scholarly journals Discography interpretation and techniques in the lumbar spine

2002 ◽  
Vol 13 (2) ◽  
pp. 1-8 ◽  
Author(s):  
Frank J. Tomecek ◽  
C. Scott Anthony ◽  
Chris Boxell ◽  
Jennifer Warren
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Nucleus Pulposus ◽  
Diagnostic Test ◽  
Diagnostic Tool ◽  
Radiographic Evaluation ◽  
Low Back

The authors provide an indepth analysis of discography, a provocative diagnostic tool to determine the origin of low-back pain. Injecting the intervertebral disc with radiopaque dye provides physicians with several useful pieces of information. First, the modality provides radiographic evaluation of the integrity of the nucleus pulposus and anular rings to determine tears or other lesions that could be creating low-back pain. Second, and very important, is its measure of disc nociception. A normal disc should not cause pain when injected; however, a disc that is physiologically compromised can mimic the pain previously experienced by a patient. The authors review the indications, technique, and interpretation of discography to allow a better understanding of when to use this diagnostic test and what to do with the results.

scholarly journals Intervertebral Disc Degeneration and Low Back Pain: Molecular Mechanisms and Stem Cell Therapy

2018 ◽  
Vol 10 (1) ◽  
pp. 1 ◽  
Author(s):  
Anna Meiliana ◽  
Nurrani Mustika Dewi ◽  
Andi Wijaya
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Nucleus Pulposus ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Low Back

BACKGROUND: Low back pain (LBP) mostly caused by disc degeneration, reflects to a tremendous of health care system and economy. More knowledge about these underlying pathologies will improve the opportunities that may represent critical therapeutic targets.CONTENT: Basic research is advancing the understanding of the pathogenesis and management of LBP at the molecular and genetic levels. Cytokines such as matrix metalloproteinases, phospholipase A2, nitric oxide, and tumor necrosis factor-α are thought to contribute to the development of LBP. Mesenchymal stem cells (MSCs) transplant to cartilage-like cells and secrete extracellular matrix and encourage nucleus pulposus (NP) cell activity inhibiting NP cell apoptosis, together with some chemical mediators such as cytokines and growth factors become a safe and effective new strategy for intervertebral disc degeneration (IDD) treatment and regeneration.SUMMARY: IDD occurs where there is a loss of homeostatic balance with a predominantly catabolic metabolic profile. A basic understanding of the molecular changes occurring in the degenerating disc is important for practicing clinicians to help them to inform patients to alter lifestyle choices, identify beneficial or harmful supplements, or offer new biologic, genetic, or stem cell therapies.KEYWORDS: low back pain (LBP), intervertebral disc (IVD), degeneration, nucleus pulposus (NP), annulus fibrosus (AF), extracellular matrix (ECM), genetic, stem cells

scholarly journals Clinical research on the efficacy and safety of Bosinji for low back pain with radiculopathy caused by herniated intervertebral disc of the lumbar spine

Medicine ◽  
2018 ◽  
Vol 97 (50) ◽  
pp. e13684 ◽  
Author(s):  
Bonhyuk Goo ◽  
Sung-Jin Kim ◽  
Eun-Jung Kim ◽  
Dongwoo Nam ◽  
Hyun-Jong Lee ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Clinical Research ◽  
Low Back ◽  
Efficacy And Safety ◽  
Herniated Intervertebral Disc

scholarly journals Effect of Physiotherapy on Back Pain and Function after the L4/L5 Disc Hernia Surgery

2019 ◽  
Vol 2 (15) ◽  
Author(s):  
Eglė Štafėlaitė ◽  
Saulė Sipavičienė
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Physical Therapy ◽  
Intervertebral Disc ◽  
Functional Disability ◽  
Low Back ◽  
Hernia Surgery ◽  
Disc Hernia ◽  
Spine Mobility

Research background. A popular physiotherapy mean is spine stability exercises, but still not so many studies have been carried out about the benefts of this technique in patients after L4/L5 spinal hernia surgery during the acute period. The aim was to assess the effectiveness of spine stabilizing exercises in patients after spinal L4/L5 intervertebral disc hernia surgery for back pain and functional status. Methods. The motion of fear evaluation, using physical therapy questionnaire (TAMPA), functional disability evaluation, using Oswestry functional disability index questionnaire, pain assessment using a symptom assessment scale (SAS), lumbar spine motility measurement, using Sober test, static endurance measurement of the waist muscles. Results. After physical therapy program back pain and functional disability decreased, back and abdominal muscle endurance and lumbar spine mobility increased. Conclusions. The patients after spinal L4/L5 intervertebral disc hernia surgery low back pain decreased and functional disability increased after applied to the spine stabilization exercises.Keywords: intervertebral disc hernia, low back pain, spine stabilizing exercises. 

scholarly journals A study of the effects of chiropractic therapy on the diameter of the spinal canal of patients with low back pain and radiculopathy

1996 ◽  
Author(s):  
◽  
Bradley Stuart Beira
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Spinal Canal ◽  
Low Back ◽  
Lumbar Intervertebral Disc ◽  
Chiropractic Therapy

Focus during this investigation was directed towards determining alterations in the size of the lumbar intervertebral disc in patients symptomatic with low back pain and sciatic distribution pain, in response to chiropractic management of this condition. The efficacy of chiropractic management for low back pain with associated radiculopathy has been examined. Flexion distraction technique and side posture rotatory adjustment technique of the lumbar spine have been used during this trial.

Enucleated Nucleus Pulposus-Induced Intervertebral Disc Degeneration as an Animal Model for Chronic Low Back Pain

2011 ◽  
Vol 11 (10) ◽  
pp. S87-S88
Author(s):  
Jae-Sung Kim ◽  
Jeffrey Kroin ◽  
Howard An ◽  
Xin Li ◽  
Dongyao Yan ◽  
...  
Keyword(s):  
Animal Model ◽  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Nucleus Pulposus ◽  
Disc Degeneration ◽  
Chronic Low Back Pain ◽  
Intervertebral Disc Degeneration ◽  
Low Back
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