Histological chorioamnionitis – implication for bacterial colonization, laboratory markers of infection, and early onset sepsis in very-low-birth-weight neonates

2011 ◽  
Vol 25 (4) ◽  
pp. 364-368 ◽  
Author(s):  
Shing Yan Robert Lee ◽  
Chi Wai Leung
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Bacterial Colonization ◽  
Laboratory Markers ◽  
Early Onset Sepsis

Changes in Pathogens Causing Early-Onset Sepsis in Very-Low-Birth-Weight Infants

2002 ◽  
Vol 347 (4) ◽  
pp. 240-247 ◽  
Author(s):  
Barbara J. Stoll ◽  
Nellie Hansen ◽  
Avroy A. Fanaroff ◽  
Linda L. Wright ◽  
Waldemar A. Carlo ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Early Onset Sepsis

scholarly journals Clinical profile and outcome of early onset sepsis in high risk very low birth weight neonates

2018 ◽  
Vol 5 (2) ◽  
pp. 389 ◽  
Author(s):  
Omprakash S. Shukla ◽  
Aditi Rawat
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Blood Culture ◽  
Low Birth Weight ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Gram Negative ◽  
Early Onset Sepsis ◽  
Culture Positive

Background: Neonatal sepsis is one of the main causes of mortality and morbidity, especially in very low birth weight neonates (birth weight <1499 grams) despite the progress in hygiene, introduction of new and potent antimicrobial agents for treatment and advanced measures for diagnosis. The aim of the study was to find correlation of clinical features and risk factors of neonatal sepsis in culture positive cases.Methods: A cross- sectional study was carried out in one hundred neonates with risk factors of septicemia after obtaining informed consent. Blood culture was done using Bactec Peds Plus/F Culture as a gold standard to diagnose septicaemia. Correlation of  risk factors, clinical features with laboratory findings was obtained by using chi-square test. p-value of less than 0.05 was considered as significant.Results: Out of 100 neonates with suspected sepsis, BACTEC culture proven sepsis was seen in 40% cases. Gram negative sepsis was seen in 62.5% cases. The most common bacteria for early onset sepsis were Klebsiella, Pseudomonas and MRSA contributing 17% each to the bacteriological profile. The most common predisposing factor and clinical feature in culture positive cases were Premature rupture of membrane >24 hours (67%) and bleeding/petechia/pupura (72%) respectively. The major cause of mortality was pulmonary hemorrhage.Conclusions: Gram negative organism were more common and associated with higher mortality. Blood culture positivity increases with increase in number of risk factors in neonatal septicemia. A detailed history and thorough clinical examination is vital for early recognition of sepsis. 

Diagnostic accuracy and prognostic value of the CD64 index in very low birth weight neonates as a marker of early-onset sepsis

2014 ◽  
Vol 46 (6) ◽  
pp. 433-439 ◽  
Author(s):  
Mario Motta ◽  
Alice Zini ◽  
Antonio Regazzoli ◽  
Elena Garzoli ◽  
Gaetano Chirico ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Diagnostic Accuracy ◽  
Early Onset ◽  
Prognostic Value ◽  
Very Low Birth Weight ◽  
Early Onset Sepsis

Changes in Pathogens Causing Early-Onset Sepsis in Very-Low-Birth- Weight Infants

2003 ◽  
Vol 58 (1) ◽  
pp. 17-18
Author(s):  
Barbara J. Stoll ◽  
Nellie Hansen ◽  
Avroy A. Fanaroff ◽  
Linda L. Wright ◽  
Waldemar A. Carlo ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Early Onset Sepsis

Early onset sepsis in very low birth weight newborn infants

2012 ◽  
Vol 25 (sup3) ◽  
pp. 21-25 ◽  
Author(s):  
Valentina Pisani ◽  
Bianca Bizzarri ◽  
Veronica Cardi ◽  
Roberto Pedicino ◽  
Fabio Natale ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Newborn Infants ◽  
Early Onset Sepsis

Outcome of Early-Onset Sepsis in a National Cohort of Very Low Birth Weight Infants

PEDIATRICS ◽  
2010 ◽  
Vol 125 (4) ◽  
pp. e736-e740 ◽  
Author(s):  
G. Klinger ◽  
I. Levy ◽  
L. Sirota ◽  
V. Boyko ◽  
L. Lerner-Geva ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Early Onset ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Early Onset Sepsis ◽  
National Cohort
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