LASIK;

Objectives: To determine the effect of LASIK on tear film stability. Study Design:Cross sectional, prospective study. Setting: The study was conducted in D. G. Laser Vision andDiagnostic Center, D.G. Khan, South Punjab, Pakistan. Period: From March 2016 to September2016. Materials and Methods: One hundred patients (two hundred eyes) were selected forthis study. SPSS version 20 was used to analyze the data. Categorical variables presented asfrequency and percentages and numerical variables presented as mean ± standard deviation.Results: It is observed that values of tear break up time, Schimer I and Schimer II were decreasingat one week and one month post LASIK as compare to one week pre LASIK values. Mean tearbreak up time at one week of pre LASIK was 14.72 ± 1.08 seconds (P=0.000), at one week postLASIK was 13.64 ± 1.507 seconds (P=0.000) and at one month post LASIK was 13.02 ± 1.695seconds (P=0.000). Conclusion: Laser in situ keratomileusis (LASIK) significantly changestear film stability and tear secretions for at least one month post operatively.