scholarly journals Long-Term Outcome of Patients with Spinal Dural Arteriovenous Fistula: The Dilemma of Delayed Diagnosis

2020 ◽  
Vol 41 (2) ◽  
pp. 357-363 ◽  
Author(s):  
F. Jablawi ◽  
G.A. Schubert ◽  
M. Dafotakis ◽  
J. Pons-Kühnemann ◽  
F.-J. Hans ◽  
...  
2015 ◽  
Vol 83 (6) ◽  
pp. 1002-1005 ◽  
Author(s):  
Patrick Schuss ◽  
Frederick H. Daher ◽  
Susanne Greschus ◽  
Hartmut Vatter ◽  
Erdem Güresir

2017 ◽  
Vol 159 (11) ◽  
pp. 2113-2122 ◽  
Author(s):  
Yosuke Nishimuta ◽  
Ryuji Awa ◽  
Sei Sugata ◽  
Tetsuya Nagayama ◽  
Tsuneo Makiuchi ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Haiyan Xu ◽  
Xiaozhou He ◽  
Renfang Xu

Antibody-mediated rejection (ABMR) of renal allograft lacks typical phenotypes and clinical manifestations, always resulting in delayed diagnosis and treatment. It has been considered to be an elemental factor influencing the improvement of the long-term outcome of renal allograft. The B cell activating factor (BAFF) signal plays a fundamental function in the process of antibody-mediated immune response. Data from recipients and the nonhuman primate ABMR model suggest that the BAFF signal participates in the ABMR of renal allograft, while there are objections. The challenges in the diagnosis of ABMR, different study population, and details of research may explain the discrepancy. Large quantities of dynamic, credible data of BAFF ligands and their association with renal allograft pathological characteristics would constitute a direct proof of the role of BAFF in the progression of renal allograft ABMR.


2017 ◽  
Vol 18 (6) ◽  
pp. 515-521 ◽  
Author(s):  
Michael Darcy ◽  
Neeta Vachharajani ◽  
Tracy Zhang ◽  
Naganathan Mani ◽  
Seung Kwon Kim ◽  
...  

Introduction Functional arteriovenous fistula (AVF) is the best vascular access for end-stage renal disease patients. AVF maturation is variable and many require additional interventions to achieve functionality. Long-term benefits of such interventions are unclear. Using a protocol for AVF planning, creation, maturation evaluation and performing interventions based on objective findings along with maintaining a database on follow-up is necessary to evaluate this question. The aim of this study is to evaluate the long-term outcome of newly constructed AVFs using a protocol-based approach in a tertiary care academic center. Methods This is an observational study. Long-term outcomes of consecutive AVFs placed over a 5-year period using a protocol for creation, maturation evaluation and interventions based on objective findings were analyzed using a prospectively maintained clinical database. Results Functioning AVFs were achieved in 86.5% (n = 296) of 342 patients. Primary and secondary patency of 372 AVF procedures at 12, 24 and 60 months were 42.8%, 31.6% and 20.8%; and 81.8%, 77.6% and 71.7%, respectively. Functional patency at 12, 24 and 60 months were 95.1%, 88.7%, and 85.2%, respectively. Long-term function was similar for AVFs maturing with ≤4 interventions and without interventions. AVFs maturing with 2-4 interventions needed significantly more interventions to maintain long-term functional patency (p = 0.003). Conclusions Piggyback straight-line on-lay technique (pSLOT) improves early outcome providing opportunity to identify other problems contributing to non-maturation. A large number of AVFs needing planned interventions to mature provide good long-term function. Establishing process of care guidelines for creation and follow-up has a potential to improve AVF outcome.


Anaesthesia ◽  
2020 ◽  
Vol 75 (12) ◽  
pp. 1684-1684
Author(s):  
A. J. R. Macfarlane ◽  
R. Kearns ◽  
M. Clancy ◽  
E. Aitken

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