scholarly journals Acute acalculous cholecystitis and gall bladder perforation induced by Salmonella enterica serovar typhi

1970 ◽  
Vol 31 (3) ◽  
pp. 63-65
Author(s):  
N. S. Khatri ◽  
S. Koirala ◽  
A. Arjyal ◽  
P. Maskey ◽  
S. Poudel ◽  
...  

Salmonella Typhi is a causative agent of enteric fever, which is an ongoing public health problem in urban areas of the Kathmandu valley in Nepal. It is estimated that approximately 5 % of people in an endemic enteric fever area may asymptomatically carry Salmonella Typhi in the gall bladder. Here we describe a rare clinical manifestation of chronic Salmonella carriage. A 40 year old male resident of Kathmandu underwent an emergency cholecystectomy for acute cholecystitis and gall bladder perforation. No stone was identified but Salmonella Typhi was cultured from the gall bladder. Key Words: Acalculous cholecystitis, perforation, Salmonella Typhi. DOI: 10.3126/joim.v31i3.3002 Journal of Institute of Medicine, December, 2009; 31(3)63-65


2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Vimaleswaran Koculen ◽  
Umesh Jayarajah ◽  
Anil P. Ambawatte

Gall bladder perforation is a rare but serious complication of acute cholecystitis. Gall bladder perforations commonly occur in patients with comorbidities and in association with gall stones. We report a rare occurrence of intrahepatic type II perforation of the gall bladder in a previously healthy elderly male with acalculous cholecystitis. Lack of early positive findings related to clinical assessment, laboratory workup, and imaging resulted in a challenging diagnosis. High degree of clinical suspicion and close monitoring in such patients is necessary to detect early deterioration and improve outcomes.



2015 ◽  
Vol 33 (2) ◽  
pp. 41
Author(s):  
Vijay Agarwal ◽  
Dhanesh Kumar ◽  
Ajay Kumar ◽  
Atul Jain


2010 ◽  
Vol 31 (3) ◽  
Author(s):  
N. S. Khatri ◽  
S. Koirala ◽  
A. Arjyal ◽  
P. Maskey ◽  
S. Poudel ◽  
...  


Author(s):  
Maymona Choudry ◽  

Typhoid fever is one of the most common enteric fever in low to middle income countries. In the pediatric population, it is a rare cause of acalculous cholecystitis in which one of the dreaded complication is gall bladder perforation. This was a case of a 15-year-old male with 1-month history of intermittent undocumented fever, anorexia and weight loss. The patient presented with signs of pancytopenia and abdominal examination revealed acute abdomen. Patient was optimized and prepared for surgery. Intraoperative findings revealed Type II gall bladder perforation with bile peritonitis, and patient underwent exploratory laparotomy, cholecystectomy, lavage, Jackson-Pratt drain. The sepsis eventually resolved postoperatively, and the patient was discharged. Preoperative diagnosis in patients with gall bladder perforation is often challenging and sophisticated, due to its rarity. However, it should be considered as one of the differential diagnoses in pediatric patients presenting with atypical history of abdominal pain. At present, there are no specific guidelines in the management of complications such as gall bladder perforation in patients with typhoid fever. Therefore, early diagnosis and immediate surgical intervention of gall bladder perforation are of prime importance in the successful outcomes of these patients, given the high morbidity and mortality associated with this condition.



2018 ◽  
Vol 5 (5) ◽  
pp. 1943 ◽  
Author(s):  
Nikhil Deshmukh ◽  
Alok Rath ◽  
Sridhar Reddy M. ◽  
Naresh M.

Among the atypical manifestations of dengue fever, comprising 15.8% of all cases, acalculous cholecystitis forms a small subset. Acalculous cholecystitis is managed conservatively in majority of cases and a chance of gall bladder perforation is low (2-18%). Management of gall bladder perforation in the scenario of Dengue is sometimes complicated by presence of thrombocytopenia and its complications thereof. Mortality associated with gall bladder perforation is relatively high. Gallbladder usually perforates at the fundus and is to be dealt with surgically if it doesn’t localize. Laparoscopic management of gall bladder perforation is feasible as calot’s is relatively virgin (as there is no calculous disease). Thorough peritoneal toileting is possible and a chance of intra-abdominal abscess in post-operative period is a mere speculation. Laparoscopic management results in early recovery and fewer wound complications and lesser hospital stay.   



2010 ◽  
Vol 15 (4) ◽  
pp. 139 ◽  
Author(s):  
ParagJ Karkera ◽  
Gursev Sandlas ◽  
Ritesh Ranjan ◽  
Abhaya Gupta ◽  
Paras Kothari




2013 ◽  
Vol 32 (3) ◽  
pp. 221-228
Author(s):  
Ganesh Kumar Rai ◽  
Subhana Karki ◽  
Bina Prajapati

Introduction: Enteric fever is a public health problem in developing countries including Nepal. Antimicrobial sensitivity pattern of Salmonella sp causing enteric fever is changing over time and also differs according to geographical location. Periodic surveillance of antimicrobial resistance of Salmonella sp is mandatory for management of enteric fever rationally. The objective of this study was to analyze the resistance pattern of Salmonella sp to commonly used antimicrobials. Materials and Methods: This was a retrospective study undertaken reviewing the records of blood isolates of Salmonella sp over one year period at Kanti Children’s Hospital, Nepal. Antimicrobial sensitivity testing was done following Kirby Bauer’s disk diffusion technique using Muller Hinton agar. Results: Salmonella typhi was found to be 100% resistance to ampicillin and resistance to nalidixic acid and ciprofloxacin was also high. The resistance to chloramphenicol and ofloxacin was low. No resistance was found to amoxicillin, ceftriaxone, cefotaxime and amikacin. However, among the sensitive isolates of Salmonella typhi intermediate sensitivity to ceftriaxone and ceftazidime was reported to be high. Among the isolates of S paratyphi A, the resistance to nalidixic acid was 100% followed by 75% to ciprofloxacin. No resistance was found to chloramphenicol, ceftriaxone, cefixime, amikacin and low resistance to amoxicillin and ofloxacin. Among the sensitive isolates of S paratyphi A, majority of them were only moderately sensitive to cefotaxime and ceftazidime and about 1/3 of the organisms had only intermediate sensitivity to ceftriaxone. Conclusiion: Commonly used parenteral third generation cephalosporins, first line drugs like chloramphenicol and amoxicillin and ofloxacin among fluoroquinolones were found to be effective in vitro in treating enteric fever. However, Salmonella typhi was found to be highly resistant to the most frequently used drugs like ciprofloxacin and cefixime and Salmonella paratyphi A to ciprofloxacin. A comparative chart of antimicrobial sensitivity of enteric fever in children over 10 year period from different hospitals of Kathmandu valley is also presented in the study. DOI: http://dx.doi.org/10.3126/jnps.v32i3.6625 J. Nepal Paediatr. SocVol.32(3) 2012 221-228



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