The value of serum CK-MB and myoglobin measurements for assessing perioperative myocardial infarction after cardiac surgery

1986 ◽  
Vol 46 (6) ◽  
pp. 519-526 ◽  
Author(s):  
Jean-Paul Chapelle ◽  
Magdeleine El Allaf ◽  
Robert Larbuisson ◽  
Raymond Limet ◽  
Maurice Lamy ◽  
...  
2012 ◽  
Vol 15 (1) ◽  
pp. 28-32 ◽  
Author(s):  
C. Javierre ◽  
A. Ricart ◽  
R. Manez ◽  
E. Farrero ◽  
M. L. Carrio ◽  
...  

2013 ◽  
Vol 23 (6) ◽  
pp. 29-34
Author(s):  
Andrius Macas ◽  
Giedrė Bakšytė ◽  
Laura Šilinskytė ◽  
Jūratė Petrauskaitė

Perioperative myocardial infarction (PMI) is defined as myocardial infarction (MI) during perioperative period (24-72 hours after non cardiac surgery). Worldwide, over 200 million adults have major non-cardiac surgery each year, and several million experience a major vascular complication (e.g.: nonfatal myocardial infarction). The prevalence of PMI for low risk patients without ischemic heart disease is from 0.3 to 3%, while for medium and high risk patients with coronary artery disease increases to 30%. It is believed that plaque rupture and myocardial oxygen supply-demand imbalance is the main reason of perioperative myocardial infarction. Mostly oxygen supply-demand imbalance predominates in the early postoperative period. Plaque rupture appears to be a more random event, distributed over the entire perioperative admission. Most patients with a perioperative MI do not experience ischemic symptoms, because of sedation and analgesia during surgery procedure. This is the reason why routine monitoring of troponin levels and electrocardiography in at-risk patients are needed after surgery to detect most MI. In 90% of cases troponin level inceases during the first 24 hours after surgery. Risk factors detection, serial troponin evaluation and specialised treatment can reduce hospital length of stay, treatment costs and PMI mortality.


2016 ◽  
Vol 106 (2) ◽  
pp. 180-186 ◽  
Author(s):  
A. Ollila ◽  
L. Vikatmaa ◽  
J. Virolainen ◽  
P. Vikatmaa ◽  
A. Leppäniemi ◽  
...  

Background and Aims: Perioperative myocardial infarction is an underdiagnosed complication causing morbidity, mortality, and considerable costs. However, evidence of preventive and therapeutic options is scarce. We investigated the incidence and outcome of perioperative myocardial infarction in non-cardiac surgery patients in order to define a target population for future interventional trials. Material and Methods: We conducted a prospective single-center study on non-cardiac surgery patients aged 50 years or older. High-sensitivity troponin T and electrocardiograph were obtained five times perioperatively. Perioperative myocardial infarction diagnosis required a significant troponin T release and an ischemic sign or symptom. Perioperative risk calculator was used for risk assessment. Results: Of 385 patients with systematic ischemia screening, 27 patients (7.0%) had perioperative myocardial infarction. The incidence was highest in vascular surgery—19 of 172 patients (11.0%). The 90-day mortality was 29.6% in patients with perioperative myocardial infarction and 5.6% in non–perioperative myocardial infarction patients ( p <  0.001). Perioperative risk calculator predicted perioperative myocardial infarction with an area under curve of 0.73 (95% confidence interval: 0.64–0.81). Conclusion: Perioperative myocardial infarction is a common complication associated with a 90-day mortality of 30%. The ability of the perioperative risk calculator to predict perioperative myocardial infarction was fair supporting its routine use.


1998 ◽  
Vol 12 (3) ◽  
pp. 288-294 ◽  
Author(s):  
Marie-Alexandra Alyanakian ◽  
Monique Dehoux ◽  
Didier Chatel ◽  
Christophe Seguret ◽  
Jean-Marie Desmonts ◽  
...  

2002 ◽  
Vol 39 ◽  
pp. 422
Author(s):  
Stephanie Lehrke ◽  
Evangelos Giannitsis ◽  
Margit Müller-Bardorff ◽  
Henning Steen ◽  
Armin Opitz ◽  
...  

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