Effect of Tinnitus on Distortion Product Otoacoustic Emissions Varies With Hearing Loss

2013 ◽  
Vol 22 (1) ◽  
pp. 125-134 ◽  
Author(s):  
Fatima T. Husain
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Otoacoustic Emissions ◽  
Outer Hair Cell ◽  
Cell Function ◽  
Normal Hearing ◽  
Neural Mechanisms ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product ◽  
Main Effect

Purpose The aim of this study was to measure the effect of tinnitus, while accounting for the effect of hearing loss and aging, on distortion product otoacoustic emissions (DPOAEs). Method DPOAEs were measured twice in both ears in 5 groups of participants: young adults with normal hearing, middle-age adults with normal hearing, adults with high-frequency sensorineural hearing loss, age-matched adults with similar hearing loss and tinnitus, and adults with normal hearing and chronic tinnitus. Results Multivariate analysis revealed a main effect of hearing loss and age, but no effect of tinnitus, across all 5 groups. Separate tests revealed significant effects of age and tinnitus in the normal-hearing groups and hearing loss in adults with or without tinnitus, but no effect of tinnitus in those with hearing loss. Conclusion DPOAE levels in the group of adults with hearing loss and tinnitus were diminished, but those in the group with normal hearing and tinnitus were enhanced, relative to DPOAE levels in the controls. Outer hair cell function, as indexed by DPOAEs, exhibits a complex association with tinnitus, and this has implications in the use of DPOAEs as a tool both for testing for tinnitus presence and for creating a model of neural mechanisms underlying tinnitus.

Early Evidence of Cochlear Damage in a Large Sample of Percussionists

2005 ◽  
Vol 20 (3) ◽  
pp. 135-139
Author(s):  
Jodee A Pride ◽  
David R Cunningham
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Otoacoustic Emissions ◽  
Outer Hair Cell ◽  
Cell Damage ◽  
Normal Hearing ◽  
Outer Hair Cells ◽  
Sensory Loss ◽  
Distortion Product ◽  
Hair Cell Damage

Percussionists can be exposed to intermittent sound stimuli that exceed 145 dB SPL, although damage may occur to the outer hair cells at levels of 120 dB SPL. The present study measured distortion-product otoacoustic emissions (DPOAEs) in a group of 86 normal-hearing percussionists and 39 normal-hearing nonpercussionists. Results indicate that normal-hearing percussionists have lower DPOAE amplitudes than normal-hearing nonpercussionists. DPOAE amplitudes were significantly lower at 6000 Hz in both the left and right ears for percussionists. Percussionists also more frequently had absent DPOAEs, with the greatest differences occurring at 6000 Hz (absent DPOAEs in 25% of percussionists vs 10% of nonpercussionists). When all frequencies are considered as a group, 33% of the percussionists had an absent DPOAE in either ear at some frequency, compared to only 23% of the nonpercussionists. Otoacoustic emissions are more sensitive to outer hair cell damage than pure-tone threshold measurements and can serve as an important measurement of sensory loss (i.e., outer hair cell damage) in musicians before the person perceives the hearing loss. DPOAE monitoring for musicians, along with appropriate education and intervention, might help prevent or minimize music-induced hearing loss.

Comparison of distortion product otoacoustic emissions and pure tone audiometry in occupational screening for auditory deficit due to noise exposure

2015 ◽  
Vol 129 (12) ◽  
pp. 1174-1181 ◽  
Author(s):  
N Wooles ◽  
M Mulheran ◽  
P Bray ◽  
M Brewster ◽  
A R Banerjee
Keyword(s):  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Noise Exposure ◽  
Outer Hair Cell ◽  
Cell Function ◽  
Pure Tone Audiometry ◽  
Otoacoustic Emission ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product

AbstractObjective:To examine whether distortion product otoacoustic emissions can serve as a replacement for pure tone audiometry in longitudinal screening for occupational noise exposure related auditory deficit.Methods:A retrospective review was conducted of pure tone audiometry and distortion product otoacoustic emission data obtained sequentially during mandatory screening of brickyard workers (n = 16). Individual pure tone audiometry thresholds were compared with distortion product otoacoustic emission amplitudes, and a correlation of these measurements was conducted.Results:Pure tone audiometry threshold elevation was identified in 13 out of 16 workers. When distortion product otoacoustic emission amplitudes were compared with pure tone audiometry thresholds at matched frequencies, no evidence of a robust relationship was apparent. Seven out of 16 workers had substantial distortion product otoacoustic emissions with elevated pure tone audiometry thresholds.Conclusion:No clinically relevant predictive relationship between distortion product otoacoustic emission amplitude and pure tone audiometry threshold was apparent. These results do not support the replacement of pure tone audiometry with distortion product otoacoustic emissions in screening. Distortion product otoacoustic emissions at frequencies associated with elevated pure tone audiometry thresholds are evidence of intact outer hair cell function, suggesting that sites distinct from these contribute to auditory deficit following ototrauma.

scholarly journals Evaluation of outer hair cells function of non-operated ear after mastoid drilling using distortion-product otoacoustic emissions

2019 ◽  
Vol 5 (3) ◽  
pp. 130-133
Author(s):  
Virender Singh ◽  
◽  
BS Rakesh ◽  
MB Bharathi ◽  
Kota Harish Nag ◽  
...  
Keyword(s):  
Otoacoustic Emissions ◽  
Outer Hair Cell ◽  
Cell Function ◽  
Outer Hair Cells ◽  
Distortion Product Otoacoustic Emissions ◽  
Mechanical Trauma ◽  
Suppurative Otitis Media ◽  
Distortion Product ◽  
Study Materials ◽  
And Gender

Aim: To analyze the effect of acoustic and mechanical trauma of drilling on the outer hair cell function of the non operated ear using distortion-product otoacoustic emissions (DPOAE’s) after mastoidectomy and its relation with the duration of drilling, age, and gender of the patient along with duration and permanency of the effects. Study Design: Observational study. Materials and Methods: Screening DPOAE’s were recorded preoperatively, immediate postoperative period, one hour postoperatively, 1st and 7th postoperative days in the normal ear in 94 patients who underwent tympanomastoidectomy for unilateral chronic suppurative otitis media (CSOM). DPOAE’s were measured using Neuro-audio-screener (Neurosoft Inc.) at 1.5 KHz, 2.1 KHz, 3.3 KHz, and 4.2 KHz. If DPOAE’s were absent preoperatively, the patients were not evaluated further and patients who had absent DPOAE’s post-operatively were successively followed till DPOAE’s were regained. Results: Of the 94 patients included, in 62 patients DPOAE’s were present preoperatively. Out of these 62, in 30 patients DPOAE’s were absent immediate postoperatively. On repeat testing, DPOAE’s were absent in 20 patients after 1 hour and in 8 patients after 1 day. On re-evaluation of these 8 patients after 1 week all of them had regained the DPOAE’s. In terms of duration of drilling, 66.6% patients in immediate post operative period, 90% patients in 1-hour post operative and 100 % patients on post operative day 1, having absent DPOAE’s had drilling time more than 60 minutes. Patients more than 30 years of age are affected more, but there is no preponderance for any gender. Conclusion: Nonoperated ear does have the effect of acoustic and mechanical trauma by vibration transmitted from another side during drilling of the operative ear mastoid bone. This effect is temporary and depends on the duration of drilling also.

Changes in Otoacoustic Emissions and Auditory Brain Stem Response after C/s-Platinum Exposure in Gerbils

1997 ◽  
Vol 116 (6) ◽  
pp. 585-592 ◽  
Author(s):  
Kathleen C. Y. Sie ◽  
Susan J. Norton
Keyword(s):  
Hearing Loss ◽  
Brain Stem ◽  
Otoacoustic Emissions ◽  
Outer Hair Cell ◽  
Outer Hair Cells ◽  
Distortion Product Otoacoustic Emissions ◽  
Auditory Brain Stem Response ◽  
Distortion Product ◽  
Auditory Brain Stem ◽  
Significant Difference

Ototoxicity associated with cis-platinum administration commonly presents as hearing loss and tinnitus. The hearing loss is usually an irreversible, high-frequency sensorineural loss. Histologic studies in humans and animals suggest that the outer hair cells (OHCs) are most susceptible to cis-platinum. Evoked otoacoustic emissions (EOAE), as a measure of outer hair cell function, are potentially useful in following ototoxic insults involving OHCs. Distortion-product otoacoustic emissions (DPOAE) test frequency-specific regions of the cochlea and therefore may be particularly well suited for monitoring ototoxic injuries. We measured distortion product otoacoustic emissions, at f2 = 2, 4, 6, 8, 10, and 12 kHz, in gerbils after a single large dose of cis-platinum. Animals treated with saline served as controls. The findings were compared to auditory brain stem evoked response (ABR) thresholds, using tone pips of the same frequencies. The DPOAE and ABR thresholds were measured before treatment and again 2, 5, and 14 days after drug administration. The changes in DPOAE were compared with the changes in ABR. No treatment effect was noted in the 2-day group. Animals treated with c/s-platinum demonstrated significant elevation of DPOAE and ABR thresholds compared with control animals at 5 and 14 days. There was no significant difference between the threshold changes in the 5-and 14-day groups.

Distortion Product Emissions in Normal-Hearing and Low-Frequency Hearing Loss Carriers of Genes for Waardenburg's Syndrome

1997 ◽  
Vol 106 (3) ◽  
pp. 220-225 ◽  
Author(s):  
Xue Zhong Liu ◽  
Valerie E. Newton
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Low Frequency ◽  
Normal Hearing ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Distortion Product ◽  
Initial Results

Eight patients with Waardenburg's syndrome (WS) with normal hearing and 3 additional patients exhibiting a low-frequency hearing loss were tested for the level of the acoustic distortion product 2f1-f2 by means of the Otodynamics Distortion Product Analyser (ILO92). Wide notches in distortion product otoacoustic emissions (DPOAEs) between 1,000 and 3,000 Hz were found in 7 (12 ears, 87.5%) examined patients with normal audiograms, which was a significantly higher rate than that found in the control group (10%). The 3 patients with low-frequency hearing loss gave a consistent pattern in audiometric configuration shown by both pure tone audiograms and DPOAEs. It is concluded from these initial results that DPOAEs may be a useful approach to identifying subclinical pathologic aberrations in the inner ear in WS patients, and may be a predictor of low-frequency sensorineural hearing loss.

Sign in / Sign up

Export Citation Format

Share Document