Phospholipase C Effect on Water, Sodium, Potassium Content and Amino Acid Transport of Kidney Cortex Slices

1971 ◽  
Vol 138 (1) ◽  
pp. 294-297
Author(s):  
D. M. Brown ◽  
A. F. Michael
1962 ◽  
Vol 40 (11) ◽  
pp. 1591-1602 ◽  
Author(s):  
P. N. Abadom ◽  
P. G. Scholefield

Evidence is presented which indicates that several amino acid transport systems are present in rat brain cortex slices, each with its own specificity with regard to substrate and with regard to amino acids which produce inhibitory effects. The nature of these inhibitory effects may be either direct (competition for a limiting number of sites) or indirect (as they are when glutamate or aspartate cause a decrease in the ATP content).Comparison of the specificities of the glycine transport systems present in rat brain cortex slices and in Ehrlich ascites carcinoma cells indicates that these two systems have little in common and the relation of this finding to the structural requirements necessary for chemotherapeutic activity is discussed.


Science ◽  
1974 ◽  
Vol 184 (4132) ◽  
pp. 68-69 ◽  
Author(s):  
R. Reynolds ◽  
C. Rea ◽  
S. Segal

1967 ◽  
Vol 135 (1) ◽  
pp. 127-135 ◽  
Author(s):  
Stanton Segal ◽  
Leonard Schwartzman ◽  
Alberta Blair ◽  
Dolores Bertoli

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