Orphan designation: Pegylated recombinant human interleukin-10, Treatment of pancreatic cancer

2018 ◽  
Author(s):  
Keyword(s):  
Pancreatic Cancer ◽  
Interleukin 10 ◽  
Orphan Designation

Inhibition of Interleukin-10 in the tumor microenvironment can restore mesothelin chimeric antigen receptor T cell activity in pancreatic cancer in vitro

Surgery ◽  
2018 ◽  
Vol 163 (3) ◽  
pp. 627-632 ◽  
Author(s):  
Ramesh B. Batchu ◽  
Oksana V. Gruzdyn ◽  
Ebrahem M. Mahmud ◽  
Fatme Chukr ◽  
Rajesh Dachepalli ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
T Cell ◽  
Tumor Microenvironment ◽  
Chimeric Antigen Receptor ◽  
Cell Activity ◽  
Antigen Receptor ◽  
Interleukin 10

A Vaccinia Virus Armed with Interleukin-10 Is a Promising Therapeutic Agent for Treatment of Murine Pancreatic Cancer

2014 ◽  
Vol 21 (2) ◽  
pp. 405-416 ◽  
Author(s):  
Louisa S. Chard ◽  
Eleni Maniati ◽  
Pengju Wang ◽  
Zhongxian Zhang ◽  
Dongling Gao ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Vaccinia Virus ◽  
Therapeutic Agent ◽  
Interleukin 10 ◽  
Promising Therapeutic Agent
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