Chronic Cannulation and Fistulization Procedures in Swine: A Review and Recommendations

1998 ◽  
Vol 11 (1) ◽  
pp. 7-20 ◽  
Author(s):  
M. M. Swindle ◽  
A. C. Smith ◽  
J. A. Goodrich
Keyword(s):  
Chronic Cannulation

Chronic arterial and venous access in the unrestrained rat

1980 ◽  
Vol 238 (4) ◽  
pp. H599-H603 ◽  
Author(s):  
M. E. Burt ◽  
J. Arbeit ◽  
M. F. Brennan
Keyword(s):  
Stainless Steel ◽  
Thoracic Aorta ◽  
Superior Vena Cava ◽  
Postoperative Period ◽  
Superior Vena ◽  
Vena Cava ◽  
Venous Access ◽  
Coiled Spring ◽  
Chronic Infusion ◽  
Chronic Cannulation

A system is described for chronic cannulation of the thoracic aorta and superior vena cava in the rat. This system employs a protective stainless steel coiled spring and water tight swivel and allows chronic infusion of solutions and simultaneous intermittent blood sampling for prolonged periods of time in the undisturbed unanesthetized rat. The rats (200-250 g) lost approximately 25 g in the immediate postoperative period, but then gained weight at a relatively normal rate (cannulated rats, 2.23 g/day; control rats, 2.29 g/day).

A simple method for chronic cannulation of the portal vein in intact unrestrained rats

1988 ◽  
Vol 255 (2) ◽  
pp. G191-G193 ◽  
Author(s):  
A. Braillon ◽  
M. J. Brody
Keyword(s):  
Portal Vein ◽  
Direct Injection ◽  
New Method ◽  
Hypertensive Rats ◽  
Portal Vein Pressure ◽  
Simple Method ◽  
Blood Samples ◽  
Mesenteric Vein ◽  
Disease States ◽  
Chronic Cannulation

A simple new method is described for chronic cannulation of the portal vein in rats. A Silastic catheter (0.64 mm OD) with an internal metallic leader is directly inserted in the junction of the two small ileal veins. The catheter is advanced into the mesenteric vein to the portal vein. Then the leader is removed and the catheter tunneled out the back of the neck. This method allows for the measurement of portal vein pressure, direct injection of substances in the portal vein, or blood samples for at least 1 wk in intact unrestrained rats. Validation included the presence of elevated portal vein pressure in portal hypertensive rats compared with normal rats and the absence of clot development in the portal vein. This method should help provide a better understanding of hepatic physiology and pharmacology in normal and disease states.

A method to study pulmonary vascular response in the conscious newborn piglet

1987 ◽  
Vol 65 (5) ◽  
pp. 785-790 ◽  
Author(s):  
J. Y. Coe ◽  
P. M. Olley ◽  
F. Hamilton ◽  
T. Vanhelder ◽  
F. Coceani
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Veins ◽  
Newborn Piglet ◽  
Systemic Resistance ◽  
New Methods ◽  
Left And Right ◽  
The Right ◽  
Neck Vessels ◽  
Chronic Cannulation ◽  
Right Atria

New methods for chronic instrumentation of the newborn piglet are described, which allow continuous monitoring of not only pressures in the pulmonary artery and aorta but also in the left and right atria, pulmonary vein, as well as main branch pulmonary artery flows. Changes in pulmonary vascular tone to short-acting vasoactive agents can be recognized by redistribution of flow between lungs and localized to the precapillary vessels or pulmonary veins. Furthermore, vasoactive response in small pulmonary veins may be investigated as well as selective metabolic studies across the right lung. Methods are also described for the chronic cannulation of the neck vessels permitting repeated introduction of catheters on separate study days in the conscious piglet. The pulmonary circulation of the piglet constricts briskly to moderate hypoxemia ([Formula: see text], 1 Torr = 133.32 Pa) with little change in cardiac output or systemic resistance. The piglet demonstrated responses to dilator and constrictor prostaglandins generally similar to the lambs and other species. None of these agents significantly affect pulmonary venous tone.

scholarly journals CHRONIC CANNULATION OF THE INTRADURAL OR EXTRADURAL SPACE IN THE RAT

1984 ◽  
Vol 56 (4) ◽  
pp. 405-410 ◽  
Author(s):  
M. BAHAR ◽  
M. ROSEN ◽  
M.D. VICKERS
Keyword(s):  
Chronic Cannulation ◽  
Extradural Space

Chronic cannulation for intermittent intravenous fluid administration

1975 ◽  
Vol 38 (4) ◽  
pp. 750-751
Author(s):  
R. A. Mostardi ◽  
D. Worsencroft ◽  
J. Stern ◽  
F. Vanessen
Keyword(s):  
Fluid Administration ◽  
Intravenous Fluid ◽  
Venous Cannulation ◽  
Weekly Administration ◽  
Term Administration ◽  
Intravenous Fluid Administration ◽  
Chronic Cannulation ◽  
Type Apparatus

A system is described for rapid and effective venous cannulation for long-term administration of fluids in rabbits. This method is completely free of any harness or sling-type apparatus and in no way interferes with the normal mobility of the animal. The animals maintained in this way have participated in programs of tri-weekly administration (2–3 ml/dose) of fluid for as long as 5 mo.

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