Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General

2019 ◽  
Author(s):  
Keyword(s):  
Pulpal Anesthesia

scholarly journals Anesthetic Efficacy of a Combination of 0.5 M Mannitol Plus 127.2 mg of Lidocaine With 50 μg Epinephrine in Inferior Alveolar Nerve Blocks: A Prospective Randomized, Single-Blind Study

2013 ◽  
Vol 60 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Steven Smith ◽  
Al Reader ◽  
Melissa Drum ◽  
John Nusstein ◽  
Mike Beck
Keyword(s):  
Postoperative Pain ◽  
Inferior Alveolar Nerve ◽  
Blind Study ◽  
Maximum Output ◽  
Nerve Blocks ◽  
Posterior Teeth ◽  
Solution Deposition ◽  
The Times ◽  
Pulpal Anesthesia ◽  
Single Blind

Abstract The purpose of this prospective, randomized, single-blind study was to determine the anesthetic efficacy of 127.2 mg lidocaine with 50 μg epinephrine compared to 127.2 mg lidocaine with 50 μg epinephrine plus 0.5 M mannitol in inferior alveolar nerve (IAN) blocks. Forty subjects randomly received 2 IAN blocks consisting of a 3.18 mL formulation of 127.2 mg lidocaine with 50 μg epinephrine and a 5 mL formulation of 127.2 mg lidocaine with 50 μg epinephrine (3.18 mL) plus 0.5 M mannitol (1.82 mL) in 2 separate appointments spaced at least 1 week apart. Mandibular anterior and posterior teeth were blindly electric pulp tested at 4-minute cycles for 60 minutes postinjection. Pain of solution deposition and postoperative pain were also measured. No response from the subject to the maximum output (80 reading) of the pulp tester was used as the criterion for pulpal anesthesia. Total percent pulpal anesthesia was defined as the total of all the times of pulpal anesthesia (80 readings) over the 60 minutes. One hundred percent of the subjects had profound lip numbness with both inferior alveolar nerve blocks. The results demonstrated that a 5 mL formulation of 127.2 mg lidocaine with 50 μg epinephrine plus 0.5 M mannitol was significantly better than the 3.18 mL formulation of 127.2 mg lidocaine with 50 μg epinephrine for all teeth. Solution deposition pain and postoperative pain were not statistically different between the lidocaine/mannitol formulation and the lidocaine formulation without mannitol. We concluded that adding 0.5 M mannitol to a lidocaine with epinephrine formulation was significantly more effective in achieving a greater percentage of total pulpal anesthesia than a lidocaine formulation without mannitol.

Randomized Study of Phentolamine Mesylate for Reversal of Local Anesthesia

2008 ◽  
Vol 87 (7) ◽  
pp. 635-639 ◽  
Author(s):  
M. Laviola ◽  
S.K. McGavin ◽  
G.A. Freer ◽  
G. Plancich ◽  
S.C. Woodbury ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Local Anesthetic ◽  
Dental Treatment ◽  
Randomized Study ◽  
Study Drug ◽  
Negative Consequences ◽  
Double Blind ◽  
Dental Procedures ◽  
Phase 2 Study ◽  
Pulpal Anesthesia

Local anesthetic solutions frequently contain vasoconstrictors to increase the depth and/or duration of anesthesia. Generally, the duration of soft-tissue anesthesia exceeds that of pulpal anesthesia. Negative consequences of soft-tissue anesthesia include accidental lip and tongue biting as well as difficulty in eating, drinking, speaking, and smiling. A double-blind, randomized, multicenter, Phase 2 study tested the hypothesis that local injection of the vasodilator phentolamine mesylate would shorten the duration of soft-tissue anesthesia following routine dental procedures. Participants (122) received one or two cartridges of local anesthetic/vasoconstrictor prior to dental treatment. Immediately after treatment, 1.8 mL of study drug (containing 0.4 mg phentolamine mesylate or placebo) was injected per cartridge of local anesthetic used. The phentolamine was well-tolerated and reduced the median duration of soft-tissue anesthesia in the lip from 155 to 70 min (p < 0.0001).

Successful pulpal anesthesia for symptomatic irreversible pulpitis

2017 ◽  
Vol 148 (4) ◽  
pp. 267-271 ◽  
Author(s):  
Melissa Drum ◽  
Al Reader ◽  
John Nusstein ◽  
Sara Fowler
Keyword(s):  
Pulpal Anesthesia ◽  
Irreversible Pulpitis

scholarly journals Anesthetic Efficacy in Irreversible Pulpitis: A Randomized Clinical Trial

2016 ◽  
Vol 27 (4) ◽  
pp. 381-386 ◽  
Author(s):  
Carlos E. Allegretti ◽  
Roberta M. Sampaio ◽  
Anna C. R. T. Horliana ◽  
Paschoal L. Armonia ◽  
Rodney G. Rocha ◽  
...  
Keyword(s):  
Success Rate ◽  
Nerve Block ◽  
Inferior Alveolar Nerve ◽  
Inferior Alveolar Nerve Block ◽  
Posterior Teeth ◽  
Mandibular Molars ◽  
School Of Dentistry ◽  
Mandibular Posterior Teeth ◽  
Pulpal Anesthesia ◽  
Irreversible Pulpitis

Abstract Inferior alveolar nerve block has a high failure rate in the treatment of mandibular posterior teeth with irreversible pulpitis. The aim of this study was to compare the anesthetic efficacy of 4% articaine, 2% lidocaine and 2% mepivacaine, all in combination with 1:100,000 epinephrine, in patients with irreversible pulpitis of permanent mandibular molars during a pulpectomy procedure. Sixty-six volunteers from the Emergency Center of the School of Dentistry, University of São Paulo, randomly received 3.6 mL of local anesthetic as a conventional inferior alveolar nerve block (IANB). The subjective signal of lip numbness, pulpal anesthesia and absence of pain during the pulpectomy procedure were evaluated respectively, by questioning the patient, stimulation using an electric pulp tester and a verbal analogue scale. All patients reported the subjective signal of lip numbness. Regarding pulpal anesthesia success as measured with the pulp tester, the success rate was respectively 68.2% for mepivacaine, 63.6% for articaine and 63.6% for lidocaine. Regarding patients who reported no pain or mild pain during the pulpectomy, the success rate was, respectively 72.7% for mepivacaine, 63.6% for articaine and 54.5% for lidocaine. These differences were not statistically significant. Neither of the solutions resulted in 100% anesthetic success in patients with irreversible pulpitis of mandibular molars.

Pulpal anesthesia efficacy of four lidocaine solutions injected with an intraligamentary syringe

1994 ◽  
Vol 78 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Eliezer Kaufman ◽  
Vladimer Solomon ◽  
Leah Rozen ◽  
Rudy Peltz
Keyword(s):  
Pulpal Anesthesia

Effect of preoperative oral analgesics on pulpal anesthesia in patients with irreversible pulpitis—a systematic review and meta-analysis

2016 ◽  
Vol 21 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Armin Shirvani ◽  
Sayna Shamszadeh ◽  
Mohammad Jafar Eghbal ◽  
Laleh Alim Marvasti ◽  
Saeed Asgary
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Pulpal Anesthesia ◽  
Irreversible Pulpitis

scholarly journals Efficacy of Pulpal Anesthesia Using a Needle-less Syringe

2020 ◽  
Vol 67 (4) ◽  
pp. 200-206
Author(s):  
Coleman Christensen ◽  
Stephen C. Arnason ◽  
Ross Oates ◽  
Michael Crabtree ◽  
John W. Kersey ◽  
...  
Keyword(s):  
Inferior Alveolar Nerve ◽  
Contralateral Side ◽  
Injection Pain ◽  
Injection Technique ◽  
Single Tooth ◽  
Tooth Type ◽  
Vas Scores ◽  
The Difference ◽  
Mandibular Teeth ◽  
Pulpal Anesthesia

The purpose of this study was to investigate the manufacturer's claims regarding a novel needleless intraligamentary local anesthesia injection device (Numbee, BioDent) to provide effective single tooth anesthesia. Investigators compared the Numbee with a traditional inferior alveolar nerve block (IANB) during a restorative procedure on mandibular teeth. A randomized, split-mouth design was conducted with 15 adult subjects receiving an IANB on one side and a Numbee injection on the same tooth type on the contralateral side. Subjects recorded injection pain using the Visual Analog Scale (VAS) and their preferred injection technique. Anesthesia was considered profound with 2 consecutive electric pulp tester readings of 80. If subjects became symptomatic during the restorative procedure, rescue anesthesia was administered. The difference in VAS scores for injection pain between the Numbee and the IANB was not significant (p = .078). For the IANB, the incidence of profound anesthesia was 46%, and required rescue anesthesia was 20%. For the Numbee, the incidence of profound anesthesia was 0%, and required rescue anesthesia was 60%. Subject preference was evenly split (50/50%) between the 2 techniques. The IANB outperformed the Numbee device for achieving profound anesthesia and requiring less rescue anesthesia.

scholarly journals Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study

2018 ◽  
Vol 65 (3) ◽  
pp. 156-161
Author(s):  
Papimon Chompu-inwai ◽  
Sophon Simprasert ◽  
Patchanee Chuveera ◽  
Areerat Nirunsittirat ◽  
Thanapat Sastraruji ◽  
...  
Keyword(s):  
Nitrous Oxide ◽  
Rating Scale ◽  
Permanent Teeth ◽  
Chi Square ◽  
Significant Difference ◽  
Nitrous Oxide Oxygen ◽  
Chi Square Test ◽  
Preliminary Study ◽  
Pulpal Anesthesia ◽  
Irreversible Pulpitis

To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result.

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