scholarly journals Synthesis and Characterization of New Etodolac Derivatives with Possible Anti-Inflammatory Activity

2019 ◽  
Vol 28 (1) ◽  
pp. 107-113
Author(s):  
Omeed Muhsin Hassan ◽  
Susan Sarsam
Keyword(s):  
Ir Spectroscopy ◽  
Egg White ◽  
Inflammatory Activity ◽  
Synthesis And Characterization ◽  
Paw Edema ◽  
Ft Ir ◽  
Anti Inflammatory ◽  
Ft Ir Spectroscopy ◽  
Inflammatory Effect

A series of Etodolac hydrazone derivatives were synthesized and evaluated for their anti-inflammatory activity by using egg white induced paw edema method. All the synthesized target compounds were characterized by CHN- microanalysis, FT-IR spectroscopy and 1HNMR analysis. The synthesized target compounds (P1-P3) were found to be active in reducing paw edema thickness and their anti-inflammatory effect was comparable to that of the standard (Etodolac). Keywords: Etodolac hydrazone derivatives, anti-inflammatory, paw edemamethod.

scholarly journals Synthesis, Characterization and Preliminary Anti-inflammatory Evaluation of New Fenoprofen Hydrazone Derivatives

2020 ◽  
Vol 29 (2) ◽  
pp. 239-244
Author(s):  
Hayder M. Abdulhamza ◽  
Muthanna S. Farhan
Keyword(s):  
Ir Spectroscopy ◽  
Egg White ◽  
Inflammatory Activity ◽  
Paw Edema ◽  
Ft Ir ◽  
Anti Inflammatory ◽  
Multistep Reaction ◽  
Derivatives Of ◽  
Ft Ir Spectroscopy ◽  
Inflammatory Effect

New hydrazone derivatives of Fenoprofen were synthesized and evaluated for their anti-inflammatory activity by means of egg white induced paw edema method. All the synthesized target compounds were characterized by FT-IR spectroscopy, 1HNMR analysis and by measure of their physical properties. The synthesis of the target compounds(H1-H4) was accomplished by multistep reaction procedures. The synthesized target compounds were show activity in reducing paw edema thickness and their anti-inflammatory effect was comparable to that of the standard (Fenoprofen) except for compound H3 which show anti-inflammatory activity higher than Fenoprofen.

scholarly journals Synthesis, Characterization and Preliminary Anti-inflammatory Evaluation of New Etodolac Derivatives

2019 ◽  
Vol 28 (1) ◽  
pp. 106-112
Author(s):  
Omeed M. Hassan ◽  
Susan W. Sarsam
Keyword(s):  
Ir Spectroscopy ◽  
Egg White ◽  
Inflammatory Activity ◽  
Paw Edema ◽  
Ft Ir ◽  
Anti Inflammatory ◽  
Multistep Reaction ◽  
Derivatives Of ◽  
Ft Ir Spectroscopy ◽  
Inflammatory Effect

Three new hydrazone derivatives of Etodolac were synthesized and evaluated for their anti-inflammatory activity by using egg white induced paw edema method. All the synthesized target compounds were characterized by CHN- microanalysis, FT-IR spectroscopy, and 1HNMR analysis. The synthesis of the target (P1-P3) compounds was accomplished following multistep reaction procedures. The synthesized target compounds were found to be active in reducing paw edema thickness and their anti-inflammatory effect was comparable to that of the standard (Etodolac).

Electrochemically Synthesis and Characterization of Copolymers Based on 1, 4-Diethoxybenzene and 3, 4-Ethylenedioxythiophene

2011 ◽  
Vol 335-336 ◽  
pp. 989-993
Author(s):  
Mi Ouyang ◽  
Zhen Wei Yu ◽  
Yi Xu ◽  
Yu Jian Zhang ◽  
Cheng Zhang
Keyword(s):  
Cyclic Voltammetry ◽  
Ir Spectroscopy ◽  
Feed Ratio ◽  
Synthesis And Characterization ◽  
Monomer Mixture ◽  
Long Wavelength ◽  
H Nmr ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

Copolymers based on 1, 4-diethoxybenzene (DEB) and 3, 4-ethylenedioxythiophene (EDOT) were electrochemically synthesized and characterized. The structures of the copolymers were established by 1H NMR and FT-IR spectroscopy. The results indicated the final product was a copolymer instead of a blend or a composite. The physical properties were systematically investigated by cyclic voltammetry, UV-vis absorption and fluorescence. The PL maximum of copolymers presented obviously red-shift to long wavelength as the feed ratio of EDOT in monomer mixture increased.

SYNTHESIS AND CHARACTERIZATION OF POLYURETHANE ACRYLATES FOR UV CURABLE COATING AGENTS

2007 ◽  
Vol 14 (04) ◽  
pp. 713-717
Author(s):  
MI NA PARK ◽  
YOUNG SOO KANG ◽  
SUN WHA OH ◽  
BYUNG HYUN AHN ◽  
MYUNG JUN MOON
Keyword(s):  
Ir Spectroscopy ◽  
Chain Transfer ◽  
Synthesis And Characterization ◽  
Dibutyltin Dilaurate ◽  
Urethane Acrylate ◽  
Uv Curable ◽  
Ft Ir ◽  
Coating Agents ◽  
Ft Ir Spectroscopy

The single hydroxyl-terminated urethane acrylate oligomers were synthesized from 2-mercaptoethanol (2-MEOH), alkyl (methyl, butyl, and 2-ethylhexyl) acrylate, and 2,2-azobisisobutyronitrile (AIBN, initiator), with dibutyltin dilaurate (DBTDL) as a catalyst. 2-MEOH was used as a functional chain transfer agent. Poly(alkyl urethane) acrylate oligomers were obtained by the reaction of single hydroxyl-terminated polyalkyl acrylates and 2-isocyanatoethyl acrylate. They were characterized by NMR, FT-IR spectroscopy, rheometer, and DSC. Because poly(alkyl urethane) acrylate oligomers have lower Tg and viscosity than hydroxyl-terminated polyalkyl acrylate oligomers (HTPAO) non-containing urethane groups, they can be used for ultraviolet (UV) curable coatings, inks, and adhesives.

Synthesis and characterization of Ni(ii)–Vanillin–Schiff base–MCM-41 composite as an efficient and reusable nanocatalyst for multicomponent reactions

RSC Advances ◽  
2016 ◽  
Vol 6 (61) ◽  
pp. 56549-56561 ◽  
Author(s):  
Mohsen Nikoorazm ◽  
Arash Ghorbani-Choghamarani ◽  
Maryam Khanmoradi
Keyword(s):  
Schiff Base ◽  
Ir Spectroscopy ◽  
Multicomponent Reactions ◽  
Synthesis And Characterization ◽  
Icp Oes ◽  
Ft Ir ◽  
Mcm 41 ◽  
Ft Ir Spectroscopy

Ni(ii)–Vanillin–Schiff base–MCM-41 has been synthesized and characterized by XRD, TGA, BET, EDS, SEM, ICP-OES, TEM and FT-IR spectroscopy. This nanostructural catalyst has been applied for multicomponent reactions.

Synthesis and characterization of Cu(II)-halide 1-methylimidazole complexes

2016 ◽  
Vol 71 (2) ◽  
pp. 105-112 ◽  
Author(s):  
Michael Hörmannsdorfer ◽  
Ulrike Kahl ◽  
Tom Nilges
Keyword(s):  
Mass Spectrometry ◽  
Ir Spectroscopy ◽  
Single Crystal ◽  
Thermal Analyses ◽  
Synthesis And Characterization ◽  
X Ray Diffraction ◽  
X Ray ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

AbstractThree new complexes of Cu(II) halides (Cl, Br) with 1-methylimidazole (MIm), [Cu(MIm)4]Br2 (1), [Cu(MIm)4Br]Br · H2O (2), and [Cu(MIm)6]Cl2 · 2H2O (3) have been synthesized in ethanol. Their crystal structures have been determined by single-crystal X-ray diffraction. FT-IR spectroscopy, mass spectrometry, and thermal analyses were applied to characterize the compounds.

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