The Effect of Daily Massive Doses of Viosterol upon Calcium and Phosphorus Metabolism and Blood Calcium and Inorganic Phosphorus in Calves

ABSTRACT A study of calcium and phosphorus metabolism has been carried out on 13 acromegalic patients, in various stages of the disease. This study was repeated in nine patients following implantation of the pituitary gland with 90Y and in another two patients after deep X-ray therapy and suction removal of a pituitary adenoma respectively. Increased urinary calcium and phosphorus excretion was found in all the patients in whom the disease was in an active phase of evolution. The calcium tolerance test revealed a marked decrease of calcium retention in certain subjects, while in others, calcium retention was found to be increased. Such changes were not found in patients in whom the disease was in a quiescent phase. The blood calcium, phosphorus and alkaline phosphatase were found to be either normal or slightly increased. The implantation of the pituitary gland with 90Y and deep X-ray therapy induced a marked decrease of hypercalciuria, both spontaneous and induced, and of hyperphosphaturia, together with a definite improvement, of the clinical picture and glucose metabolism. It is concluded that the changes in calcium and phosphorus metabolism described above depend either directly or indirectly on a pituitary factor. They may therefore prove a reliable index for assessing pituitary growth hormone activity.

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PHOSPHATE EXCRETION AND PARATHYROID FUNCTION IN THYROTOXICOSIS

Journal of Endocrinology ◽

10.1677/joe.0.0280281 ◽

1964 ◽

Vol 28 (3) ◽

pp. 281-288 ◽

Cited By ~ 36

Author(s):

R. McG. HARDEN ◽

M. T. HARRISON ◽

W. D. ALEXANDER ◽

B. E. C. NORDIN

Keyword(s):

Inorganic Phosphorus ◽

Plasma Calcium ◽

Phosphorus Metabolism ◽

Phosphate Excretion ◽

Parathyroid Function ◽

Calcium And Phosphorus ◽

High Phosphate

SUMMARY Certain aspects of calcium and phosphorus metabolism have been studied in thirty-six patients with thyrotoxicosis. The plasma calcium and inorganic phosphorus concentrations were not significantly different from normal. The basal phosphate excretion index was low (− 0·08 ± 0·01) and there was an impaired response to high phosphate feeding. These findings suggest that parathyroid function is reduced in thyrotoxicosis.

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Calcium and phosphorus balances with laying birds

The Journal of Agricultural Science ◽

10.1017/s0021859600047535 ◽

1942 ◽

Vol 32 (1) ◽

pp. 43-61 ◽

Cited By ~ 30

Author(s):

Cyril Tyler ◽

James Stuart Willcox

Keyword(s):

Calcium Carbonate ◽

Laying Hens ◽

Calcium Sulphate ◽

Phosphorus Metabolism ◽

Shell Formation ◽

Review Of The Literature ◽

Blood Calcium ◽

Calcium And Phosphorus ◽

Egg Shell ◽

General Aspects

1. A series of balance experiments to compare calcium carbonate, calcium sulphate and calcium gluconate as sources of calcium for laying hens is described.2. Not one of the three supplements showed all-round superiority, but calcium sulphate was the worst.3. The main results indicate that:(a) Calcium sulphate and gluconate cause scouring but carbonate does not.(b) The best retention of calcium occurs with gluconate and the worst with sulphate.(c) Calcium carbonate gives the best shells and calcium sulphate the worst.4. The experiments also throw fresh light on some more general aspects of calcium and phosphorus metabolism.5. On the basis of these general results and a review of the literature of blood calcium and phosphorus in laying hens a theory dealing with certain aspects of egg-shell formation is presented.

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Observations on the mineral metabolism of pullets: VIII. The influence of gonadal hormones on retention of calcium and phosphorus

The Journal of Agricultural Science ◽

10.1017/s0021859600005153 ◽

1948 ◽

Vol 38 (1) ◽

pp. 64-80 ◽

Cited By ~ 44

Author(s):

R. H. Common ◽

W. A. Rutledge ◽

R. W. Hale

Keyword(s):

Mineral Metabolism ◽

Gonadal Hormones ◽

Phosphorus Metabolism ◽

Phosphorus Retention ◽

Blood Calcium ◽

Calcium And Phosphorus

SUMMARY1. Sexually immature White Wyandotte pullets have been treated with gonadal hormones with the object of simulating those changes in calcium and phosphorus metabolism which normally take place during the fortnight or so before laying begins.2. It is shown that certain treatments of the sexually immature pullet with oestradiol dipropionate evoked hypertrophy of the oviduct and changes in blood calcium and phosphorus similar to those encountered in the normal laying pullet, but did not produce any significant increase in the rate of calcium or phosphorus retention.

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