Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers

2019 ◽  
Author(s):  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Adenoid Cystic

Treatment of Adenoid Cystic Carcinoma of the Salivary Gland, a Three-Field Technique

1990 ◽  
Vol 15 (3) ◽  
pp. 99-105 ◽  
Author(s):  
Sharon M. Hummel ◽  
Thomas A. Buchholz ◽  
George E. Laramore
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Field Technique ◽  
Adenoid Cystic

Estrogen receptor expression in salivary gland mucoepidermoid carcinoma and adenoid cystic carcinoma

2004 ◽  
Vol 10 (3) ◽  
pp. 166-168 ◽  
Author(s):  
Fábio Ramôa Pires ◽  
Danyel Elias da Cruz Perez ◽  
Oslei Paes de Almeida ◽  
Luiz Paulo Kowalski
Keyword(s):  
Estrogen Receptor ◽  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Mucoepidermoid Carcinoma ◽  
Receptor Expression ◽  
Estrogen Receptor Expression ◽  
Adenoid Cystic

Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland

Oral Oncology ◽  
2005 ◽  
Vol 41 (9) ◽  
pp. 934-939 ◽  
Author(s):  
Kolja Freier ◽  
Christa Flechtenmacher ◽  
Axel Walch ◽  
Frauke Devens ◽  
Joachim Mühling ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Histological Subtypes ◽  
Adenoid Cystic

scholarly journals Promoter methylation as a common mechanism for inactivatingE-cadherin in human salivary gland adenoid cystic carcinoma

Cancer ◽  
2007 ◽  
Vol 110 (1) ◽  
pp. 87-95 ◽  
Author(s):  
Chun-Ye Zhang ◽  
Li Mao ◽  
Lei Li ◽  
Zhen Tian ◽  
Xiao-Jian Zhou ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Promoter Methylation ◽  
Common Mechanism ◽  
Human Salivary Gland ◽  
Adenoid Cystic

Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours

2012 ◽  
Vol 27 (4) ◽  
pp. 381-388 ◽  
Author(s):  
Mark R. Darling ◽  
Nelly N. Hashem ◽  
Irene Zhang ◽  
Mohamed Mohamed ◽  
Kevin Fung ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumour ◽  
Immunoperoxidase Staining ◽  
Aberrant Expression ◽  
Adenoid Cystic ◽  
Gland Tumour

Objectives Kallikrein-related peptidase 10 (KLK10) has been implicated in the development of several types of cancer. The purpose of this study was to analyze the expression of KLK10 in 3 types of salivary gland tumour and normal salivary glands. Materials and methods: A standard immunoperoxidase staining technique was used to assess the Immunoexpression profile of KLK10 in normal salivary glands and 3 types of salivary gland tumour: pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma. Results Pleomorphic adenomas showed significantly lower KLK10 levels than control tissues. Neither of the malignant tumours (adenoid cystic carcinoma and mucoepidermoid carcinoma) showed a significant alteration in the immunoreactive scores of KLK10 in comparison with the normal salivary gland tissues. KLK10 immunoreactive scores were comparable in adenoid cystic carcinoma and mucoepidermoid carcinoma. Pleomorphic adenoma had significantly lower levels of KLK10 than mucoepidermoid carcinoma. Conclusions The finding of lower KLK10 levels in pleomorphic adenoma suggests aberrant expression in a tumour that develops primarily from myoepithelial cells. A kallikrein cascade may play a role in the development and/or outcome of some salivary gland tumours.

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