scholarly journals Current Use of Automatic Retinal Oximetry – a Review

2020 ◽  
Vol 76 (1) ◽  
pp. 3-11
Author(s):  
Petra Hübnerová ◽  
Petr Mlčák ◽  
Irena Šínová ◽  
Marta Karhanová ◽  
Martin Šín
Keyword(s):  
Oxygen Saturation ◽  
Retinal Vein Occlusion ◽  
Interdisciplinary Cooperation ◽  
Eye Diseases ◽  
Systemic Diseases ◽  
High Reproducibility ◽  
Non Invasive ◽  
Vein Occlusion ◽  
Pathological Mechanism ◽  
Retinal Oximetry

Purpose: To inform about possible use of the automatic retinal oximetry for the retinal oxygen saturation measurement in the eye and systemic diseases. Methods: We performed a literature review dealing with issues of retinal oxygen saturation monitoring by dual non-invasive retinal oximetry Oxymap T1 (Oxymap ehf. Reykjavík, Iceland). Results: We have found two main strains writing our paper on retinal oxygen saturation eye diseases. The first section concerns diseases created by having hypoxia as its main pathological factor - for example diabetes mellitus and retinal vein occlusion. The second group deals with atrophy as the main pathological mechanism which is typical for decreasing retinal oxygen consumption – for example glaucoma or retinitis pigmentosa (the second one named is not included in our work). Oximetry in systemic diseases creates a relatively new chapter of this branch with a very big potential of interdisciplinary cooperation for the future. It is possible the cooperation will not only include diabetologists but also neurologists (for example, in diseases like sclerosis multiplex or Devic‘s, Alzheimer‘s and Parkinson‘s disease) and haematologists (retinal oxygen saturation changes in patients with different rheological attributes of blood). Conclusion: Retinal oxygen saturation measuring by automatic retinal oximetry is a relatively new method with scientifically confirmed high reproducibility of results. Currently it is the only experimental method with vast potentials not only in the realm of the possibility of observing eye diseases (diabetic retinopathy, retinal vein occlusion or glaucoma) but also in developing interdisciplinary cooperation with diabetologists, neurologists and haematologists.

Clinical implications of retinal oximetry in retinal vein occlusion: a review

2021 ◽  
Author(s):  
Aditya V. Belamkar ◽  
Sayena Jabbehdari ◽  
Alon Harris ◽  
Amir R. Hajrasouliha
Keyword(s):  
Retinal Vein Occlusion ◽  
Clinical Implications ◽  
Vein Occlusion ◽  
Retinal Oximetry

scholarly journals Retinal oximetry in branch retinal vein occlusion

2019 ◽  
Vol 97 (6) ◽  
Author(s):  
Rie Osaka ◽  
Yuki Nakano ◽  
Yukari Takasago ◽  
Tomoyoshi Fujita ◽  
Ayana Yamashita ◽  
...  
Keyword(s):  
Retinal Vein Occlusion ◽  
Branch Retinal Vein Occlusion ◽  
Vein Occlusion ◽  
Retinal Oximetry

scholarly journals Oxygen saturation in branch retinal vein occlusion

2011 ◽  
Vol 90 (5) ◽  
pp. 466-470 ◽  
Author(s):  
Sveinn Hakon Hardarson ◽  
Einar Stefánsson
Keyword(s):  
Oxygen Saturation ◽  
Retinal Vein Occlusion ◽  
Branch Retinal Vein Occlusion ◽  
Vein Occlusion

scholarly journals Changes in retinal venular oxygen saturation predict activity of proliferative diabetic retinopathy 3 months after panretinal photocoagulation

2017 ◽  
Vol 102 (3) ◽  
pp. 383-387 ◽  
Author(s):  
Thomas Lee Torp ◽  
Ryo Kawasaki ◽  
Tien Yin Wong ◽  
Tunde Peto ◽  
Jakob Grauslund
Keyword(s):  
Diabetic Retinopathy ◽  
Oxygen Saturation ◽  
Proliferative Diabetic Retinopathy ◽  
Panretinal Photocoagulation ◽  
Wide Field ◽  
Non Invasive ◽  
Venous Oxygen Saturation ◽  
Treatment Naïve ◽  
Angiographic Findings ◽  
Retinal Oximetry

Background/AimsProliferative diabetic retinopathy (PDR) is a severe blinding condition. We investigated whether retinal metabolism, measured by retinal oximetry, may predict PDR activity after panretinal laser photocoagulation (PRP).MethodsWe performed a prospective, interventional, clinical study of patients with treatment-naive PDR. Wide-field fluorescein angiography (OPTOS, Optomap) and global and focal retinal oximetry (Oxymap T1) were performed at baseline (BL), and 3 months (3M) after PRP. Angiographic findings were used to divide patients according to progression or non-progression of PDR after PRP. We evaluated differences in global and focal retinal oxygen saturation between patients with and without progression of PDR after PRP treatment.ResultsWe included 45 eyes of 37 patients (median age and duration of diabetes were 51.6 and 20 years). Eyes with progression of PDR developed a higher retinal venous oxygen saturation than eyes with non-progression at 3M (global: +5.9% (95% CI –1.5 to 12.9), focal: +5.4%, (95% CI –4.1 to 14.8)). Likewise, progression of PDR was associated with a lower arteriovenular (AV) oxygen difference between BL and 3M (global: –6.1%, (95% CI –13.4 to –1.4), focal: –4.5% (95% CI –12.1 to 3.2)). In a multiple logistic regression model, increment in global retinal venular oxygen saturation (OR 1.30 per 1%-point increment, p=0.017) and decrement in AV oxygen saturation difference (OR 0.72 per 1%-point increment, p=0.016) at 3M independently predicted progression of PDR.ConclusionDevelopment of higher retinal venular and lower AV global oxygen saturation independently predicts progression of PDR despite standard PRP and might be a potential non-invasive marker of angiogenic disease activity.

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