Potentiating effects of extraluminal oxyhemoglobin to intraluminal 5-hydroxytryptamine in isolated canine internal carotid arteries

1988 ◽  
Vol 69 (2) ◽  
pp. 263-268 ◽  
Author(s):  
Yuichiro Tanaka ◽  
Shigetoshi Chiba

✓ The interaction between oxyhemoglobin (oxyHb) and 5-hydroxytryptamine (5-HT) was investigated in an experimental model of isolated canine internal and common carotid arteries with insertion of stainless steel cannulae. Extraluminal application of 10−5 M oxyHb induced marked and long-lasting vasoconstriction in the internal carotid but not in the common carotid arteries. The 5-HT-induced vasoconstriction was potentiated significantly in both the internal and common carotid arteries. These potentiations were not influenced by the presence or absence of endothelium, a finding which was confirmed by vascular responses to intraluminal acetylcholine. It is concluded that the interaction between extraluminal oxyHb and intraluminal 5-HT may be one of the possible etiological factors behind the chronic phase of vascular spasm following subarachnoid hemorrhage.

1980 ◽  
Vol 53 (3) ◽  
pp. 300-304 ◽  
Author(s):  
Toshisuke Sakaki ◽  
Kazuhiko Kinugawa ◽  
Tatsuo Tanigake ◽  
Seiji Miyamoto ◽  
Kikuo Kyoi ◽  
...  

✓ Embolism from an aneurysm is one of the mechanisms involved in the pathogenesis of ischemic symptoms associated with intracranial aneurysms. Four cases are reported in which aneurysms of the internal carotid arteries and middle cerebral arteries were the source of emboli resulting in cerebral infarction. In the treatment of these aneurysms, it is best to clip the neck of the aneurysm with great care to avoid embolism due to extrusion of clot into the distal artery.


1978 ◽  
Vol 49 (1) ◽  
pp. 0107-0110 ◽  
Author(s):  
Gulshan K. Ahuja ◽  
Neeraj Jain ◽  
Malini Vijayaraghavan ◽  
Subimal Roy

✓ A young man who had a long history of sinusitis developed subarachnoid hemorrhage and died. Autopsy showed a mycotic aneurysm of fungal origin at the junction of the right posterior cerebral and internal carotid arteries. Four of five reported cases of fungal aneurysm were due to Aspergillus infection.


1979 ◽  
Vol 50 (6) ◽  
pp. 747-757 ◽  
Author(s):  
Roger W. Countee ◽  
Thurairasah Vijayanathan

✓ The authors describe their experiences with five patients with delayed transient ischemic symptoms homolateral to internal carotid artery (ICA) occlusions. In each instance, initial arteriograms were interpreted as showing irreversible occlusions of these arteries in the neck and microvascular bypass procedures were contemplated. However, after repeat arteriographic evaluations with a modified injection technique, certain angiographic features were identified that suggested the mechanism of the symptoms in these patients and that their ICA's could be reconstituted in the neck. This was successfully accomplished in each patient with complete relief of ischemic symptoms. The angiographic technique employed and the arterial flow patterns identified in these patients are discussed. The details of the operative technique are described. It is concluded that routine arteriographic techniques may be inadequate to identify the reversible carotid occlusion. This may account for some of the confusion which surrounds the surgery of these vessels as well as the failure of extracranial-intracranial bypass to relieve recurrent ischemic symptoms in these individuals.


1997 ◽  
Vol 87 (3) ◽  
pp. 436-439 ◽  
Author(s):  
Keiichiro Maeda ◽  
Hiroki Kurita ◽  
Tsuneo Nakamura ◽  
Masaaki Usui ◽  
Kazuo Tsutsumi ◽  
...  

✓ The authors present two rare cases of severe cerebral vasospasm following the rupture of arteriovenous malformations (AVMs). Computerized tomography revealed intracerebral hemorrhage in the thalamus in one case and in the putamen in the other, both accompanied by cast formation of intraventricular clots without radiological evidence of subarachnoid hemorrhage. Initial angiograms showed arterial narrowing of the bilateral internal carotid arteries in the supraclinoid portion but failed to demonstrate an arteriovenous shunt. Subsequent angiograms clearly demonstrated the existence of an AVM. Radiological features and possible mechanisms are discussed.


1980 ◽  
Vol 53 (4) ◽  
pp. 566-569 ◽  
Author(s):  
Koichi Matsuo ◽  
Shigeaki Kobayashi ◽  
Kenichiro Sugita

✓ A case of bitemporal hemianopsia in a 68-year-old woman is reported. Surgical exploration revealed bilateral compression of the optic nerves by the arteriosclerotic internal carotid arteries. Microsurgical decompression with unroofing of the optic canals resulted in prompt recovery of the visual fields.


1978 ◽  
Vol 48 (6) ◽  
pp. 1026-1029 ◽  
Author(s):  
Antti Servo ◽  
Matti Puranen

✓ A case is reported with occlusion and stenosis of the internal carotid arteries in association with basal telangiectasia. Fifteen years after postoperative irradiation for an optic glioma, radiological signs typical of the moyamoya syndrome were observed. Radiation therapy is discussed as the cause of the vascular damage in this case.


Author(s):  
O. Belyaeva ◽  
V. Mandal ◽  
N. Ananyeva ◽  
O. Berkovich ◽  
E. I. Baranova ◽  
...  

Severity of atherosclerosis of common carotid arteries in patients with abdominal obesity (aged from 30 to 55 years old) was evaluated by ultrasound duplex scan. Atherosclerotic plaques of common and/or internal carotid arteries were revealed in 35% of patients. Correlations were observed between intima-media thickness of the common carotid artery, blood pressure levels, waist circumference and metabolic parameters.


1971 ◽  
Vol 34 (6) ◽  
pp. 823-826 ◽  
Author(s):  
Naim K. Atallah ◽  
Sami I. Nassar

✓ The sources of blood supply of calvarial hemangiomas are not well established angiographically but have been reported to derive from the middle meningeal artery. A case is presented in which both the external and the internal carotid arteries supplied the hemangioma. The protean arteriographic picture is explained in terms of the various tissues the tumor involves (galea, calvarium, or meninges).


1971 ◽  
Vol 34 (5) ◽  
pp. 647-651 ◽  
Author(s):  
Francesco Galligioni ◽  
Giorgio Iraci ◽  
Gino Marin

✓ Fibromuscular hyperplasia is an alteration of the arterial wall, affecting mostly middle-aged women. When localized to the internal carotid arteries, it can give symptoms of intermittent or permanent cerebral ischemia, but is usually asymptomatic. Three cases, all of them accidental angiographic findings, are used as a basis for discussion of the angiographic features, differential diagnosis, and surgical treatment.


1977 ◽  
Vol 46 (1) ◽  
pp. 72-77 ◽  
Author(s):  
Carys M. Bannister ◽  
Lesley A. Mundy ◽  
Janice E. Mundy

✓ Autogenous cervical veins were grafted into the common carotid arteries of rabbits during their active growing period. A patency rate of 58.8% was achieved but the thin-walled vein grafts underwent massive dilatation. This dilatation is likely to severely limit the usefulness of these veins as a source of bridging grafts in clinical practice, particularly for use within the intracranial cavity.


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