scholarly journals Osteoporosis Prevalence and Correlates in Uncomplicated Type 2 Diabetes Mellitus

2021 ◽  
Vol 4 (1) ◽  
pp. 01-06
Author(s):  
Amit Nachankar ◽  
Jitendra Sahu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Coronary Artery Disease ◽  
Type 2 Diabetes Mellitus ◽  
Arterial Disease ◽  
Increased Risk ◽  
Artery Disease ◽  
Peripheral Arterial ◽  
Osteoporosis Prevalence

Type 2 Diabetes Mellitus (T2DM) is a common metabolic disorder at a pandemic proportion at present. Often T2DM is associated with microvascular (diabetic nephropathy, neuropathy, and retinopathy) and macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke). Additionally diabetic osteopathy is a significant comorbidity of T2DM and is characterized by micro architectural changes that decrease bone quality leading to an increased risk of fragility fracture.

scholarly journals High Systolic and Diastolic Blood Pressure Variability Is Correlated with the Occurrence of Peripheral Arterial Disease in the First Decade following a Diagnosis of Type 2 Diabetes Mellitus: A New Biomarker from Old Measurement

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Chi-Hsiao Yeh ◽  
Hsiu-Chin Yu ◽  
Tzu-Yen Huang ◽  
Pin-Fu Huang ◽  
Yao-Chang Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Arterial Disease ◽  
Risk Group ◽  
Arterial Disease ◽  
Increased Risk ◽  
Peripheral Arterial

Background. To assess whether the visit-to-visit variability in blood pressure (BP) is a risk factor of peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus (T2DM) 10 years after diagnosis. Methods. The electronic medical records of 825 patients, who were diagnosed with type 2 diabetes mellitus (T2DM) during 2000–2002 and regularly followed for 10 years, were retrospectively reviewed. A total of 53,284 clinic visit records, including analysis of BP, BMI, serum glycohemoglobin, and lipid profile, were analyzed. Results. Patients were categorized into two groups according to their visit-to-visit variability in systolic and diastolic BP (SBP and DBP, resp.). The high-risk group included patients with high SBP and DBP visit-to-visit variability; this group had a 1.679-fold (95% CI: 1.141–2.472, P=0.009) increased risk of PAD compared with patients in the low-risk group. Cox regression analysis also demonstrated that the age at which the patients were diagnosed with T2DM, smoking status, and mean creatinine level was significantly associated with increased risk of PAD with a hazard ration of 1.064 (95% CI: 1.043–1.084, P<0.001), 1.803 (95% CI: 1.160–2.804, P=0.009), and 1.208 (95% CI: 1.042–1.401, P=0.012), respectively. Conclusions. High SBP and DBP visit-to-visit variability is correlated with PAD in the first decade following a diagnosis of T2DM.

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