Features of the Postoperative Period in Patients with Chronic Dacryocystitis and Type 2 Diabetes Mellitus after Endoscopic Endonasal Dacryocystorhinostomy Depending on the Degree of Compensation of Diabetes Mellitus

Author(s):  
Pavlo A. Bezditko ◽  
Nina M. Bezega

The aim. To identify the features of the postoperative period in patients with chronic dacryocystitis and type 2 diabetes mellitus (DM2) after endoscopic endonasal dacryocystorhinostomy (DCR), depending on the degree of compensation of DM. Materials and methods. The study involved 30 DM2 patients with chronic dacryocystitis who underwent endoscopic endonasal DCR according to standard methods. The patients were divided into groups according to the degree of compensation of DM2: 6 patients with compensated, 7 patients with subcompensated and 17 patients with decompensated DM2. The results of the operation were evaluated after 2 months, 6 months and 2 years. In addition to standard methods, ophthalmic examination included nasolacrimal duct probing, lacrimal duct lavage, and endoscopic examination of the nasal cavity. Results and discussion. The efficiency of endoscopic endonasal DCR in decompensated DM2 after 2 months (58.8 ± 11.9 % of patients) on average was 1.4 times, and after 6 months (52.9 ± 12.1 % of patients) and 2 years (41.2 ± 11,9 % of patients) – it was 1.5 times less than that in subcompensated and compensated DM2 (p < 0.05). In patients with decompensated DM2, tearing was observed in 41.2 ± 11.9 % of patients after 2 months, in 47.1 ± 12.1 % of patients after 6 months and in 58.8 ± 11.9 % of patients after 2 years post-op, which was, on average, 2.7 times, 2.1 times and 1.5 times more often than that in subcompensated and compensated DM2, respectively (p < 0.05); there were no significant differences between the values (p > 0.05). Conclusions. Features of the postoperative period in patients with chronic dacryocystitis after endoscopic endonasal DCR depend on the degree of compensation of DM2. The efficiency of endoscopic endonasal DCR in decompensated DM2 after 2 months is on average 1.4 times, and after 6 months and 2 years it is 1.5 times less than that in subcompensated and compensated DM2. Keywords: type 2 diabetes mellitus, degree of compensation of diabetes mellitus, chronic dacryocystitis, efficiency of endoscopic endonasal dacryocystorhinostomy, features of postoperative period.

2010 ◽  
Vol 56 (1) ◽  
pp. 9-13
Author(s):  
A V Pokrovskiĭ ◽  
R M Doguzhieva ◽  
V S Demidova ◽  
A N Lebedeva

The objective of the present study was to compare levels of homocysteine (HC), total cholesterol (TC), triglycerides, high and low density lipoproteins (HDLP and LDLP respectively), and C-reactive protein (CRP) and to evaluate their role in the development of atherosclerosis in patients with type 2 diabetes mellitus (DM2) or without it in the late postoperative period following aortofemoral reconstructive (AFR) operations. A total of 79 patients (40 with DM2 and 39 without it) examined after AFR surgery had the above parameters enhanced compared with the respective baseline values. In the majority of the cases, hyperhomocysteinemia (HHC) was associated with the increased levels of CRP, fibrinogen, and LDLP. However, they were higher in patients with DM2 than without it and correlated with the HbA1c level (r=0.32-0.45; p<0.05). In DM2 patients with HHC, simultaneous hyperlipidemia and elevated CRP levels, the thickness of the intima-media complex in aorta, popliteal artery, anterior and posterior tibial arteries significantly increased. Moreover, these patients experienced more apparent stenosis of these arteries (>50%). Patients with DM2 more frequently exhibited a combination of several markers of the atherosclerotic process especially in the presence of the smouldering inflammatory process in the vascular wall.


2016 ◽  
Vol 29 (3) ◽  
pp. 176
Author(s):  
Isabel Brandão ◽  
Ana Marques Pinho ◽  
Filipa Arrojado ◽  
Ana Pinto-Bastos ◽  
José Maia Da Costa ◽  
...  

<p><strong>Introduction:</strong> Obesity is associated with a great number of complications, including type 2 diabetes mellitus and psychiatric pathology. Bariatric surgery is the best solution to weight loss and improvement of complications in morbid obese patients. This study aims to analyze the evolution of type 2 diabetes mellitus and psychopathologic variables before and after bariatric surgery and assess the importance of different variables in weight loss.<br /><strong>Material and Methods:</strong> This is a longitudinal study, which evaluates 75 patients before and after bariatric surgery (47 - LAGB – laparoscopic adjustable gastric band; 19 – RYGB – Roux-en-Y gastric bypass; 9 - sleeve) with a follow-up time between 18 and 46 months. A clinical interview and self report questionnaires were applied - Eating Disorder Examination questionnaire – EDE-Q and Beck Depression Inventory – BDI.<br /><strong>Results:</strong> Results show an improvement in type 2 diabetes mellitus after surgery (χ2 (1) = 26.132, p &lt; 0.001). There was not a significant improvement among psychiatric pathology when we controlled the analysis for the type of surgery. It was verified that type 2 diabetes mellitus, depression and eating disorders in post-operative period are associated with less weight loss. This model explains 27% of weight variance after surgery (R2 = 0.265) and it is significant F (3.33) = 2.981, p = 0.038.<br /><strong>Discussion:</strong> Type 2 diabetes mellitus, psychiatric pathology and eating disorders after surgery influenced weight loss. It was not clear in what way this relation was verified, neither the relation that these metabolic and psychological variables may have during the postoperative period.<br /><strong>Conclusion:</strong> Type 2 diabetes mellitus improved after surgery. Type 2 diabetes mellitus, depression and eating disorders influenced weight loss in the postoperative period. These variables did not influence weight loss in the preoperative period.</p>


2020 ◽  
Vol 33 ◽  
Author(s):  
Ariana de Melo Tosta ◽  
Marisa de Carvalho Borges ◽  
Élida Mara Carneiro da Silva ◽  
Alex Augusto da Silva ◽  
Eduardo Crema

Abstract Introduction: The lung is considered a target organ in diabetes mellitus as a consequence of alterations secondary to chronic hyperglycemia that compromise respiratory muscle strength. Metabolic surgery for improving diabetes mellitus has beneficial effects on weight loss and glucose metabolism. Objective: The objective of this study was to evaluate the respiratory muscle strength, assessed by MIP and MEP, body mass index (BMI) and fasting glucose profile of patients with type 2 diabetes mellitus before and after metabolic surgery without gastric resection. Method: Seventeen patients with type 2 diabetes mellitus participated in the study. The participants had a mean age of 44.8 ± 11.81 years. Results: The results showed a significant decrease of MEP values in the immediate postoperative period when compared to the preoperative period (p=0.001), while no significant results were obtained for MIP. Regarding BMI and fasting glucose, significant weight loss and a significant reduction in fasting glucose levels were observed in the late postoperative period (p=0.006 and p=0.007, respectively). Conclusion: The MIP and MEP were reestablished and satisfactory results were obtained for BMI and fasting glucose in the late postoperative period. Further studies are needed to monitor patients in the pre- and postoperative period of metabolic surgery, identifying complications and acting on the care and recovery of these patients.


2015 ◽  
Vol 21 ◽  
pp. 280-281
Author(s):  
Medha Munshi ◽  
Jasvinder Gill ◽  
Jason Chao ◽  
Elena Nikonova ◽  
Andreas Stuhr ◽  
...  

2015 ◽  
Vol 21 ◽  
pp. 106
Author(s):  
Franco Grimaldi ◽  
Laura Tonutti ◽  
Claudia Cipri ◽  
Cecilia Motta ◽  
Maria Antonietta Pellegrini ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document