scholarly journals Revolute-Leaf, a New Completely Dominant Mutant in Peanut

2018 ◽  
Author(s):  
William D. Branch
Keyword(s):  
Dominant Mutant

Developmental Morphology of the Skin and Hair Follicles in Normal and in “Ragged” Mice

Development ◽  
1962 ◽  
Vol 10 (4) ◽  
pp. 507-529
Author(s):  
J. Slee
Keyword(s):  
Hair Growth ◽  
Mutant Gene ◽  
Hair Follicles ◽  
Mutant Mice ◽  
Developmental Morphology ◽  
Adult Morphology ◽  
Dominant Mutant

Ragged (Ra) is a semi-dominant mutant gene which was first reported by Carter & Phillips (1954). The adult morphology, the genetics, and the embryology of the mutant mice were described by Slee (1957 a, b). It was found that adult ragged heterozygotes (Ra+) had sparser coats than normal, many of their hair follicles being incompletely developed and non-functional. Ragged homozygotes (RaRa) were almost naked. Most of their pelage hair follicles were either absent, or abnormal and non-functional. Ra+ embryos could be identified from 16 days' gestation by the retardation of their sinus hair-growth. RaRa embryos were characterized from 13 days' gestation by the occurrence of a generalized subcutaneous oedema which persisted until birth, and also by retardation in the development of their sinus hairs and follicles. Pelage follicle primordia appeared at the normal time (14 days' gestation) in Ra+ and RaRa embryos but subsequently developed slowly in RaRa embryos, especially when the oedema was pronounced.

scholarly journals trans-Dominant and non-trans-dominant mutant simian virus 40 large T antigens show distinct responses to ATP.

1997 ◽  
Vol 71 (10) ◽  
pp. 7549-7559 ◽  
Author(s):  
A M Castellino ◽  
P Cantalupo ◽  
I M Marks ◽  
J V Vartikar ◽  
K W Peden ◽  
...  
Keyword(s):  
Simian Virus 40 ◽  
Simian Virus ◽  
T Antigens ◽  
Dominant Mutant

Dominant maternal-effect mutations causing embryonic lethality in Caenorhabditis elegans.

Genetics ◽  
1990 ◽  
Vol 125 (2) ◽  
pp. 351-369 ◽  
Author(s):  
P E Mains ◽  
I A Sulston ◽  
W B Wood
Keyword(s):  
Caenorhabditis Elegans ◽  
Maternal Effect ◽  
Gene Dosage ◽  
Recessive Mutation ◽  
Dominant Male ◽  
Temperature Sensitive ◽  
Male Mating ◽  
Loss Of Function ◽  
Dominant Mutant ◽  
Embryonic Viability

Abstract We undertook screens for dominant, temperature-sensitive, maternal-effect embryonic-lethal mutations of Caenorhabditis elegans as a way to identify certain classes of genes with early embryonic functions, in particular those that are members of multigene families and those that are required in two copies for normal development. The screens have identified eight mutations, representing six loci. Mutations at three of the loci result in only maternal effects on embryonic viability. Mutations at the remaining three loci cause additional nonmaternal (zygotic) effects, including recessive lethality or sterility and dominant male mating defects. Mutations at five of the loci cause visible pregastrulation defects. Three mutations appear to be allelic with a recessive mutation of let-354. Gene dosage experiments indicate that one mutation may be a loss-of-function allele at a haploin sufficient locus. The other mutations appear to result in gain-of-function "poison" gene products. Most of these become less deleterious as the relative dosage of the corresponding wild-type allele is increased; we show that relative self-progeny viabilities for the relevant hermaphrodite genotypes are generally M/+/+ greater than M/+ greater than M/M/+ greater than M/Df greater than M/M, where M represents the dominant mutant allele.

A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants

1997 ◽  
Vol 15 (5) ◽  
pp. 444-447 ◽  
Author(s):  
Jack Q. Wilkinson ◽  
Michael B. Lanahan ◽  
David G. Clark ◽  
Anthony B. Bleecker ◽  
Caren Chang ◽  
...  
Keyword(s):  
Mutant Receptor ◽  
Dominant Mutant ◽  
Ethylene Insensitivity

scholarly journals Detrimental genes with partial selfing and effects on a neutral locus

1974 ◽  
Vol 23 (2) ◽  
pp. 191-200 ◽  
Author(s):  
Tomoko Ohta ◽  
C. Clark Cockerham
Keyword(s):  
Linkage Disequilibrium ◽  
Mutational Load ◽  
Complete Linkage ◽  
Single Mutant ◽  
Infinite Population ◽  
Neutral Locus ◽  
Dominant Mutant ◽  
Self Fertilization ◽  
Recessive Mutant ◽  
Mutant Genes

SUMMARYGene and genotypic frequencies for a deleterious mutant in mutation selection balance are derived for an infinite population undergoing partial self-fertilization. These provide formulations of mean survival and the mutational load. Obtained also are the average number of mutant genes and affected individuals stemming from a single mutant.As a concomitant effect on frequencies at a neutral locus the mutational load is distributed disproportionately among the neutral genotypes. For partially recessive mutant genes on the 1, 1-sh, 1-s scale, the effect is to increase the frequency of the heterozygote and to decrease the frequencies of homozygotes at the neutral locus relative to the frequencies expected with complete neutrality. This apparent overdominance at the neutral locus has been shown to be connected with identity disequilibrium rather than linkage disequilibrium. It increases generally as s and h decrease, and as the proportion of self-fertilization and the degree of linkage increase. The apparent overdominance with complete linkage is generally less than double that for free recombination. For partially dominant mutant genes, h ≥ ½, the effects on the frequencies of heterozygote and homozygotes at the neutral locus are reversed.

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