Brief online cognitive behavioural intervention for dysfunctional worry related to the covid-19 pandemic: Pre-specified interim results from a randomised trial

2020 ◽  
Author(s):  
Tove Wahlund ◽  
David Mataix-Cols ◽  
Klara Lauri ◽  
Elles de Schipper ◽  
Brjánn Ljótsson ◽  
...  

Objective: To investigate if a brief self-guided, online cognitive behavioural intervention can reduce the degree of dysfunctional worry related to the covid-19 pandemic.Design: Randomised waiting list controlled trial.Setting: Swedish general population. Participants: Self-referred adults reporting daily uncontrollable worry about covid-19 and its possible consequences. The trial aims to include 670 participants in total. Here we present the results of a pre-specified interim analysis on data from the first 300 randomised participants. Intervention: A brief (3-week) self-guided, online cognitive behavioural intervention targeting dysfunctional worry related to the covid-19 pandemic. Main outcome measure: A covid-19 adapted version of the self-rated Generalised Anxiety Disorder 7-item scale assessed at baseline, week 1, week 2 and week 3 (primary endpoint). Results: The main pre-specified intention-to-treat analysis indicated significant reductions in covid-19-related worry for the intervention compared to waiting list (=2.64, Z=4.02, p<.001), corresponding to a medium effect size (bootstrapped d=0.69 [95% CI; 0.43 to 0.95]). Improvements were also seen on several secondary measures, including mood, daily functioning and intolerance of uncertainty. Participant satisfaction was high. No serious adverse events were recorded.Conclusions: A brief digital and easily scalable self-guided psychological intervention can significantly reduce dysfunctional worry and associated behavioural symptoms related to the covid-19 pandemic. The full trial will provide more precise estimates of the magnitude of the effects, their long-term durability, and potential adverse effects. Trial registration: ClinicalTrials.gov registration ID: NCT04341922, registered on April 10 2020 before inclusion of the first participant.

2020 ◽  
pp. 1-9
Author(s):  
Tove Wahlund ◽  
David Mataix-Cols ◽  
Klara Olofsdotter Lauri ◽  
Elles de Schipper ◽  
Brjánn Ljótsson ◽  
...  

<b><i>Introduction:</i></b> Worries about the immediate and long-term consequences of the COVID-19 pandemic may for some individuals develop into pervasive worry that is disproportionate in its intensity or duration and significantly interferes with everyday life. <b><i>Objective:</i></b> The aim of this study was to investigate if a brief self-guided, online psychological intervention can reduce the degree of dysfunctional worry related to the COVID-19 pandemic and associated symptoms. <b><i>Methods:</i></b> 670 adults from the Swedish general population reporting daily uncontrollable worry about CO­VID-19 and its possible consequences (e.g., illness, death, the economy, one’s family) were randomised (1:1 ratio) to a 3-week self-guided, online cognitive behavioural intervention targeting dysfunctional COVID-19 worry and associated symptoms, or a waiting list of equal duration. The primary outcome measure was a COVID-19 adapted version of the Generalised Anxiety Disorder 7-item scale administered at baseline and weeks 1–3 (primary endpoint). Follow-up assessments were conducted 1 month after treatment completion. The trial was registered on ClinicalTrials.gov (NCT04341922) before inclusion of the first participant. <b><i>Results:</i></b> The main pre-specified intention-to-treat analysis indicated significant reductions in COVID-19-related worry for the intervention group compared to the waiting list (β = 1.14, <i>Z</i> = 9.27, <i>p</i> &#x3c; 0.001), corresponding to a medium effect size (bootstrapped <i>d</i> = 0.74 [95% CI: 0.58–0.90]). Improvements were also seen on all secondary measures, including mood, daily functioning, insomnia, and intolerance of uncertainty. Participant satisfaction was high. No serious adverse events were recorded. <b><i>Conclusions:</i></b> A brief digital and easily scalable self-guided psychological intervention can significantly reduce dysfunctional worry and associated behavioural symptoms related to the COVID-19 pandemic.


2020 ◽  
Author(s):  
Tove Wahlund ◽  
David Mataix-Cols ◽  
Klara Lauri ◽  
Elles de Schipper ◽  
Brjánn Ljótsson ◽  
...  

Introduction: Worries about the immediate and long-term consequences of the COVID-19 pandemic may for some individuals develop into pervasive worry that is disproportionate in its intensity or duration and significantly interferes with everyday life. Objective: The aim of this study was to investigate if a brief self-guided, online psychological intervention can reduce the degree of dysfunctional worry related to the COVID-19 pandemic and associated symptoms.Methods: 670 adults from the general Swedish general population reporting daily uncontrollable worry about COVID-19 and its possible consequences (e.g. illness, death, the economy, one’s family) were randomised (1:1 ratio) to a 3-week self-guided, online cognitive behavioural intervention targeting dysfunctional COVID-19 worry and associated symptoms, or a waiting list of equal duration. The primary outcome measure was a COVID-19 adapted version of the Generalised Anxiety Disorder 7-item scale assessed at baseline and weeks 1-3 (primary endpoint). Follow-up assessments were conducted one month after treatment completion. The trial was registered on ClinicalTrials.gov (NCT04341922) before inclusion of the first participant.Results: The main pre-specified intention-to-treat analysis indicated significant reductions in COVID-19-related worry for the intervention group compared to waiting list (=1.14, Z=9.27, p&lt;.001), corresponding to a medium effect size (bootstrapped d=0.74 [95% CI; 0.58 to 0.90]). Improvements were also seen on all secondary measures, including mood, daily functioning, insomnia and intolerance of uncertainty. Participant satisfaction was high. No serious adverse events were recorded.Conclusions: A brief digital and easily scalable self-guided psychological intervention can significantly reduce dysfunctional worry and associated behavioural symptoms related to the COVID-19 pandemic.


2015 ◽  
pp. 34-39
Author(s):  
Bidita Bhattacharya

Avoidant personality disorder is characterized by pervasive behavioural, emotional and cognitive avoidances. There are evidences that both psychodynamic therapy and cognitive behavior therapy are effective treatments of personality disorders. In the current case study a 21 year old male with a diagnosis of avoidant personality disorder was taken for psychological intervention through cognitive behavioural approach. Total 33 sessions were held over a period of four months. The client reported significant improvement in therapy. His functioning level and social skills were improved and was looking forward to address his problems in more optimistic approach.


1998 ◽  
Vol 26 (4) ◽  
pp. 345-357 ◽  
Author(s):  
Ruth Pat-Horenczyk

This study was designed to investigate the effects of a short-term cognitive-behavioural intervention, as part of a comprehensive medical project of withdrawal from hypnotics, on attitudes toward insomnia. Twenty-four subjects volunteered to participate in a withdrawal project conducted in a sleep clinic for five weeks. All subjects were chronic users of a long-acting hypnotic, and free from other psychotropic drugs. Along with the gradual decrease in hypnotics’ dosage, the programme consisted of sleep evaluations by polysomnography, actigraphic monitoring, daily sleep diaries, and periodical medical examinations. Upon termination of the withdrawal stage, all subjects received a short-term cognitive-behavioural treatment consisting of six sessions and directed at attitude change and correction of misconceptions about sleep and insomnia, and on promoting psychological strategies for coping with the sleep disturbances. Attitudes toward insomnia were measured by the DBAS – Dysfunctional Beliefs and Attitudes about Sleep Scale, administered at three points of time: on the first day of the programme (Time 1), at the termination of the medical withdrawal stage (Time 2), and a week after completion of the short-term cognitive behavioural treatment (Time 3). A multivariate analysis showed a significant effect of the time of measurement on all five subscales of the DBAS. Subsequent analyses indicated that the major change in attitudes was specific to the direct cognitive-behavioural intervention and occurred between Time 2 and Time 3. In follow-ups conducted at 3 and 12 months after completion of the withdrawal project, the majority of the participants (72%) reported refrain from hypnotic use, and regarded the psychological intervention as the major cause of their successful withdrawal from sleeping pills.


2012 ◽  
Vol 106 (6) ◽  
pp. 802-810 ◽  
Author(s):  
Glenys D. Parry ◽  
Cindy L. Cooper ◽  
Julia M. Moore ◽  
Ghasem Yadegarfar ◽  
Mike J. Campbell ◽  
...  

1993 ◽  
Vol 23 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Sean Germond ◽  
Hein Helgo Schomer ◽  
Orlando Llewellyn Meyers ◽  
Lindsay Weight

Psychological adjustment is thought to play an important role in determining pain experience, disease status, and immune function in rheumatoid arthritis (RA). Fourteen female RA out-patients were tested longitudinally in a matched-random assigned two-groups design with cognitive-behavioural intervention designed to improve pain and stress management skills. Pre-intervention correlational analyses tested the extent to which mood disturbance, self-perceptions of coping efficacy, health locus of control, and stressful life experience were related to pain, disease activity, functional status and lymphocyte proliferation rate variables. Intra- and inter-group analyses were conducted to determine treatment effects, and case studies were conducted. RA was characterized more by poor psychological health status than physical disability, with pain more a function of psychological adjustment than actual disease status. No significant treatment effects were observed. Case studies indicated the complex nature of the individual disease experience. The value of cognitive-behavioural intervention in RA, and implications for future-related research are discussed in terms of such findings.


2008 ◽  
Vol 193 (6) ◽  
pp. 493-500 ◽  
Author(s):  
U. Schmidt ◽  
M. Andiappan ◽  
M. Grover ◽  
S. Robinson ◽  
S. Perkins ◽  
...  

BackgroundCognitive–behavioural self-care is advocated as a first step in the treatment of bulimia nervosa.AimsTo examine the effectiveness of a CD–ROM-based cognitive–behavioural intervention in bulimia nervosa and eating disorder not otherwise specified (NOS) (bulimic type) in a routine setting.MethodNinety-seven people with bulimia nervosa or eating disorder NOS were randomised to either CD–ROM without support for 3 months followed by a flexible number of therapist sessions or to a 3-month waiting list followed by 15 sessions of therapist cognitive–behavioural therapy (CBT) (ISRCTN51564819). Clinical symptoms were assessed at pre-treatment 3 months and 7 months.ResultsOnly two-thirds of participants started treatment. Although there were significant group × time interactions for bingeing and vomiting, favouring the CD–ROM group at 3 months and the waiting-list group at 7 months, post hoc group comparisons at 3 and 7 months found no significant differences for bingeing or vomiting. CD–ROM-based delivery of this intervention, without support from a clinician, may not be the best way of exploiting its benefits.


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