scholarly journals Effects of Non-Surgical Periodontal Therapy on Gingival Crevicular Fluid Levels of Interleukin-17 and Interleukin-23 in Patients with Periodontitis: A Clinical Trial

2020 ◽  
Vol 32 (3) ◽  
pp. 75-82
Author(s):  
Maryam Haghi ◽  
Mandana Sattari ◽  
Fereshteh Shanei ◽  
Ferial Taleghani ◽  
◽  
...  
Keyword(s):  
Clinical Trial ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Interleukin 17 ◽  
Interleukin 23 ◽  
Crevicular Fluid ◽  
Fluid Levels

Gingival crevicular fluid levels of MMP-8, MMP-9, TIMP-2, and MPO decrease after periodontal therapy

2010 ◽  
Vol 37 (2) ◽  
pp. 180-190 ◽  
Author(s):  
Andrea M. Marcaccini ◽  
Cesar A. Meschiari ◽  
Leonardo R. Zuardi ◽  
Tiago Sampaio de Sousa ◽  
Mario Taba ◽  
...  
Keyword(s):  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Crevicular Fluid ◽  
Fluid Levels

scholarly journals Non-Surgical Periodontal Therapy with Adjunctive Amoxicillin/Metronidazole or Metronidazole When No Aggregatibacter actinomycetemcomitans Is Detected—A Randomized Clinical Trial

Antibiotics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 686
Author(s):  
Holger F. R. Jentsch ◽  
Martin Dietrich ◽  
Sigrun Eick
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Gingival Crevicular Fluid ◽  
Aggregatibacter Actinomycetemcomitans ◽  
Periodontal Therapy ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Crevicular Fluid ◽  
Systemic Antibiotics ◽  
Attachment Level

Background: The aim was to compare two different systemic antibiotics regimens adjunctive to non-surgical periodontal therapy when Aggregatibacter actinomycetemcomitans was not detected in the subgingival biofilm. Methods: A total of 58 patients with periodontitis and with no A. actinomycetemcomitans in the subgingival biofilm were treated with full-mouth subgingival instrumentation and either metronidazole (MET; n = 29) or amoxicillin/metronidazole (AMX/MET; n = 29). Probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were recorded at baseline, as well as after three and six months. Subgingival biofilm and gingival crevicular fluid were collected and analyzed for major periodontopathogens and biomarkers. Results: PD, CAL and BOP improved at 3 and 6 months (each p < 0.001 vs. baseline) with no difference between the groups. Sites with initial PD ≥ 6 mm also improved in both groups after 3 and 6 months (p < 0.001) with a higher reduction of PD in the AMX/MET group (p < 0.05). T. forsythia was lower in the AMX/MET group after 3 months (p < 0.05). MMP-8 and IL-1β were without significant changes and differences between the groups. Conclusion: When A. actinomycetemcomitans was not detected in the subgingival biofilm, the adjunctive systemic use of amoxicillin/metronidazole results in better clinical and microbiological outcomes of non-surgical periodontal therapy when the application of systemic antibiotics is scheduled.

The Gingival Crevicular Fluid Levels of Interleukin-11 and Interleukin-17 in Patients With Aggressive Periodontitis

2012 ◽  
Vol 83 (11) ◽  
pp. 1425-1431 ◽  
Author(s):  
Zuhal Yetkin Ay ◽  
Gülin Yılmaz ◽  
Muhsin Özdem ◽  
Havva Koçak ◽  
Recep Sütçü ◽  
...  
Keyword(s):  
Gingival Crevicular Fluid ◽  
Aggressive Periodontitis ◽  
Interleukin 17 ◽  
Crevicular Fluid ◽  
Fluid Levels ◽  
Interleukin 11
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