scholarly journals Further Investigation of the Negative Association between Hypertension and Peripheral Neuropathy in the Elderly: An Oklahoma Physicians Resource/Research Network (OKPRN) Study

2006 ◽  
Vol 19 (3) ◽  
pp. 240-250 ◽  
Author(s):  
D. Y. Cho ◽  
J. W. Mold ◽  
M. Roberts
Author(s):  
Nishant Kumar Singh ◽  
Hirni J. Patel ◽  
Mohit Buddhadev ◽  
S P Srinivas Nayak ◽  
Gunosindhu Chakraborthy

Peripheral nerves are susceptible to damage by a wide array of toxins, medications, and vitamin deficiencies. Vitamin B12 (VB12) deficiency neuropathy is a rare debilitating disease that affects mostly the elderly. It is important to consider these etiologies when approaching patients with a variety of neuropathic presentations in this review were have included most relevant and latest information on mechanisms causing Peripheral neuropathy in VB12 deficiency. We also have included cardiovascular disorders and their management. Hyperhomocysteinemia has been implicated in endothelial dysfunction and cardiovascular disease. The association of homocysteine (Hcy) and VB12 with cardiovascular risk factors in patients with coronary artery disease (CAD) has also been studied Keywords: Peripheral Neuropathy, Vitamin B12 Deficiency, Cardiovascular Disease and Homocysteine.


2019 ◽  
Vol 90 (3) ◽  
pp. e44.3-e45
Author(s):  
S Hall ◽  
M Myers ◽  
A Sadek ◽  
M Baxter ◽  
C Dare ◽  
...  

ObjectivesFalls from standing are an important cause of vertebral fractures, particularly in the elderly. They are associated with significant morbidity and long-term mortality. The aim of this study was to determine the treatment and outcomes, in a single centre, of managing spinal fractures due to falls from standing height.DesignRetrospective case note review of patients with a fracture sustained due to a fall from standing (2011–2016 inclusive).Subjects229 patients with average age 76.6±14.5 years; 134 (58.5%) female.MethodsPatients were identified from the Trauma Audit and Research Network database. Case notes were reviewed for demographics, treatment details and outcome at 6 months post-admission.Results1408 patients were admitted with spinal fractures of which 229 (16.3%) sustained a fall from standing height. Two hundred and eighty-three fractures were identified in the 229 patients, which were distributed in the cervical (n=140), thoracic (n=65) and lumbar (n=78) spine. The average ISS score was 9.7±5.4. Twenty-three (10.0%) patients had either incomplete or complete spinal cord injury. Fifty-six (24.5%) patients underwent surgical intervention. Forty-three patients (18.7%) died within 6 months and increasing age and Charlson co-morbidity score were associated with higher mortality.ConclusionsFalls from standing comprise a large portion of the spinal service emergency workload. They are associated with a high 6 month mortality similar to other fragility fractures experienced by the elderly.


2013 ◽  
Vol 3 (5) ◽  
pp. 421-430 ◽  
Author(s):  
B. C. Callaghan ◽  
J. F. Burke ◽  
A. Rodgers ◽  
R. McCammon ◽  
K. M. Langa ◽  
...  

2020 ◽  
Author(s):  
Anthony Marcelo Chicaiza ◽  
Katherine Lopez ◽  
Kenneth W. Lin ◽  
Ranit Mishori ◽  
Dongyu Zhang ◽  
...  

Abstract Background For women age 75 and older, there is insufficient evidence to recommend routine breast cancer screening, as the benefits may not outweigh harms. The objective of this study was to identify variables that clinicians consider influential when making screening mammography recommendations for these women and to assess the acceptability and feasibility of a patient print intervention designed to support patient decision-making and patient-clinician communication about stopping mammography. Methods Primary care clinicians who were part of a practice-based research network and patients aged 74–85 from this network completed surveys online and by phone, respectively. Results Twenty-two clinicians (18% response rate) completed the survey. The mean age at which clinicians reported that they would stop recommending screening mammography was 77.14 years. Clinicians were most likely to cite patient comorbidity [86.4%], functional status [77.3%], and cancer family history [63.6%], as well as U.S. Preventive Services Task Force (USPSTF) guidelines [81.8%] and new research regarding screening mammography [77.3%] as factors influencing their recommendations. Fourteen patients (70% enrollment rate) completed baseline surveys and received personalized booklets. Eleven (79% retention) completed follow-up surveys, reporting high intervention acceptability. Decreases in perceived breast cancer risk were significant for lifetime perceived risk (M = 26.91 vs. 4.18, p = < 0.01). Cancer worry decreased slightly (M = 1.27 vs. 1.09, p = 0.77). Conclusions An intervention that addresses a patients’ cancer risk and comorbidities that aligns with USPSTF guidelines appears feasible and acceptable to patients and aligns with clinicians’ values.


2005 ◽  
Vol 40 (6) ◽  
pp. 478-482
Author(s):  
Joel Shuster

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), to discuss methods of prevention, and to promote reporting of ADRs to the FDA's medwatch program (800-FDA-1088). If you have reported an interesting preventable ADR to medwatch, please consider sharing the account with our readers.


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