Gastrointestinal Motility in Patients with the Irritable Bowel Syndrome

1987 ◽  
Vol 22 (sup130) ◽  
pp. 21-26 ◽  
Author(s):  
Hasse Abrahamsson
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gastrointestinal Motility ◽  
Irritable Bowel

scholarly journals Interstitial Cells of Cajal: A Novel Hypothesis for the Pathophysiology of Irritable Bowel Syndrome

2011 ◽  
Vol 25 (5) ◽  
pp. 277-279 ◽  
Author(s):  
Ahad Eshraghian ◽  
Hamed Eshraghian
Keyword(s):  
Irritable Bowel Syndrome ◽  
General Practitioners ◽  
Gastrointestinal Motility ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
High Prevalence ◽  
Number Of Visits ◽  
Irritable Bowel ◽  
Almost All ◽  
Cells Of Cajal

Irritable bowl syndrome (IBS) affects a large proportion of the world’s population, and accounts for a considerable number of visits to gastroenterologists and general practitioners. Despite its high prevalence, the precise mechanism of IBS has not been identified to date. The interstitial cells of Cajal (ICC) participate in the production of slow waves and the regulation of their propagation through the gastrointestinal system; thus, they are important components of gastrointestinal motility. The present review proposes that ICC play a central role in the pathophysiology of IBS. This hypothesis is based on many links between ICC and currently proposed mechanisms of IBS pathophysiology. It appears that ICC may be involved in almost all of the previously explained pathogenic mechanisms of IBS. If proven, this hypothesis may provide a key to solving the IBS mystery.

scholarly journals GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome

Cell Genomics ◽  
2021 ◽  
Vol 1 (3) ◽  
pp. 100069
Author(s):  
Ferdinando Bonfiglio ◽  
Xingrong Liu ◽  
Christopher Smillie ◽  
Anita Pandit ◽  
Alexander Kurilshikov ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gastrointestinal Motility ◽  
Stool Frequency ◽  
Irritable Bowel

scholarly journals Gastroesophageal refl ux disease and irritable bowel syndrome overlapping: unresolved issues

2021 ◽  
Vol 98 (9-10) ◽  
pp. 645-649
Author(s):  
A. A. Sheptulin ◽  
K. E. Vinogradskaya
Keyword(s):  
Irritable Bowel Syndrome ◽  
Clinical Features ◽  
Gastrointestinal Motility ◽  
Clinical Picture ◽  
Endoscopic Examination ◽  
High Rate ◽  
Esophageal Ph ◽  
The Common ◽  
The Mean ◽  
Irritable Bowel

The review presents literature data concerning the rate and clinical features in cases of the gastroesоphageal refl ux disease (GERD) and irritable bowel syndrome (IBS )overlapping. The mean rate of GERD and IBS overlapping is 36–48 .8%, but in individual articles varies from 8–11% to 71–79%. A signifi cant variation in the rate is explained by diff erent approaches to the diagnosis of GERD and IBS in various studies (use of questionnaires, endoscopic examination, esophageal pH-impedancemetry). The high rate of GERD and IBS overlapping is related to the common pathogenetic mechanisms of both diseases (disorders оf gastrointestinal motility, visceral hypersensitivity). The features of the clinical picture and treatment in cases of GERD and IBS overlapping are studied insuffi ciently and require further research.

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