scholarly journals Gastroesophageal refl ux disease and irritable bowel syndrome overlapping: unresolved issues

2021 ◽  
Vol 98 (9-10) ◽  
pp. 645-649
Author(s):  
A. A. Sheptulin ◽  
K. E. Vinogradskaya

The review presents literature data concerning the rate and clinical features in cases of the gastroesоphageal refl ux disease (GERD) and irritable bowel syndrome (IBS )overlapping. The mean rate of GERD and IBS overlapping is 36–48 .8%, but in individual articles varies from 8–11% to 71–79%. A signifi cant variation in the rate is explained by diff erent approaches to the diagnosis of GERD and IBS in various studies (use of questionnaires, endoscopic examination, esophageal pH-impedancemetry). The high rate of GERD and IBS overlapping is related to the common pathogenetic mechanisms of both diseases (disorders оf gastrointestinal motility, visceral hypersensitivity). The features of the clinical picture and treatment in cases of GERD and IBS overlapping are studied insuffi ciently and require further research.

2012 ◽  
Vol 17 (3) ◽  
pp. 56-59
Author(s):  
M. S. Grigorovich

The significance of the problem of acute intestinal infections (AII) to date is associated with both their prevalence and high rate of adverse effects in the outcome of the disease. In modern literature there is enough information about the frequent occurrence in AII patients microbiota disorders, immune system imbalances, identifying signs of reactive changes ofpancreatic tissue and functional disorders of biliary tract, lactase deficiency, long-term disorders of functional activity of the digestive system. The data about AII as one of the factors of forming the gastrointestinal tract pathology, including irritable bowel syndrome have been accumulated.


Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4513
Author(s):  
Elodie Schneider ◽  
Jean-Marc Sabaté ◽  
Michel Bouchoucha ◽  
Serge Hercberg ◽  
Mathilde Touvier ◽  
...  

(1) Background: Specific foods, and more particularly, fermentable oligo-, di-, and mono-saccharides and polyols (FODMAPs) are often considered as triggers of digestive symptoms in Irritable Bowel Syndrome (IBS). Our aim was to study FODMAP consumption in controls and IBS participants in a large French population-based cohort; (2) Methods: Participants from the NutriNet-Santé cohort study completed the Rome IV and IBS-SSS questionnaire in a cross sectional study. Among them, 27,949 eligible participants had previously completed three 24-h recalls as well as anthropometrics, socio-demographical and lifestyle data. Total FODMAP intake (in g/day) was computed using a specific composition table. The association between FODMAPs and IBS was estimated through multivariable logistic regression models; (3) Results: Included participants were mainly women (75.4%) and the mean age was 43.4 ± 14.1 years. FODMAPs accounted for a mean daily intake of 19.4 ± 9.5 g/day. Overall 1295 participants (4.6%) were identified with an IBS. After adjusting for confounding factors, IBS participants had lower intakes in FODMAPs than non-IBS ones (aOR: 0.88, 95% CI: 0.82–0.95, p-value: 0.001). IBS severity was associated with more frequent low FODMAP intakes (<9 g/day); (4) Conclusions: Participants tended to consume 19 g of FODMAPs per day, but slightly less for IBS participants than for controls. In IBS participants, higher severity was associated with lower intakes.


2021 ◽  
Vol 51 (3) ◽  
Author(s):  
Luis Soifer ◽  
José Tawil ◽  
Alejandro Rey ◽  
Laura Solé ◽  
Silvia Bernstein

Introduction. Irritable bowel syndrome (IBS) accounts for a significant deterioration in the quality of life of patients who suffer from it and is a common reason for consultation in gastroenterology. The treatment of this syndrome includes a wide variety of medications and recommendations based on different factors of its physiopathology. However, the results are usually variable and sometimes unsatisfactory for either the patient or the treating physician. The main objective of the present work is to describe the different treatments used by gastroenterologists in the management of IBS in Argentina. Materials and methods. Questionnaire of forty-seven questions, prepared by experts, distributed by medical associations of gastroenterology in Argentina and answered by specialists via Google Forms. Results. 304 responses, 157 from women (51.6%) and 147 from men (48.4%). The mean age was 44 and 49.9 years, respectively. 87.5% consider improvement of quality of life as the main goal of treatment. Regarding physiopathology of diarrhea variant irritable bowel syndrome (IBS-D), 49.5% considered emotional stress, while for constipation variant irritable bowel syndrome (IBS-C), 42.8% considered it multifactorial, with a predominance of slow colonic transit. No treatment option was rated as very effective by more than 50% of the respondents. Rifaximin was considered the most effective treatment in IBS-D, while polyethylene glycol was for IBS-C. Statistical significant differences were observed among gastroenterology subspecialties in the treatment of IBS-D with respect to the efficacy of diet, amitriptyline and antibiotics other than rifaximin, and regarding the effectiveness for bisacodyl/picosulfate and antibiotics in the treatment of IBS-C. Conclusion. The most common pathophysiological mechanismin IBS-D is stress. The vast majority of respondents consider that the main goal of treatment is the improvement of the quality of life, over symptomatic relief. None of the drugs is considered very effective in the treatment of the different IBS variants by at least 50% of those surveyed. Statistically significant differences were observed in the proportion of monthly consultations for IBS regarding to age and in the effectiveness considered for some treatments in relation to the subspecialty of physicians. The therapeutic approach to IBS by Argentine gastroenterologists is varied and somewhat heterogeneous, resulting in a still inappropriate management of this condition.


2018 ◽  
Vol 25 (02) ◽  
pp. 173-179
Author(s):  
Syeda Rabia ◽  
Naeem Akhtar Qureshi ◽  
Afsha Shahid ◽  
Hira Afreen

Objectives: To determine the frequency and associated risk factors of chronicpelvic pain (CPP) in educated women under 30 years of age. Study Design: A cross sectionalstudy. Setting: North Naziabad and Gulshan e Iqbal towns of Karachi. Period: January to July2017. Method: Data was collected through convenient sampling. Informed verbal consentwas taken before data collection. A questioner was used to collect demographic and obstetricdata. Screening of Anxiety and depression was done using standard tool Hospital basedanxiety and depression scale (HADS).Result were analyzed on SPSS. Result: The mean ageof women were 25 years, SD = 4.31. The frequency of chronic pelvic pain was 29% (116).Gynecological cause was found in 68.9% (80). Irritable bowel syndrome was seen in 9% (36)women. Significant association of CPP was noted with Dysmenorrhoea (p-value=000,OR=.207), Dyspareunia (p-value = .000, OR = .166), Heavy menstrual flow (p-value = .033, OR= .333), married (p-value = .000, OR = .414), Vaginal discharge (p-value = .000, OR = .260),Anxiety (p-value = .000, OR = .300), depression (p-value = .002, OR = .452), Normal mentalstatus (p-value = .000, OR = 2.488), Irritable bowel syndrome (p-value = .000, OR = .169)and PMS (p-value = .000, OR = .438). Conclusion: Frequency of chronic pelvic pain is high inyoung educated women. Gynecological causes, irritable bowel syndrome and psychologicaldisorder are significantly associated with CPP. 


2019 ◽  
Vol 64 (7) ◽  
pp. 1923-1928 ◽  
Author(s):  
Lilani P. Perera ◽  
Mark Radigan ◽  
Corinne Guilday ◽  
Indrani Banerjee ◽  
Daniel Eastwood ◽  
...  

Author(s):  
Mallikarjun . ◽  
Channabasavanna B. M.

Grahani Roga described in classical text books of Ayurveda represents a group of disorders of digestive system caused by impairment of Agni. Grahani is such a disorder, where in its significance is emphasized by its inclusion among Ashtamaha Gadas. The cardinal features of Grahani explained in the clasical text books of Ayurveda, have at most similarities with the clinical features of Irritable Bowel Syndrome (IBS) explained in western medicine. A total of 15 patients were selected and treated with Erandamooladi Niruha Basti and Changeryadi Ghrita Anuvasana Basti, was given in Yoga Basti pattern according to inclusive and exclusive criteria. Special case proforma was designed and parameters were assessed. It showed highly significant results in all the parameters at the level of p less than 0.01.


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