Focal spot imaging by means of acoustic radiation force: novel method to predict thermocoagulation spot of high-intensity focused ultrasound

Choonpa Igaku ◽  
2013 ◽  
Vol 40 (5) ◽  
pp. 495-506 ◽  
Author(s):  
Osamu ARAI ◽  
Takashi AZUMA ◽  
Ken-ichi KAWABATA ◽  
Yoshihiro MURAGAKI ◽  
Hiroshi ISEKI
2019 ◽  
Vol 5 (1) ◽  
pp. 589-592
Author(s):  
Benedikt George ◽  
Michael Fink ◽  
Helmut Ermert ◽  
Stefan J. Rupitsch ◽  
Stefan Lyer ◽  
...  

AbstractMagnetic Drug Targeting (MDT) is a cancer treatment technique that enables a local chemotherapy. In MDT, chemotherapeutic drugs are bound to magnetic nanoparticles and are accumulated in the tumor area by means of an external magnetic field. Unfortunately, a single magnet can only generate a pulling magnetic force. However, in some applications a pushing force on the nanoparticles could be advantageous. One way to realize pushing forces is to exploit the acoustic radiation force based on the nonlinearity of sound propagation in fluid media generated by a high intensity focused ultrasonic transducer. In this context, we built a test setup was built to investigate the utility of High Intensity Focused Ultrasound (HIFU) to generate a pushing force on the magnetic nanoparticles. The results show that the acoustic radiation force can be employed for particle guidance to achieve concentration differences similar to those obtained by using an electromagnet.


2005 ◽  
Vol 117 (6) ◽  
pp. 3740-3749 ◽  
Author(s):  
Wen-Shiang Chen ◽  
Ping-Mo Ma ◽  
Hao-Li Liu ◽  
Chih-Kuang Yeh ◽  
Min-Shin Chen ◽  
...  

2017 ◽  
Author(s):  
Maria Karzova ◽  
Anastasia Nikolaeva ◽  
Sergey Tsysar ◽  
Vera Khokhlova ◽  
Oleg Sapozhnikov

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