Use of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers

2020 ◽  
Author(s):  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

scholarly journals Effects of the Low-Level Laser Therapy (LLLT) in the process of healing diabetic foot ulcers

2015 ◽  
Vol 30 (12) ◽  
pp. 852-857 ◽  
Author(s):  
Maura Cristina Porto Feitosa ◽  
Ana Flávia Machado de Carvalho ◽  
Valrian Campos Feitosa ◽  
Isabely Madalena Coelho ◽  
Rauirys Alencar de Oliveira ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

A Systematic Review and Meta-Analysis of the Effects of Low-Level Laser Therapy in the Treatment of Diabetic Foot Ulcers

2020 ◽  
pp. 153473462091443
Author(s):  
Cristiana Maria dos Santos ◽  
Rebeca Barbosa da Rocha ◽  
Fuad Ahmad Hazime ◽  
Vinicius Saura Cardoso
Keyword(s):  
Systematic Review ◽  
Laser Therapy ◽  
Diabetic Foot ◽  
Meta Analysis ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Diabetic foot ulcers (DFUs) are considered one of the most aggressive and expensive complications of diabetes. Low-level laser therapy (LLLT) has been highlighted as a potential modality of treatment to accelerate the healing of ulcers. This systematic review and meta-analysis aimed to investigate the efficacy of LLLT in the treatment of DFU and identify the LLLT application parameters recommended for the treatment of DFU over the past 10 years. A systematic search was conducted in PubMed, BVS, PEDro, Scopus, Web of Science, and CINAHL up to March 31, 2019. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines, randomized controlled trials (RCTs) that assessed the effect of LLLT on the treatment of DFU were included. Thirteen RCTs with a total of 361 participants were included in this review. Three RCTs reported a reduction in the percentage size of the ulcers and were included in the meta-analysis. The meta-analysis of the percentage size difference demonstrated a significant reduction in ulcer size in the LLLT group compared with controls (22.96 [95% confidence interval = 18.22-27.69; z = 9.51, P < .0001]). Treatment with 632.8 to 685 nm, 50 mW/cm2, 3 to 6 J/cm2, and irradiation for 30 to 80 seconds, 3 times weekly for a month is of benefit to patients with DFU. LLLT is effective and safe for the treatment of DFU. Additionally, well-designed, high-quality studies are needed to allow its ideal parameterization for clinical practice.

scholarly journals EFFECT OF LOW-LEVEL LASER THERAPY ON DIABETIC FOOT ULCERS

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Adha Arunkumar Kailashdan ◽  
Bharai Raviraj Arjunbhai
Keyword(s):  
Laser Therapy ◽  
Bacterial Growth ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Background: Across the globe, diabetes mellitus (DM) is considered as a major health issue because of its prevalence rate tending to increase day by day in a remarkable manner. A foot ulcer is frequently faced complication that is very frequently faced in patients suffering from diabetes mellitus. Diabetic Mellitus is noticed as a severe health issue affecting around 387 million people. The purpose of this study is to study the effect of low level laser therapy on diabetic foot ulcers to control infection, determine best suitable cost-effective technique and aid in studying the role of Low-level laser therapy in the context of treating diabetic foot ulcers. Aim: To study the role of low-level laser therapy on diabetic ulcers Results: The proportion of males was slightly higher than females in both cases and controls. The mean BMI was 26.50±2.444 among cases and mean BMI was 25.27±2.407 among controls. Among 16 grades 1 ulcer, 6 (37.5%) remained in grade 1, 10 (62.5%) ulcers completely healed at the end of 20 days. In group B, 21 subjects had bacterial growth on day-1, and the remaining 19 had no bacterial growth. Out of the 21 with bacterial growth, 15(71.42%) still had growth at the end of 20 days, and 6 (28.58%) had no growth. Methods: The current study was a randomized open labelled control study, with randomised two treatment groups [Group A: Intervention group (who received laser therapy in addition to standard management)  Group B: Control group (standard treatment group)] and total sample size of 80 performed at the Department of Surgery, Banas Medical College and Research Institute, Palanpur, Gujarat between Jan-17 to Dec-17. Descriptive analysis was carried out by mean and standard deviation for quantitative variables, frequency and proportion for categorical variables. Data was also represented using appropriate diagrams like a bar diagram, pie diagram and box plots. The area of the ulcer was compared between the two groups, using independent sample t-test. The mean differences along with their 95% CI were presented. Association between quantitative explanatory and outcome variables was assessed by calculating the Pearson correlation coefficient and the data was represented with P-value. Conclusion: It can be concluded that Laser therapy is best-suited therapy for curing the diabetic foot ulcer as it is pain-free, effective on budget, wound contraction as well as re- epithelialisation helped in accelerating the curing of the wound with simple curing process following proper medication and instructions provided with laser therapy. Control of infection becomes easy as compared to any other techniques being used such as split skin grafting, and other secondary expensive procedures attempted to cure DFU.

Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers

2016 ◽  
Vol 32 (2) ◽  
pp. 275-282 ◽  
Author(s):  
R. K. Mathur ◽  
Khageswar Sahu ◽  
Siddharth Saraf ◽  
Pooja Patheja ◽  
Fareed Khan ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Conventional Therapy ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

scholarly journals Low Level Laser Therapy for the Treatment of Diabetic Foot Ulcers: A Critical Survey

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Kathrin H. Beckmann ◽  
Gesa Meyer-Hamme ◽  
Sven Schröder
Keyword(s):  
Clinical Trials ◽  
Laser Therapy ◽  
Diabetic Foot ◽  
Animal Studies ◽  
Wound Care ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level Laser ◽  
Level Laser

Diabetic foot ulcers as one of the most common complications of diabetes mellitus are defined as nonhealing or long-lasting chronic skin ulcers in diabetic patients. Multidisciplinary care for the diabetic foot is common, but treatment results are often unsatisfactory. Low level laser therapy (LLLT) on wound areas as well as on acupuncture points, as a noninvasive, pain-free method with minor side effects, has been considered as a possible treatment option for the diabetic foot syndrome. A systematic literature review identified 1764 articles on this topic. Finally, we adopted 22 eligible references; 8 of them were cell studies, 6 were animal studies, and 8 were clinical trials. Cell studies and animal studies gave evidence of cellular migration, viability, and proliferation of fibroblast cells, quicker reepithelization and reformed connective tissue, enhancement of microcirculation, and anti-inflammatory effects by inhibition of prostaglandine, interleukin, and cytokine as well as direct antibacterial effects by induction of reactive oxygen species (ROS). The transferral of these data into clinical medicine is under debate. The majority of clinical studies show a potential benefit of LLLT in wound healing of diabetic ulcers. But there are a lot of aspects in these studies limiting final evidence about the actual output of this kind of treatment method. In summary, all studies give enough evidence to continue research on laser therapy for diabetic ulcers, but clinical trials using human models do not provide sufficient evidence to establish the usefulness of LLLT as an effective tool in wound care regimes at present. Further well designed research trials are required to determine the true value of LLLT in routine wound care.

scholarly journals Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers

2016 ◽  
Vol 50 (4) ◽  
pp. 628-634 ◽  
Author(s):  
Ana Flávia Machado de Carvalho ◽  
Maura Cristina Porto Feitosa ◽  
Nayana Pinheiro Machado de Freitas Coelho ◽  
Veruska Cronemberger Nogueira Rebêlo ◽  
Juçara Gonçalves de Castro ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Essential Fatty Acids ◽  
Ankle Brachial Index ◽  
Low Level Laser Therapy ◽  
Diabetic Foot Ulcers ◽  
Calendula Officinalis ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Abstract OBJECTIVE To evaluate the effects of low-level laser therapy isolated and associated with Calendula officinalis oil in treating diabetic foot ulcers. METHOD An experimental, randomized, controlled, prospective, interventional clinical case study using a quantitative approach. The sample consisted of 32 diabetic patients of both genders. Participants were randomly divided into four groups. Doppler Ultrasound evaluation of the Ankle-Brachial Index, brief pain inventory and analog pain scale were performed at baseline and after 30 days. RESULTS Reduced pain was observed in the Low-level laser therapy and Low-level laser therapy associated with Essential Fatty Acids groups (p<0.01). Regarding the Ankle-Brachial Index and Doppler Ultrasound, all groups remained stable. By analyzing lesion area reduction, Low-level laser therapy associated with Essential fatty acids group showed a significance of p=0.0032, and the Low-level laser therapy group showed p=0.0428. CONCLUSION Low-level laser therapy, performed alone or associated with the Calendula officinalis oil was effective in relieving pain and accelerating the tissue repair process of diabetic foot.

scholarly journals Effects of low-level laser therapy on the healing of foot ulcers in people with diabetes mellitus

2020 ◽  
Author(s):  
Maria Girlane Sousa Albuquerque Brandão ◽  
Maria Aline Moreira Ximenes ◽  
Aline de Oliveira Ramalho ◽  
Vivian Saraiva Veras ◽  
Lívia Moreira Barros ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Healing Process ◽  
Low Level Laser Therapy ◽  
Limb Amputation ◽  
Wound Healing Process ◽  
Eligibility Criteria ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Objective: Identify the effects of low-level laser therapy on the healing of diabetic foot. Method: Systematic review of the PubMed, LILACS, SciELO, CINAHL, Cochrane, Web of Science and Scopus databases, in which 92 articles were identified and six were included in the final sample after the eligibility criteria. Results: The articles pointed out as effects of laser therapy the effectiveness in the progression of the tissue repair process of the diabetic foot, pain relief, anti-inflammatory action, increased tissue perfusion of the lesion and improvement of the vascular response and the nervous system. Conclusion: Laser is an adjuvant therapy that can accelerate the wound healing process, relieve pain, improve neovascularization, and thus minimize the risk of complications, such as lower limb amputation and improvement of quality of life for people with diabetes and impaired skin integrity.

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