scholarly journals CHRONIC LIVER DISEASE (CLD);

2012 ◽  
Vol 19 (03) ◽  
pp. 351-355
Author(s):  
SHAHZAD ALAM KHAN ◽  
TARIQ MUHAMMAD KHAN TAREEN ◽  
IJAZ-UL- HAQUE TASEER ◽  
SOHAIL Safdar
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Upper Gastrointestinal Bleeding ◽  
Case Series ◽  
Personal Data ◽  
Chronic Liver ◽  
Upper Gi ◽  
Male Patients ◽  
Gi Bleed ◽  
Upper Gastrointestinal

Objective: To determine the frequency of chronic liver disease in patients presenting with upper gastrointestinal bleeding(UGIB) at Nishtar Hospital, Multan. Study Design: Descriptive case series. Duration of study: Six months from August 2009 to January 2010.Setting: Department of Internal Medicine, Nishtar Hospital Multan. Methodology: A total of 88 patients with upper GI bleed were registered.Prior permission was taken from Institutional Ethical Committee to conduct this study. Informed consent was taken from each patient. Upper GIEndoscopy was done to find out the source of bleeding. For identification of each patient, personal data was collected. All the data collectedwere entered and analyzed using SPSS-10. Results: Mean age was 41.64±13.56 years with 49 (55.70%) male patients and 39 (44.30%)female patients. Majority of the patients 38(43.18%) were between 36-50 years of age. In our series frequency of chronic liver disease was56.82%. Conclusions: Chronic liver disease is the most common cause of upper GI bleeding in our setting.

scholarly journals Hepatic encephalopathy in chronic liver disease; predisposing factors in a developing country

2014 ◽  
Vol 6 (2) ◽  
pp. 35-42 ◽  
Author(s):  
Fakhar Ali Qazi Arisar ◽  
Shameem Behram Khan ◽  
Anam Umar
Keyword(s):  
Liver Disease ◽  
Hepatic Encephalopathy ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Electrolyte Imbalance ◽  
Normal Brain ◽  
Cross Sectional ◽  
Medical Unit ◽  
Upper Gi ◽  
Gi Bleed

Objective: To find out the risk factors for developing Hepatic Encephalopathy in patients suffering from Chronic liver disease.Background: Hepatic encephalopathy (HE) is a neuropsychiatric disorder that is caused by liver damage.  In its pathology, alterations in normal brain function are associated with an increase in blood ammonia, benzodiazepine like substances, products of neurotoxic fatty acids, and other gut derived toxins, which gain access to the brain as a result of liver dysfunction. Study Design: Hospital based descriptive, cross sectional study. Setting: Medical Unit 1, Ward- 5, Jinnah Post Graduate Medical Centre, Karachi.Duration:  July 2013 to December 2013Patients and Methods: About 150 patients admitted in medical unit 1 with a diagnosis of chronic liver disease in a state of hepatic encephalopathy were included in this study. Patients suffering from viral or bacterial encephalitis, stroke, brain tumor, Wernicke’s encephalopathy were excluded from the study.Results and Observations: There were 96 (64%) female and 54 (36%) were male patients. Mean age of the patients was 52.45 (±12.271) years. 80 (53.33%) patients were having constipation. Infection was found in 55 (36.66%) cases. Upper GI Bleed was present in 51 (34%) patients. 44 (29.33%) patients had moderate to severe electrolyte imbalance as the cause. Constipation alone was the cause in 11.33% of cases. More than one factor was found to be responsible in around 56% of patients while in 6.6% of cases none of these precipitating factors was isolated.Conclusion: Constipation is the commonest cause of hepatic encephalopathy followed by infection, upper GI bleed and electrolyte imbalance.DOI: http://dx.doi.org/10.3126/ajms.v6i2.11099Asian Journal of Medical Sciences Vol.6(2) 2015 36-43

CHRONIC LIVER DISEASE; FREQUENCY OF NON VARICEAL UPPER GASTROINTESTINAL BLEEDING IN THE PATIENTS

2016 ◽  
Vol 23 (02) ◽  
pp. 204-208
Author(s):  
Dr. Ahsan Mobin ◽  
Dr. Fawed Qureshi ◽  
Dr. Darshan Kumar ◽  
Dr. Hussain Haroon ◽  
Dr. Rakhshinda Jabeen
Keyword(s):  
Liver Disease ◽  
Gastrointestinal Bleeding ◽  
Chronic Liver Disease ◽  
Upper Gastrointestinal Bleeding ◽  
Chronic Liver ◽  
Upper Gastrointestinal

CHRONIC LIVER DISEASE

2016 ◽  
Vol 23 (02) ◽  
pp. 204-208
Author(s):  
Ahsan Mobin ◽  
Fawed Qureshi ◽  
Darshan Kumar ◽  
Hussain Haroon ◽  
Rakhshinda Jabeen
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Cross Sectional Study ◽  
Chronic Liver ◽  
Cross Sectional ◽  
Upper Gi ◽  
Cirrhotic Patients ◽  
Medical Wards ◽  
Gi Bleed ◽  
Disease Study

Objectives: To determine the frequency of non variceal upper gastrointestinalbleeding in the patients of chronic liver disease. Study Design: Cross sectional study. Placeand Duration of Study: All medical wards of Civil Hospital and Ojha campus, Dow Universityof Health Sciences, Karachi, Pakistan from May 2013 to January 2015. Methodology: A total of267 patients of chronic liver disease (CLD) who presented with upper GI bleed (hematemesis ormelena) were included in this study. Before the endoscopic procedures, patients were clinicallyevaluated by gastroenterology fellows at the time of patient’s presentation. Upper GI endoscopywas performed within 48 hours in all hemodynamically stable patients. Results: The averageage of the patients was 44.27±12.13 years. Frequency of non variceal upper gastrointestinalbleeding (NVUGIB) in the patients of chronic liver disease was 56.93% (152/167). Conclusion:It is concluded that current magnitude of NVUGIB is very high in cirrhotic patients thereforeadequate planning and knowledge of the specific mechanisms explaining the prognosticfactors of NVUGIB to prevent it and thereby reducing the morbidity and mortality in ChronicLiver Disease.

scholarly journals Upper Gi Endoscopy-indications and Findings at Tertiary Care Hospital Hyderabad/Jamshoro

2021 ◽  
pp. 46-50
Author(s):  
Jalpa Devi ◽  
Muhammad Akram Bajwa ◽  
Nasrullah Aamer ◽  
Rabia Farooque ◽  
Hira Laghari ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Esophageal Varices ◽  
Chronic Liver ◽  
Care Hospital ◽  
Gi Endoscopy ◽  
Endoscopic Findings ◽  
Upper Gi ◽  
Upper Gi Endoscopy ◽  
Gi Bleed

Objective: To document different indications and findings of upper GI Endoscopy in our endoscopy suite. Methods: A descriptive study of 500 patients who underwent upper gastrointestinal (UGI) endoscopy was conducted in the Endoscopy Unit of PNS DRIGH LUMHS Jamshoro and Civil Hospital Hyderabad from April to September 2020. Included patients underwent UGI endoscopy. Demographic data including indications and endoscopic findings of the patients was collected via study proforma. Results: Total five hundred patients were studied; their mean age was 42.4±16.8 years. Out of all 52.8% were males. Upper GI bleed was the commonest indication (33.2%) followed by dysphagia (21.6%), epigastrium pain (10%), surveillance and screening of varices (9% and 8.2% respectively).  The most common endoscopic findings were esophageal varices (32.2 %), gastritis (18.8%), and normal (11.4%). In patients with esophageal varices, 77.4% had chronic liver disease with positive serology for HCV and HBV in 63.4% and 23% respectively. Conclusion: The most common indication was upper GI bleed with esophageal varices for upper GI endoscopy. The underlying etiology of varices reflects the high burden of chronic liver disease due to viral hepatitis.

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