scholarly journals Huge Hepatocellular Adenoma

Author(s):  
Tomas Urbonas ◽  
Andrei Ryllo ◽  
Tomas Urbonas

Hepatocellular adenoma (HCA) is generally uncommon benign liver tumor with potential to become malignant. Its prevalence has been increasing steadily secondary to wide use of oral contraceptives and due to the increased use of imaging for a variety of unrelated reasons. Large adenomas may present with chronic abdominal pain. As HCA become larger it is prone to rupture and hemorrhage due to central necrosis because the vascular supply is limited to the surface of the tumor. If left untreated HCA can undergo transformation into hepatocellular carcinoma which can be as high as in 10% of cases1 or even higher. Surgical excision is a preferred method of treatment. Other modalities include embolization of bleeding tumors and ablative modalities in selected cases.

1993 ◽  
Vol 34 (4) ◽  
pp. 392-394 ◽  
Author(s):  
T. Murakami ◽  
H. Nakamura ◽  
S. Hori ◽  
K. Nakanishi ◽  
T. Mitani ◽  
...  

Angiomyolipoma, a rare benign liver tumor, was observed in a 50-year-old woman examined with US, CT, MR imaging and angiography. Dynamic studies using CT and MR imaging were valuable in differentiating the disease from hepatocellular carcinoma with fat deposits.


2015 ◽  
Vol 60 (1) ◽  
pp. 173-177 ◽  
Author(s):  
Oskar Kornasiewicz ◽  
Michał Grąt ◽  
Krzysztof Dudek ◽  
Zbigniew Lewandowski ◽  
Zuzanna Gorski ◽  
...  

2002 ◽  
Vol 37 (10) ◽  
pp. 1237-1240 ◽  
Author(s):  
H.-J. Gassel ◽  
I. Klein ◽  
W. Timmermann ◽  
W. Kenn ◽  
A. M. Gassel ◽  
...  

1923 ◽  
Vol 19 (6) ◽  
pp. 10-18
Author(s):  
M. I. Goldstein

The recognition of a benign liver tumor in an intact abdominal wall is often a very difficult and sometimes even impossible task for the therapists. This rarity of the disease gives us grounds to dwell on a case of benign liver tumor, which we observed in the Therapeutic Department of Kaz. Clinical Institute.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jing Han ◽  
Marius C. van den Heuvel ◽  
Hironori Kusano ◽  
Koert P. de Jong ◽  
Annette S. H. Gouw

The inflammatory type hepatocellular adenoma (IHCA) is a subtype of HCA which is a benign liver tumor, predominantly occurring in young women in an otherwise normal liver. IHCA contains either a mutation of gp130 or STAT3. Both mutations lead to a similar morphologic phenotype and to increased expression of C-reactive protein (CRP) and/or serum amyloid-A (SAA). IHCA comprised about 40% of all HCAs and is associated with obesity. We investigated the histomorphological and immunophenotypical changes of the nontumorous liver of 32 resected IHCA specimens. Similar types of changes are present in samples taken adjacent to tumor and distant ones. The lobular architecture is well preserved. Mild/moderate steatosis is found in a high frequency which is in accordance with the median BMI of 32 in our cases. Of note are the regular findings of sinusoidal dilatation, single arteries, and minute CRP foci which are all features of HCA. These distinct CRP foci are mostly found in cases of multiple IHCA which indicates that the remnant liver may also contain IHCA foci. These findings show that the nonlesional liver in IHCA does contain abnormalities, and this may have consequences for the followup, especially since it is known that obesity may stimulate malignant growth.


1978 ◽  
Vol 6 (2) ◽  
pp. 119-120 ◽  
Author(s):  
Christian V. Cimmino ◽  
David W. Scott

2007 ◽  
Vol 42 (6) ◽  
pp. 1141-1145 ◽  
Author(s):  
Sanjeev Dutta ◽  
Deepika Nehra ◽  
Russell Woo ◽  
Inbal Cohen

2019 ◽  
pp. 76-85
Author(s):  
B. M. Medvedeva ◽  
D. M. Khaitsman ◽  
A. B. Lukianchenko ◽  
E. A. Moroz

Hepatocellular adenoma (HCA) is the uncommon benign liver tumor, which is characterized by monoclonal proliferation of mature hepatocytes. HCAs have many genetic and molecular features that determine their natural behavior (such as malignant transformation), but MRI features are studied just for two subtypes (H-HCA и I-ICA). This article presents clinical case of 58 y.o. woman with hepatitis C, hepatic adenomatosis and malignant transformation of one of multiple HCAs.


2010 ◽  
Vol 4 (3) ◽  
pp. 463-467
Author(s):  
Napa Parinyanitikul ◽  
Laddawan Vajragupta ◽  
Naruemon Klaikaew ◽  
Boonchoo Sirichindakul ◽  
Virote Sriuranpong

Abstract Background: Liver is the most common distant metastasized organ in advanced colon cancer. Surgical resection of metastatic lesions would offer the best chance of a long-term survival. An accurate diagnosis and evaluation of extent of disease is crucial in the management of liver metastasis. Objective: Report a benign hepatic condition mimicking liver metastasis in a colon cancer patient. Case presentation: A 53-year-old male with an early stage sigmoid colon cancer was treated with sigmoidectomy followed by adjuvant chemotherapy consisting of 5-FU, leucovorin, and oxaliplatin for six months. Annual computerized tomography of abdomen at two years after the surgery revealed three hypervascular nodules in the liver. Investigations including MRI of the liver and whole body FDG-F18 PET/CT demonstrated evidence consistent with non-metastatic liver nodules. Liver biopsy of one of the lesions led to the diagnosis of “focal nodular hyperplasia”. Conclusion: The possible etiology, diagnosis, and further management of this benign liver tumor, the focal nodular hyperplasia became clear.


Sign in / Sign up

Export Citation Format

Share Document