scholarly journals Resection of a dominant-hemisphere intraventricular meningioma facilitated by functional magnetic resonance imaging

2001 ◽  
Vol 10 (6) ◽  
pp. 1-5 ◽  
Author(s):  
William T. Curry ◽  
G. Rees Cosgrove ◽  
Bradley R. Buchbinder ◽  
Robert G. Ojemann

Intraventricular meningiomas of the lateral ventricle occur relatively rarely, but they are often large at the time of detection and present more commonly on the left side. Although the ability to resect these tumors safely has greatly improved over time, standard surgical approaches often traverse cortex close to areas of specific cortical function. Precise cortical mapping of language and sensorimotor cortices can be accomplished noninvasively by using functional magnetic resonance (fMR) imaging. The authors used fMR imaging in planning the cortical incision for resection of a large intraventricular trigone meningioma in the dominant hemisphere of a patient who, postoperatively, suffered no aphasia or hemiparesis. The authors discuss the advantages of mapping cortical function preoperatively with fMR imaging when approaching intraventricular lesions.

2002 ◽  
Vol 97 (2) ◽  
pp. 319-327 ◽  
Author(s):  
Charles N. Bernstein ◽  
Uta N. Frankenstein ◽  
Patricia Rawsthorne ◽  
Marshall Pitz ◽  
Randy Summers ◽  
...  

Author(s):  
Xiaoping Hu ◽  
Tuong Le ◽  
Seong-Gi Kim ◽  
Kamil Ugurbil

In the past few years, one of the most significant developments in magnetic resonance imaging (MRI) is the use of MR imaging to non-invasively map human cortical function without the use of exogenous contrast agents . Since its introduction in 1992, functional magnetic resonance imaging (fMRI) has emerged as a powerful tool for studying neuronal function and generated an enormous amount of interest among neuroscientists, NMR scientists, and clinicians. The purpose of this paper is to outline the principle of fMRI and the associated technical issues and illustrate the utility of fMRI with representative applications.The basis of fMRI is the blood oxygenation level dependent (BOLD) contrast which is derived from the fact that deoxyhemoglobin is paramagnetic and changes in the local concentration of deoxyhemoglobin within the brain lead to alterations in the magnetic resonance signal. Neuronal activation within the cerebral cortex causes an increase in blood flow without a commensurate increase in oxygen extraction.


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