TTC5 expression associates with survival in triple negative breast cancer.

Triple Negative ◽

Tetratricopeptide Repeat ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Repeat Domain ◽

Significant Gene ◽

Tetratricopeptide Repeat Domain

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of tetratricopeptide repeat domain 5, encoded by TTC5 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, TTC5 expression was correlated with recurrence-free survival in patients with breast cancer. TTC5 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

DNAJC28 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/v45h2 ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Gene Expression ◽

Overall Survival ◽

Cancer Patients ◽

Microarray Data ◽

Triple Negative ◽

Breast Cancer Patients ◽

Primary Tumors ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of DnaJ (Hsp40) homolog, subfamily C, member 28, encoded by DNAJC28 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, DNAJC28 expression was correlated with overall survival in patients with breast cancer. DNAJC28 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

VPS52 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/tjzdh ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Free Survival ◽

Significant Gene ◽

Vacuolar Protein

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of vacuolar protein sorting 52, encoded by VPS52 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, VPS52 expression was correlated with recurrence-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. VPS52 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

MAP4K2 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/rx3jv ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Triple Negative ◽

Molecular Subtype ◽

Mitogen Activated Protein Kinase ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Mitogen Activated Protein ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of mitogen-activated protein kinase kinase kinase kinase 2, encoded by MAP4K2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, MAP4K2 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. MAP4K2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

PAX5 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/rh6xb ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Gene Expression ◽

Cancer Patients ◽

Microarray Data ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of paired box 5, encoded by PAX5 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, PAX5 expression was significantly correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. PAX5 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

BACH2 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/7e52n ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Microarray Data ◽

Leucine Zipper ◽

Triple Negative ◽

Breast Cancer Patients ◽

Basic Leucine Zipper ◽

Primary Tumors ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of BTB and CNC homology 1, basic leucine zipper transcription factor 2, encoded by BACH2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, BACH2 expression was correlated with overall survival in patients with breast cancer. BACH2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

GBP5 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/dqx69 ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Significant Gene ◽

Inflammasome Component ◽

Guanylate Binding Protein

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival at time of analysis: dead or alive. The inflammasome component and guanylate-binding protein GBP5 emerged as among the most significant differences, transcriptome-wide, when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, GBP5 expression was significantly correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. GBP5 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

PD-L2 (PDCD1LG2) expression associates with survival in triple negative breast cancer.

10.31219/osf.io/svq6u ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Microarray Data ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Programmed Cell Death 1 ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of programmed cell death 1 ligand 2, encoded by PDCD1LG2, also known as PD-L2, when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, PD-L2 expression was significantly correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. PD-L2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

HES1 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/zy5ha ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

Hes1 Expression ◽

Significant Gene ◽

Enhancer Of Split

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of hairy and enhancer of split 1, encoded by HES1 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, HES1 expression was significantly correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. HES1 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

TAGAP expression associates with survival in triple negative breast cancer.

10.31219/osf.io/f6pz5 ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

T Cell Activation ◽

Cell Activation ◽

Triple Negative ◽

Molecular Subtype ◽

Breast Cancer Patients ◽

Primary Tumors ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of T-cell activation RhoGTPase activating protein, encoded by TAGAP when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, TAGAP expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. TAGAP may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.

STAT4 expression associates with survival in triple negative breast cancer.

10.31219/osf.io/r5vyj ◽

2021 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Microarray Data ◽

Triple Negative ◽

Molecular Subtype ◽

Signal Transducer ◽

Breast Cancer Patients ◽

Primary Tumors ◽

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival at time of analysis: dead or alive. We observed significant transcriptome-wide differential expression of signal transducer and activator of transcription 4, encoded by STAT4 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, STAT4 expression was significantly correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. STAT4 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.