Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia

2019 ◽  
Author(s):  
Keyword(s):  
Platelet Rich Plasma ◽  
Occipital Neuralgia ◽  
Ultrasound Guided ◽  
Post Traumatic

scholarly journals Ultrasound guided platelet rich plasma injections for post-traumatic greater occipital neuralgia: a randomized controlled pilot study

2021 ◽  
Author(s):  
Jacqueline Stone ◽  
Tak S. Fung ◽  
Matthew Machan ◽  
Christina Campbell ◽  
Rodney Li Pi Shan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Adverse Events ◽  
Normal Saline ◽  
Platelet Rich Plasma ◽  
Occipital Neuralgia ◽  
Greater Occipital Nerve ◽  
Post Traumatic ◽  
The Impact

Abstract Background: Post-traumatic headaches (PTH) are a common sequalae of TBI and greatly impact patient function and quality of life. Post-traumatic greater occipital neuralgia (GON) is a type of post-traumatic headache. Conventional treatment includes steroid/anesthetic injections which typically alleviate pain but have a short duration of effect. Platelet rich plasma (PRP) is an emerging biological treatment for numerous degenerative disorders, including peripheral nerve disorders. The primary aim of this pilot study is to evaluate whether a randomized control trial of PRP for the treatment of GON in patients with post-traumatic headaches is feasible in regard to recruitment, adherence, retention, and adherence and adverse events. Exploratory aims includes improvement in pain, function and quality of life in patients with post-traumatic GON receiving PRP compared to steroid/anesthetic and normal saline injections. Methods: Thirty adults (over 18 years of age) with post-traumatic GON will be randomized into one of three groups: 1) autologous PRP injection 2) steroid/anesthetic injection (standard care) or 3) placebo injection with normal saline. Injections will be performed to the greater occipital nerve under ultrasound guidance by a trained physician. Daily headache intensity and frequency data will be collected pre-injection and for the duration of the study period. Feasibility will be defined as greater than 30% recruitment, 70% completion of intervention, 70% retention and less than 2 minor adverse events. Exploratory outcomes will be explored using the (HIT-6; a valid and reliable 6-item questionnaire for assessment of the impact of headaches across different diagnostic groups of headaches (42, 43)) and the quality of life in following brain injury questionnaire (QOILIBRI). Discussion: This pilot study will be the first to evaluate the feasibility of PRP as a potential treatment of GON in patients with post-traumatic headache. Trial Registration: ClinicalTrials.gov - NCT04051203 (registered August 9, 2019), available at https://clinicaltrials.gov/ct2/show/NCT04051203?cond=greater+occipital+neuralgia&draw=2&rank=1

Ultrasound Guided Platelet rich Plasma Injections for Post-Traumatic Greater Occipital Neuralgia: A Randomized Controlled trial Protocol

2021 ◽  
Author(s):  
Jacqueline Stone ◽  
Tak S. Fung ◽  
Matthew Machan ◽  
Christina Campbell ◽  
Rodney Li Pi Shan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brain Injury ◽  
Normal Saline ◽  
Rating Scale ◽  
Platelet Rich Plasma ◽  
Occipital Neuralgia ◽  
Headache Intensity ◽  
Greater Occipital Nerve ◽  
Post Traumatic

Abstract Background: Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Post-traumatic headaches (PTH) are a common sequalae of TBI and greatly impact patient function and quality of life. Post-traumatic greater occipital neuralgia (GON) is a type of post-traumatic headache. Conventional treatment includes steroid/anesthetic injections which typically alleviate pain, but have a short duration of effect. Platelet rich plasma (PRP) is an emerging biological treatment for numerous degenerative disorders, including peripheral nerve disorders. The primary aim of this study is to evaluate the pain response of a single perineural PRP injection in the treatment of post-traumatic GON.Methods: Thirty adults (over 18 years of age) with post-traumatic GON will be randomized into one of three groups: 1) autologous PRP injection 2) steroid/anesthetic injection (standard care) or 3) placebo injection with normal saline. Injections will be performed to the greater occipital nerve under ultrasound guidance by a trained physician. Daily headache intensity and frequency data will be collected pre-injection and for the duration of the study period. The primary outcome will be the change in headache intensity, as measured by a reduction on the numerical pain rating scale (NPRS) at 3 months post-injection in the PRP group, versus the normal saline and steroid groups. Secondary outcomes will include adverse effects, prn medication usage, and impact on function and quality of life as measured by the Headache Impact Test 6 (HIT-6) and Quality of Life following Brain Injury (QOILIBRI) questionnaires. Discussion: This trial will evaluate the efficacy of PRP injections as a treatment for post-traumatic GON. This research will further our understanding of PTH, GON, and the treatment of peripheral neuralgias.Trial Registration: ClinicalTrials.gov - NCT04051203 (registered August 9, 2019), available at https://clinicaltrials.gov/ct2/show/NCT04051203?cond=greater+occipital+neuralgia&draw=2&rank=1

scholarly journals Ultrasound-guided platelet-rich plasma injections for post-traumatic greater occipital neuralgia: study protocol for a pilot randomized controlled trial

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Jacqueline E. Stone ◽  
Tak S. Fung ◽  
Matthew Machan ◽  
Christina Campbell ◽  
Rodney Li Pi Shan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brain Injury ◽  
Pilot Study ◽  
Adverse Events ◽  
Normal Saline ◽  
Platelet Rich Plasma ◽  
Occipital Neuralgia ◽  
Post Traumatic ◽  
The Impact

Abstract Background Post-traumatic headaches (PTH) are a common sequelae of traumatic brain injury (TBI) and greatly impact patient function and quality of life. Post-traumatic greater occipital neuralgia (GON) is a type of post-traumatic headache. Conventional treatment includes steroid/anesthetic injections which typically alleviate pain but have a short duration of effect. Platelet-rich plasma (PRP) is an emerging biological treatment for numerous degenerative disorders, including peripheral nerve disorders. The primary aim of this pilot study is to evaluate whether a randomized control trial of PRP for the treatment of GON in patients with post-traumatic headaches is feasible in regard to recruitment, adherence, retention, and adherence and adverse events. Exploratory aims include improvement in pain, function, and quality of life in patients with post-traumatic GON receiving PRP compared to steroid/anesthetic and normal saline injections. Methods Thirty adults (over 18 years of age) with post-traumatic GON will be randomized into one of three groups: (1) autologous PRP injection, (2) steroid/anesthetic injection (standard care), or (3) placebo injection with normal saline. Injections will be performed to the greater occipital nerve under ultrasound guidance by a trained physician. Daily headache intensity and frequency data will be collected pre-injection and for the duration of the study period. Feasibility will be defined as greater than 30% recruitment, 70% completion of intervention, 70% retention, and less than 2 minor adverse events. Exploratory outcomes will be explored using the Headache Impact Test-6 (HIT-6, a valid and reliable 6-item questionnaire for assessment of the impact of headaches across different diagnostic groups of headaches) and the quality of life in following brain injury questionnaire (QOILIBRI). Discussion This pilot study will be the first to evaluate the feasibility of PRP as a potential treatment of GON in patients with post-traumatic headache. Trial registration ClinicalTrials.gov - NCT04051203 (registered August 9, 2019).

scholarly journals Treatment of Partial Rotator Cuff Tear with Ultrasound-guided Platelet-rich Plasma

2017 ◽  
Vol 7 ◽  
pp. 32 ◽  
Author(s):  
Vetrivel Chezian Sengodan ◽  
Sajith Kurian ◽  
Raghupathy Ramasamy
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Platelet Rich Plasma ◽  
Rotator Cuff Tears ◽  
Lateral Side ◽  
Ultrasound Guided ◽  
Cuff Tear ◽  
Plasma Injection ◽  
Partial Rotator Cuff Tear ◽  
Shoulder Score

Background: The treatment of symptomatic partial rotator cuff tear has presented substantial challenge to orthopaedic surgeons as it can vary from conservative to surgical repair. Researches have established the influence of platelet rich plasma in healing damaged tissue. Currently very few data are available regarding the evidence of clinical and radiological outcome of partial rotator cuff tear treated with ultrasound guided platelet rich plasma injection in English literature. Materials and Methods: 20 patients with symptomatic partial rotator cuff tears were treated with ultrasound guided platelet rich plasma injection. Before and after the injection of platelet rich plasma scoring was done with visual analogue score, Constant shoulder score, and UCLA shoulder score at 8 weeks and third month. A review ultrasound was performed 8 weeks after platelet rich plasma injection to assess the rotator cuff status. Results: Our study showed statistically significant improvements in 17 patients in VAS pain score, constant shoulder score and UCLA shoulder score. No significant changes in ROM were noted when matched to the contra-lateral side (P < 0.001) at the 3 month follow-up. The study also showed good healing on radiological evaluation with ultrasonogram 8 weeks after platelet rich plasma injection. Conclusion: Ultrasound guided platelet rich plasma injection for partial rotator cuff tears is an effective procedure that leads to significant decrease in pain, improvement in shoulder functions, much cost-effective and less problematic compared to a surgical treatment.

Ultrasound-guided platelet-rich plasma infiltration: A stupendous treatment for chronic tendinopathy

2016 ◽  
Vol 16 (3) ◽  
pp. 185
Author(s):  
Sohael Khan ◽  
Abhijeet Sahu ◽  
PradeepK Singh ◽  
Shraddha Singhania ◽  
Mahendra Gudhe ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Ultrasound Guided

Leukocyte-rich platelet-rich plasma application in post-traumatic osteoarthritis with popliteal cyst: a case report

2020 ◽  
Vol 15 (6) ◽  
pp. 1695-1702
Author(s):  
Bo Song ◽  
Peter Chia Yeh ◽  
Prathap Jayaram
Keyword(s):  
Platelet Rich Plasma ◽  
Corticosteroid Injection ◽  
Cruciate Ligament ◽  
Symptom Relief ◽  
Basketball Player ◽  
Popliteal Cyst ◽  
Baker’S Cyst ◽  
Baker's Cyst ◽  
Patient Reported ◽  
Post Traumatic

Aim: To describe the successful treatment of a Baker’s cyst in the setting of post-traumatic osteoarthritis using ultrasound-guided injection of platelet-rich plasma. Setting: Outpatient sports clinic. Patient: 29-year old male basketball player. Case description: The patient presented with 2-months history of right knee pain, 17 months after undergoing right knee anterior cruciate ligament reconstruction surgery. Exam revealed medial joint line and medial collateral ligament tenderness with posterior knee swelling. After aspiration, a corticosteroid injection was administered with temporary symptom relief. Diagnostic ultrasound examination confirmed the Baker’s cyst. The patient then underwent two serial leukocyte-rich platelet-rich plasma injections into his right knee. Results: The patient reported complete resolution of pain and cyst size. Conclusion: Leukocyte-rich platelet-rich plasma may be considered as a treatment option for patients with Baker’s cysts in the setting of post-traumatic osteoarthritis.

scholarly journals Use of Ultrasound-Guided Platelet-Rich Plasma Injection of the Sacroiliac Joint as a Treatment for Chronic Low Back Pain

2019 ◽  
Vol 185 (7-8) ◽  
pp. e1312-e1317
Author(s):  
Devin Y Broadhead ◽  
Hannah E Douglas ◽  
Laurie M Bezjian Wallace ◽  
Patrick J Wallace ◽  
Sarah Tamura ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Sacroiliac Joint ◽  
Functional Disability ◽  
Platelet Rich Plasma ◽  
Common Source ◽  
Low Back ◽  
Ultrasound Guided ◽  
Long Term Treatment

ABSTRACT Back pain and its associated complications are of increasing importance among military members. The sacroiliac joint (SIJ) is a common source of chronic low back pain (LBP) and functional disability. Many patients suffering from chronic LBP utilize opioids to help control their symptoms. Platelet-rich plasma (PRP) has been used extensively to treat pain emanating from many different musculoskeletal origins; however, its use in the SIJ has been studied only on a limited basis. The patient in this case report presented with chronic LBP localized to the SIJ and subsequent functional disability managed with high-dose opioids. After failure of traditional treatments, she was given an ultrasound-guided PRP injection of the SIJ which drastically decreased her pain and disability and eventually allowed for complete opioid cessation. Her symptom relief continued 1 year after the injection. This case demonstrates the potential of ultrasound-guided PRP injections as a long-term treatment for chronic LBP caused by SIJ dysfunction in military service members, which can also aid in the weaning of chronic opioid use.

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