scholarly journals Accuracy of Fine Needle Aspiration Cytology in Solitary or Dominant Nodular Goitre: A Single Centre Study

2020 ◽  
Vol 16 (2) ◽  
Author(s):  
M. Rohaizak ◽  
Y Aman Fuad ◽  
I Naqiyah ◽  
J.J Saladina ◽  
A.S Shahrun Niza
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Nodular Goitre ◽  
Fine Needle ◽  
Single Centre Study ◽  
Histology Result ◽  
Needle Aspiration Cytology ◽  
Large Goitre

Background: Thyroid swelling or goitre is a common condition, either asymptomatic or symptomatic. The diagnosis is usually established by ultrasound or fine needle aspiration cytology (FNAC) as a gold standard. The sensitivity of the test is inversely related to increasing size of the nodule. The objective of this study is to evaluate the accuracy of FNAC especially in cases of large goitre. Material and methods: This is a retrospective study on patients who underwent thyroidectomy between January 2000 to December 2007 for solitary or dominant nodular goitre. The analysis was made only on those patients with complete data on FNAC and histology. Result: There were 235 patients, but only 161 patients were analysed after excluding the suspicious and inadequate sample. The patients’ mean age was 42.1 year old (21 to 60). The size of the thyroid nodule ranged from 2.1 to 5.0 cm (mean = 3.9 cm). The overall sensitivity was 67.4% and the overall accuracy was 86.3%. The accuracy of FNAC according to the sizes above and below the value were as follows; 2 cm (72.2% vs. 88.1%); 3 cm (88.0% vs. 87.4%) ; 4 cm (86.6% vs. 84.4%) ; 5 cm (87.3% vs. 78.8%). This was most obvious in the sensitivity of the FNA which also showed reducing trend as the nodules increased in size. Conclusion: FNAC is an essential diagnostic tool in the management of nodular goitre. Our study showed that the accuracy of FNAC decreased as the size of the nodule getting bigger. Cautious approach should be taken in the management of large goitre and decision should not be based only on the result of FNAC.

scholarly journals UTILITY OF FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) AS A SCREENING TOOL IN DIAGNOSIS OF THYROID LESION IN CORRELATION WITH HISTOPATHOLOGY – A 4 YEARS STUDY

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. B.Naga Raja ◽  
Dr. G.Sobha Rani ◽  
Dr. V.Nagesh Kumar
Keyword(s):  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Medullary Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Nodular Goitre ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Common Malignancy

Background: Fine needle aspiration cytology (FNAC) has been proved to be a safe, cost effective, good screening and quick procedure for early diagnosis. Aim of study: To categorise various thyroid lesions To confirm preoperative suspected malignant cases Methods: This is a prospective study done over a period of four years from 2015 -2018. A total of 274 thyroid cases attending the outpatient department in Government General Hospital, Kadapa were sent for FNAC to the Department of Pathology, all these cases were categorised based on cyto- morphological features obtained on FNAC and later correlated with Histopathological findings. Results: 44 (16.08%) cases were categorised as inflammatory lesion. 208 (75.91%) cases were categorised as functional disorders like nodular goitre, nodular goitre with cystic degeneration. 10 (3.64%) cases were categorised as follicular neoplasm. Most common malignancy was papillary carcinoma with 7 (2.55%) cases. Un common malignancy was medullary carcinoma 1(0.36%) case. Keywords:  FNAC, Kadapa, Medullary carcinoma, Papillary carcinoma

scholarly journals Correlation of Fine Needle Aspiration Cytology with Histopathological Findings in the Diagnosis of Thyroid Swellings – A One Year Study in a Tertiary Care Hospital, Hyderabad

2021 ◽  
Vol 8 (18) ◽  
pp. 1246-1251
Author(s):  
Keerthana Muppidi ◽  
Vidya Kedarisetti ◽  
Kanya Kumari Mahankali
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Nodular Goitre ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also done and correlated with FNAC findings. Sensitivity, specificity and accuracy were calculated. RESULTS Age of the patients varied from 20 - 69 yrs. Most of them were in the age group of 30 - 39 years and 50 - 59 years. The ratio of male to female was 1:4.9. Swelling of the neck was the most common presentation in most of the patients. On FNAC 33 (70.2 %) cases were diagnosed as colloid nodular goitre, 04 (8.5 %) as autoimmune thyroiditis, 08 (17.0 %) as follicular neoplasm, 01 (2.1 %) as suspicious of malignancy, 01 (2.1 %) as papillary carcinoma. On histopathological examination 25 (53.2 %) cases were diagnosed as colloid nodular goitre, 01 (2.1 %) as fibrous thyroiditis, 01 (2.1 %) as Graves’ disease, 07 (14.9 %) as Hashimoto’s’ thyroiditis, 06 (12.8 %) as follicular adenoma, 01 (2.1 %) as follicular carcinoma, 04 (8.5 %) as papillary carcinoma and 02 (4.2 %) as NIFTP (noninvasive follicular thyroid neoplasm with papillary like nuclear features). The overall sensitivity was 69.2 %, specificity was 97.0 % and accuracy was 89.3 %. CONCLUSIONS FNAC is a minimally invasive, highly accurate and cost-effective procedure. FNAC helps the clinician to diagnose malignant lesions with confidence. It has high rates of specificity and accuracy but comparatively has less sensitivity. However, it is very important for the management of patients with thyroid swelling. KEYWORDS Fine Needle Aspiration, Prospective Study, Sensitivity, Specificity, Thyroid Swelling

Role of fine needle aspiration cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118

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