX could, however, reflect the absence of inhibitory influences consecutive to denervation.(ABSTRACT TRUNCATED AT 250 WORDS)


1995 ◽  
Vol 25 (2) ◽  
pp. 87A-88A
Author(s):  
Jerome L. Fleg ◽  
Alan B. Zonderman ◽  
Lewis C. Becker ◽  
Steven P. Schulman ◽  
Gary Gerstenblith ◽  
...  

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Federica Re ◽  
Geza Halasz ◽  
Francesco Moroni ◽  
Matteo Beltrami ◽  
Pasquale Baratta ◽  
...  

Abstract Aims Pulmonary arterial hypertension (PAH) has been described in patients with hypertrophic cardiomyopathy (HCM) and it was associated with a worse prognosis. Nevertheless in most HCM patients, despite normal pulmonary pressures at rest, congestive symptoms are elicited by exercise. In the present study, combining cardiopulmonary exercise test (CPET) with echocardiography, we aimed to evaluate the presence of exercise-induced pulmonary hypertension (EiPAH) its role in functional limitation and its prognostic significance in a cohort of patients with obstructive and non-obstructive HCM. Methods and results 182 HCM patients (35% females, mean age 47.5 ± 15.9) undergoing CPET. During CPET, LVOT velocities and trans-tricuspid gradient were measured. Thirty-seven patients (20%) developed sPAP &gt; 40 mmHg at peak exercise (EiPAH). EiPAH was associated with an lower exercise performance, larger left atrial volumes, higher left ventricular gradient and higher VE/VCO2 slope .At multivariable model baseline sPAP (P &lt; 0.0001) and baseline left ventricular obstruction (LVOT) (P = 0.028) were significantly associated with EiPAH .Kaplan-Meier curve analysis showed EiPAH was a significant predictor of HCM –related morbidity (hazards ratio: 6.21, 95% CI: 1.47–26.19; P = 0.05; 4.21, 95% CI: 1.94–9.12; P &lt; 0.001) for the primary and the secondary endpoint respectively. Conclusions EiPAH was present in about one fifth of HCM patients without evidence of elevated pulmonary pressures at rest, and was associated with adverse clinical outcome. Diagnosing EiPAH by exercise echo/CPET may help physicians to detect early stage of PAH requiring a closer clinical monitoring and individualized treatment strategies.


1984 ◽  
Vol 25 (2) ◽  
pp. 155-166
Author(s):  
Joji ANDO ◽  
Hisakazu YASUDA ◽  
Atsushi MIYAMOTO ◽  
Takeshi KOBAYASHI ◽  
Hirotaka NISHIJIMA ◽  
...  

1999 ◽  
Vol 83 (3) ◽  
pp. 371-375 ◽  
Author(s):  
Thomas G Allison ◽  
Marco A.S Cordeiro ◽  
Todd D Miller ◽  
Hiroyuki Daida ◽  
Ray W Squires ◽  
...  

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