Distortion-product Otoacoustic Emissions in Middle-aged Subjects with Normal versus Potentially Presbyacusic High-frequency Hearing Loss

Purpose The aim of this study was to measure the effect of tinnitus, while accounting for the effect of hearing loss and aging, on distortion product otoacoustic emissions (DPOAEs). Method DPOAEs were measured twice in both ears in 5 groups of participants: young adults with normal hearing, middle-age adults with normal hearing, adults with high-frequency sensorineural hearing loss, age-matched adults with similar hearing loss and tinnitus, and adults with normal hearing and chronic tinnitus. Results Multivariate analysis revealed a main effect of hearing loss and age, but no effect of tinnitus, across all 5 groups. Separate tests revealed significant effects of age and tinnitus in the normal-hearing groups and hearing loss in adults with or without tinnitus, but no effect of tinnitus in those with hearing loss. Conclusion DPOAE levels in the group of adults with hearing loss and tinnitus were diminished, but those in the group with normal hearing and tinnitus were enhanced, relative to DPOAE levels in the controls. Outer hair cell function, as indexed by DPOAEs, exhibits a complex association with tinnitus, and this has implications in the use of DPOAEs as a tool both for testing for tinnitus presence and for creating a model of neural mechanisms underlying tinnitus.

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Distortion-Product Otoacoustic Emissions in Humans with High Frequency Sensorineural Hearing Loss

Journal of Speech Language and Hearing Research ◽

10.1044/jshr.3303.594 ◽

1990 ◽

Vol 33 (3) ◽

pp. 594-600 ◽

Cited By ~ 49

Author(s):

F. P. Harris

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

High Frequency ◽

Otoacoustic Emissions ◽

Sensorineural Hearing ◽

Distortion Product Otoacoustic Emissions ◽

Distortion Product

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Relationship Between Distortion Product Otoacoustic Emissions and Hearing Loss

Perspectives on Audiology ◽

10.1044/poa2.1.2 ◽

2006 ◽

Vol 2 (1) ◽

pp. 2-9

Author(s):

Tiffany A. Johnson ◽

Stephen T. Neely ◽

Michael P. Gorga

Keyword(s):

Hearing Loss ◽

Otoacoustic Emissions ◽

Distortion Product Otoacoustic Emissions ◽

Distortion Product

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Effect of mastoid drilling on hearing of the contralateral ear

The Journal of Laryngology & Otology ◽

10.1017/s0022215113001965 ◽

2013 ◽

Vol 127 (10) ◽

pp. 952-956 ◽

Cited By ~ 6

Author(s):

A Goyal ◽

P P Singh ◽

A Vashishth

Keyword(s):

Hearing Loss ◽

High Frequency ◽

Otoacoustic Emissions ◽

Pure Tone Audiometry ◽

Otoacoustic Emission ◽

Prospective Clinical Study ◽

Distortion Product Otoacoustic Emission ◽

High Frequencies ◽

Distortion Product ◽

Contralateral Ear

AbstractObjectives:This study aimed to: understand the effect that high intensity noise associated with drilling (during otological surgery) has on hearing in the contralateral ear; determine the nature of hearing loss, if any, by establishing whether it is temporary or persistent; and examine the association between hearing loss and various drill parameters.Methods:A prospective clinical study was carried out at a tertiary centre. Thirty patients with unilateral cholesteatoma and normal contralateral hearing were included. Patients were evaluated pre-operatively and for five days following surgery using high frequency pure tone audiometry, and low and high frequency transient evoked and distortion product otoacoustic emission testing.Results:The findings revealed statistically significant changes in distortion product otoacoustic emissions at high frequencies (p = 0.016), and in transient evoked otoacoustic emissions at both low and high frequencies (p = 0.035 and 0.021, respectively). There was a higher statistical association between otoacoustic emission changes and cutting burrs compared with diamond burrs.Conclusion:Drilling during mastoid surgery poses a threat to hearing in the contralateral ear due to noise and vibration conducted transcranially.

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Early Changes in Auditory Function As a Result of Platinum Chemotherapy: Use of Extended High-Frequency Audiometry and Evoked Distortion Product Otoacoustic Emissions

Journal of Clinical Oncology ◽

10.1200/jco.2006.07.9723 ◽

2007 ◽

Vol 25 (10) ◽

pp. 1190-1195 ◽

Cited By ~ 114

Author(s):

Kristin R. Knight ◽

Dale F. Kraemer ◽

Christiane Winter ◽

Edward A. Neuwelt

Keyword(s):

High Frequency ◽

Otoacoustic Emissions ◽

Distortion Product Otoacoustic Emissions ◽

Auditory Function ◽

Cochlear Function ◽

Serial Measurement ◽

Distortion Product ◽

High Frequency Audiometry ◽

Platinum Based Chemotherapy ◽

Platinum Chemotherapy

Purpose The objective is to describe progressive changes in hearing and cochlear function in children and adolescents treated with platinum-based chemotherapy and to begin preliminary evaluation of the feasibility of extended high-frequency audiometry and distortion product otoacoustic emissions for ototoxicity monitoring in children. Patients and Methods Baseline and serial measurement of conventional pure-tone audiometry (0.5 to 8 kHz) and evoked distortion product otoacoustic emissions (DPOAEs) were conducted for 32 patients age 8 months to 20 years who were treated with cisplatin and/or carboplatin chemotherapy. Seventeen children also had baseline and serial measurement of extended high-frequency (EHF) audiometry (9 to 16 kHz). Audiologic data were analyzed to determine the incidence of ototoxicity using the American Speech-Language-Hearing Association criteria, and the relationships between the different measures of ototoxicity. Results Of the 32 children, 20 (62.5%) acquired bilateral ototoxicity in the conventional frequency range during chemotherapy treatment, and 26 (81.3%) had bilateral decreases in DPOAE amplitudes and dynamic range. Of the 17 children with EHF audiometry results, 16 (94.1%) had bilateral ototoxicity in the EHF range. Pilot data suggest that EHF thresholds and DPOAEs show ototoxic changes before hearing loss is detected by conventional audiometry. Conclusion EHF audiometry and DPOAEs have the potential to reveal earlier changes in auditory function than conventional frequency audiometry during platinum chemotherapy in children.

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Relationship Between Distortion Product – Otoacoustic Emissions (DPOAEs) and High-Frequency Acoustic Immittance Measures

Medical Science Monitor ◽

10.12659/msm.897157 ◽

2016 ◽

Vol 22 ◽

pp. 2028-2034 ◽

Cited By ~ 1

Author(s):

Ualace De Paula Campos ◽

Stavros Hatzopoulos ◽

Lech K. Śliwa ◽

Piotr H. Skarżyński ◽

Wiesław W. Jędrzejczak ◽

...

Keyword(s):

High Frequency ◽

Otoacoustic Emissions ◽

Distortion Product Otoacoustic Emissions ◽

Distortion Product

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Hearing Screening of Newborns using Distortion Product Otoacoustic Emissions

Bengal Journal of Otolaryngology and Head Neck Surgery ◽

10.47210/bjohns.2021.v29i2.478 ◽

2021 ◽

Vol 29 (2) ◽

pp. 189-195

Author(s):

Vybhavi MK ◽

Srinivas V

Keyword(s):

Hearing Loss ◽

Otoacoustic Emissions ◽

Screening Tool ◽

Hearing Screening ◽

Distortion Product Otoacoustic Emissions ◽

Profound Hearing Loss ◽

Distortion Product ◽

Lost To Follow Up ◽

Evoked Response Audiometry

Introduction The present study was devised to estimate the prevalence of neonatal hearing loss and document the importance of using DPOAE as a screening tool for identifying hearing loss in newborns. Materials and Methods This hospital based descriptive study was conducted from August 2018 to August 2019. A total of 928 newborn babies were included in the study. These newborn babies were subjected to hearing screening by distortion product otoacoustic emissions (DPOAE) at 24-72 hrs after birth. For pass cases, no further testing was done. For refer cases, repeat testing with DPOAE was done within 15-30 days. Newborns with refer result on repeat DPOAE testing were subjected to Brainstem evoked response audiometry (BERA) within 3 months to confirm hearing loss. Results Nine hundred and twenty eight newborn babies were screened by DPOAE. 851 newborns passed the first DPOAE hearing screening and 77 newborns gave refer result. 21 newborns were lost to follow-up. 56 newborns underwent repeat DPOAE testing and 5 newborns were referred for BERA. Amongst the 5 newborns who underwent BERA testing, one newborn was diagnosed with bilateral profound hearing loss. Hence, the prevalence of hearing loss of 1.08 per thousand newborn babies was estimated in this study. Conclusion Hearing screening of newborns using DPOAE followed by BERA in refer cases to confirm hearing loss is useful for early detection followed by timely intervention and rehabilitation.

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